Libby P, Ridker PM, Hansson GK. Inflammation in atherosclerosis: from pathophysiology to practice. J Am Coll Cardiol. 2009;54:2129–38.
Article CAS PubMed PubMed Central Google Scholar
Libby P. The changing landscape of atherosclerosis. Nature. 2021;592:524–33.
Article CAS PubMed Google Scholar
Ozawa K, Muller MA, Varlamov O, Tavori H, Packwood W, Mueller PA, Xie A, Ruggeri Z, Chung D, Lopez JA, Lindner JR. Proteolysis of Von Willebrand factor influences endothelial activation and vascular compliance in atherosclerosis. JACC Basic Transl Sci. 2020;5:1017–28.
Article PubMed PubMed Central Google Scholar
Wolf D, Ley K. Immunity and inflammation in atherosclerosis. Circ Res. 2019;124:315–27.
Article CAS PubMed PubMed Central Google Scholar
Stone GW, Maehara A, Lansky AJ, de Bruyne B, Cristea E, Mintz GS, Mehran R, McPherson J, Farhat N, Marso SP, et al. A prospective natural-history study of coronary atherosclerosis. N Engl J Med. 2011;364:226–35.
Article CAS PubMed Google Scholar
Dutta P, Courties G, Wei Y, Leuschner F, Gorbatov R, Robbins CS, Iwamoto Y, Thompson B, Carlson AL, Heidt T, et al. Myocardial infarction accelerates atherosclerosis. Nature. 2012;487:325–9.
Article CAS PubMed PubMed Central Google Scholar
Fang L, Moore XL, Dart AM, Wang LM. Systemic inflammatory response following acute myocardial infarction. J Geriatr Cardiol. 2015;12:305–12.
CAS PubMed PubMed Central Google Scholar
Ong SB, Hernandez-Resendiz S, Crespo-Avilan GE, Mukhametshina RT, Kwek XY, Cabrera-Fuentes HA, Hausenloy DJ. Inflammation following acute myocardial infarction: multiple players, dynamic roles, and novel therapeutic opportunities. Pharmacol Ther. 2018;186:73–87.
Article CAS PubMed PubMed Central Google Scholar
Moccetti F, Brown E, Xie A, Packwood W, Qi Y, Ruggeri Z, Shentu W, Chen J, Lopez JA, Lindner JR. Myocardial infarction produces sustained proinflammatory endothelial activation in remote arteries. J Am Coll Cardiol. 2018;72:1015–26.
Article CAS PubMed PubMed Central Google Scholar
Kang J, Jeon KH, Kim SW, Park JJ, Yoon CH, Suh JW, Cho YS, Youn TJ, Chae IH, Choi DJ. Evolution of nonculprit coronary atherosclerotic plaques assessed by serial virtual histology intravascular ultrasound in patients with ST-segment elevation myocardial infarction and chronic total occlusion. Coron Artery Dis. 2016;27:650–7.
Article PubMed PubMed Central Google Scholar
Liu Y, Davidson BP, Yue Q, Belcik T, Xie A, Inaba Y, McCarty OJ, Tormoen GW, Zhao Y, Ruggeri ZM, et al. Molecular imaging of inflammation and platelet adhesion in advanced atherosclerosis effects of antioxidant therapy with NADPH oxidase inhibition. Circ Cardiovasc Imaging. 2013;6:74–82.
Shim CY, Liu YN, Atkinson T, Xie A, Foster T, Davidson BP, Treible M, Qi Y, Lopez JA, Munday A, et al. Molecular Imaging of Platelet-Endothelial Interactions and Endothelial Von Willebrand Factor in early and mid-stage atherosclerosis. Circ Cardiovasc Imaging. 2015;8:e002765.
Chen J, Fu X, Wang Y, Ling M, McMullen B, Kulman J, Chung DW, Lopez JA. Oxidative modification of Von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13. Blood. 2010;115:706–12.
Article CAS PubMed PubMed Central Google Scholar
Weber C. Platelets and chemokines in atherosclerosis: partners in crime. Circ Res. 2005;96:612–6.
Article CAS PubMed Google Scholar
Rondina MT, Weyrich AS, Zimmerman GA. Platelets as cellular effectors of inflammation in vascular diseases. Circ Res. 2013;112:1506–19.
Article CAS PubMed PubMed Central Google Scholar
Wu MD, Atkinson TM, Lindner JR. Platelets and Von Willebrand factor in atherogenesis. Blood. 2017;129:1415–9.
Article CAS PubMed PubMed Central Google Scholar
Chen J, Reheman A, Gushiken FC, Nolasco L, Fu X, Moake JL, Ni H, Lopez JA. N-acetylcysteine reduces the size and activity of Von Willebrand factor in human plasma and mice. J Clin Invest. 2011;121:593–603.
