CLIP170 inhibits the metastasis and EMT of papillary thyroid cancer through the TGF-β pathway

Rossi ED, Pantanowitz L, Hornick JL. A worldwide journey of thyroid cancer incidence centred on tumour histology. Lancet Diabetes Endocrinol. 2021;9(4):193–4.

Article  PubMed  Google Scholar 

Miranda-Filho A, Lortet-Tieulent J, Bray F, Cao B, Franceschi S, Vaccarella S, Dal Maso L. Thyroid cancer incidence trends by histology in 25 countries: a population-based study. Lancet Diabetes Endocrinol. 2021;9(4):225–34.

Article  PubMed  Google Scholar 

Mazzaferri EL, Jhiang SM. Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer. Am J Med. 1994;97(5):418–28.

Article  CAS  PubMed  Google Scholar 

Grogan RH, Kaplan SP, Cao H, Weiss RE, Degroot LJ, Simon CA, Embia OM, Angelos P, Kaplan EL, Schechter RB. A study of recurrence and death from papillary thyroid cancer with 27 years of median follow-up. Surgery. 2013;154(6):1436–46; discussion 1446-7.

Article  PubMed  Google Scholar 

Leboulleux S, Rubino C, Baudin E, Caillou B, Hartl DM, Bidart JM, Travagli JP, Schlumberger M. Prognostic factors for persistent or recurrent disease of papillary thyroid carcinoma with neck lymph node metastases and/or tumor extension beyond the thyroid capsule at initial diagnosis. J Clin Endocrinol Metab. 2005;90(10):5723–9.

Article  CAS  PubMed  Google Scholar 

Guo K, Wang Z. Risk factors influencing the recurrence of papillary thyroid carcinoma: a systematic review and meta-analysis. Int J Clin Exp Pathol. 2014;7(9):5393–403.

PubMed  PubMed Central  Google Scholar 

Pastushenko I, Blanpain C. EMT Transition States during Tumor Progression and Metastasis. Trends Cell Biol. 2019;29(3):212–26.

Article  CAS  PubMed  Google Scholar 

Lamouille S, Xu J, Derynck R. Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2014;15(3):178–96.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Morris HT, Machesky LM. Actin cytoskeletal control during epithelial to mesenchymal transition: focus on the pancreas and intestinal tract. Br J Cancer. 2015;112(4):613–20.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gao H, Bai P, Xiao L, Shen M, Yu Q, Lei Y, Huang W, Lin X, Zheng X, Wei T, et al. Mediator complex subunit 16 is down-regulated in papillary thyroid cancer, leading to increased transforming growth factor-β signaling and radioiodine resistance. J Biol Chem. 2020;295(31):10726–40.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maekawa H, Schiebel E. CLIP-170 family members: a motor-driven ride to microtubule plus ends. Dev Cell. 2004;6(6):746–8.

Article  CAS  PubMed  Google Scholar 

Suzuki K, Takahashi K. Regulation of lamellipodia formation and cell invasion by CLIP-170 in invasive human breast cancer cells. Biochem Biophys Res Commun. 2008;368(2):199–204.

Article  CAS  PubMed  Google Scholar 

Hu Y, Xie Q, Wu X, Liu W, Li D, Li C, Zhao W, Chen L, Zheng Z, Li G, et al. Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration. Cell Death Dis. 2022;13(10):856.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li D, Sun X, Zhang L, Yan B, Xie S, Liu R, Liu M, Zhou J. Histone deacetylase 6 and cytoplasmic linker protein 170 function together to regulate the motility of pancreatic cancer cells. Protein Cell. 2014;5(3):214–23.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ye F, Gao H, Xiao L, Zuo Z, Liu Y, Zhao Q, Chen H, Feng W, Fu B, Sun L, et al. Whole exome and target sequencing identifies MAP2K5 as novel susceptibility gene for familial non-medullary thyroid carcinoma. Int J Cancer. 2019;144(6):1321–30.

Article  CAS  PubMed  Google Scholar 

Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho-Simões M, Tallini G, et al. Overview of the 2022 WHO classification of thyroid neoplasms. Endocr Pathol. 2022;33(1):27–63.

Article  PubMed  Google Scholar 

Sun X, Li D, Yang Y, Ren Y, Li J, Wang Z, Dong B, Liu M, Zhou J. Microtubule-binding protein CLIP-170 is a mediator of paclitaxel sensitivity. J Pathol. 2012;226(4):666–73.

Article  CAS  PubMed  Google Scholar 

Mouron S, Bueno MJ, Lluch A, Manso L, Calvo I, Cortes J, Garcia-Saenz JA, Gil-Gil M, Martinez-Janez N, Apala JV, et al. Phosphoproteomic analysis of neoadjuvant breast cancer suggests that increased sensitivity to paclitaxel is driven by CDK4 and filamin A. Nat Commun. 2022;13(1):7529.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li L, Wen Z, Kou N, Liu J, Jin D, Wang L, Wang F, Gao L. LIS1 interacts with CLIP170 to promote tumor growth and metastasis via the Cdc42 signaling pathway in salivary gland adenoid cystic carcinoma. Int J Oncol. 2022;61(4):129.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun X, Li F, Dong B, Suo S, Liu M, Li D, Zhou J. Regulation of tumor angiogenesis by the microtubule-binding protein CLIP-170. Protein Cell. 2013;4(4):266–76.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Villanueva J, Gimenez-Molina Y, Viniegra S, Gutiérrez LM. F-actin cytoskeleton and the fate of organelles in chromaffin cells. J Neurochem. 2016;137(6):860–6.

Article  CAS  PubMed  Google Scholar 

Chesarone MA, Goode BL. Actin nucleation and elongation factors: mechanisms and interplay. Curr Opin Cell Biol. 2009;21(1):28–37.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Henty-Ridilla JL, Rankova A, Eskin JA, Kenny K, Goode BL. Accelerated actin filament polymerization from microtubule plus ends. Science. 2016;352(6288):1004–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chanez B, Ostacolo K, Badache A, Thuault S. EB1 restricts breast cancer cell invadopodia formation and matrix proteolysis via FAK. Cells. 2021;10(2):388.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stylianou A, Gkretsi V, Stylianopoulos T. Transforming growth factor-β modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion. Biochim Biophys Acta Gen Subj. 2018;1862(7):1537–46.

Article  CAS  PubMed  Google Scholar 

Ueda Y, Wang S, Dumont N, Yi JY, Koh Y, Arteaga CL. Overexpression of HER2 (erbB2) in human breast epithelial cells unmasks transforming growth factor beta-induced cell motility. J Biol Chem. 2004;279(23):24505–13.

Article  CAS  PubMed  Google Scholar 

留言 (0)

沒有登入
gif