Article CAS PubMed PubMed Central Google Scholar
Garland KS, Reitsma SE, Shirai T, Zilberman-Rudenko J, Tucker EI, Gailani D, Gruber A, McCarty OJT, Puy C. Removal of the C-Terminal domains of ADAMTS13 by activated coagulation factor XI induces platelet adhesion on endothelial cells under Flow conditions. Front Med (Lausanne). 2017;4:232.
Kaufmann BA, Carr CL, Belcik JT, Xie A, Yue Q, Chadderdon S, Caplan ES, Khangura J, Bullens S, Bunting S, Lindner JR. Molecular imaging of the initial inflammatory response in atherosclerosis: implications for early detection of disease. Arterioscler Thromb Vasc Biol. 2010;30:54–9.
Article CAS PubMed Google Scholar
Powell-Braxton L, Veniant M, Latvala RD, Hirano KI, Won WB, Ross J, Dybdal N, Zlot CH, Young SG, Davidson NO. A mouse model of human familial hypercholesterolemia: markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet. Nat Med. 1998;4:934–8.
Article CAS PubMed Google Scholar
Chen J, Ling M, Fu X, Lopez JA, Chung DW. Simultaneous exposure of sites in Von Willebrand factor for glycoprotein ib binding and ADAMTS13 cleavage: studies with ristocetin. Arterioscler Thromb Vasc Biol. 2012;32:2625–30.
Article CAS PubMed Google Scholar
Ngo ATP, Jordan KR, Mueller PA, Hagen MW, Reitsma SE, Puy C, Revenko AS, Lorentz CU, Tucker EI, Cheng Q, et al. Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low-density lipoprotein receptor-deficient mice. J Thromb Haemost. 2021;19:1001–17.
Article CAS PubMed PubMed Central Google Scholar
Ozawa K, Packwood W, Varlamov O, Qi Y, Xie A, Wu MD, Ruggeri Z, Lopez JA, Lindner JR. Molecular Imaging of VWF (Von Willebrand factor) and platelet adhesion in Postischemic impaired Microvascular Reflow. Circ Cardiovasc Imaging. 2018;11:e007913.
Article PubMed PubMed Central Google Scholar
McCarty OJ, Conley RB, Shentu W, Tormoen GW, Zha D, Xie A, Qi Y, Zhao Y, Carr C, Belcik T, et al. Molecular imaging of activated Von Willebrand factor to detect high-risk atherosclerotic phenotype. JACC Cardiovasc Imaging. 2010;3:947–55.
Article PubMed PubMed Central Google Scholar
Kaufmann BA, Sanders JM, Davis C, Xie A, Aldred P, Sarembock IJ, Lindner JR. Molecular imaging of inflammation in atherosclerosis with targeted ultrasound detection of vascular cell adhesion molecule-1. Circulation. 2007;116:276–84.
Article CAS PubMed Google Scholar
Lindner JR, Song J, Christiansen J, Klibanov AL, Xu F, Ley K. Ultrasound assessment of inflammation and renal tissue injury with microbubbles targeted to P-selectin. Circulation. 2001;104:2107–12.
Article CAS PubMed Google Scholar
Toma I, McCaffrey TA. Transforming growth factor-beta and atherosclerosis: interwoven atherogenic and atheroprotective aspects. Cell Tissue Res. 2012;347:155–75.
Article CAS PubMed Google Scholar
Chen PY, Qin L, Li G, Wang Z, Dahlman JE, Malagon-Lopez J, Gujja S, Cilfone NA, Kauffman KJ, Sun L, et al. Endothelial TGF-beta signalling drives vascular inflammation and atherosclerosis. Nat Metab. 2019;1:912–26.
Article CAS PubMed PubMed Central Google Scholar
Abbas AE, Fortuin FD, Schiller NB, Appleton CP, Moreno CA, Lester SJ. A simple method for noninvasive estimation of pulmonary vascular resistance. J Am Coll Cardiol. 2003;41:1021–7.
Ueland T, Otterdal K, Lekva T, Halvorsen B, Gabrielsen A, Sandberg WJ, Paulsson-Berne G, Pedersen TM, Folkersen L, Gullestad L, et al. Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis. Arterioscler Thromb Vasc Biol. 2009;29:1228–34.
Article CAS PubMed Google Scholar
Massberg S, Brand K, Gruner S, Page S, Muller E, Muller I, Bergmeier W, Richter T, Lorenz M, Konrad I, et al. A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation. J Exp Med. 2002;196:887–96.
Article CAS PubMed PubMed Central Google Scholar
Theilmeier G, Michiels C, Spaepen E, Vreys I, Collen D, Vermylen J, Hoylaerts MF. Endothelial von Willebrand factor recruits platelets to atherosclerosis-prone sites in response to hypercholesterolemia. Blood. 2002;99:4486–93.
Article CAS PubMed Google Scholar
Methia N, Andre P, Denis CV, Economopoulos M, Wagner DD. Localized reduction of atherosclerosis in Von Willebrand factor-deficient mice. Blood. 2001;98:1424–8.
留言 (0)