Vitamin D and reproductive disorders: a comprehensive review with a focus on endometriosis

Huhtakangas JA, Olivera CJ, Bishop JE, Zanello LP, Norman AW. The vitamin D receptor is present in caveolae-enriched plasma membranes and binds 1α, 25 (OH) 2-vitamin D3 in vivo and in vitro. Mol Endocrinol. 2004;18:2660–71.

Article  CAS  PubMed  Google Scholar 

Kahlon Simon-Collins M, Nylander E, Segars J, Singh BBK. A systematic review of vitamin D and endometriosis: role in pathophysiology, diagnosis, treatment, and prevention. F&S Rev. 2022;4:1–14.

Article  Google Scholar 

Nandi A, Sinha N, Ong E, Sonmez H, Poretsky L. Is there a role for vitamin D in human reproduction? 2016;25:15–28.

Chen Y, Zhi X. Roles of vitamin D in Reproductive systems and assisted Reproductive Technology. Endocrinology. 2020;161:bqaa023.

Article  PubMed  Google Scholar 

Grundmann M, von Versen-Höynck F. Vitamin D - roles in women’s reproductive health? Reprod Biol Endocrinol. 2011;9:146.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tartagni M, Matteo M, Baldini D, Tartagni MV, Alrasheed H, De Salvia MA, et al. Males with low serum levels of vitamin D have lower pregnancy rates when ovulation induction and timed intercourse are used as a treatment for infertile couples: results from a pilot study. Reprod Biol Endocrinol. 2015;13:127.

Article  PubMed  PubMed Central  Google Scholar 

Hasan HA, Barber TM, Cheaib S, Coussa A. Preconception Vitamin D Level and in Vitro fertilization: pregnancy outcome. Endocr Pract. 2023;29:235–9.

Article  PubMed  Google Scholar 

Ashour H, Gamal SM, Sadek NB, Rashed LA, Hussein RE, Kamar SS et al. Vitamin D supplementation improves uterine receptivity in a rat model of vitamin D Deficiency: a possible role of HOXA-10/FKBP52 Axis. Front Physiol. 2021;12:744548.

Article  PubMed  PubMed Central  Google Scholar 

Shin JS, Choi MY, Longtine MS, Nelson DM. Vitamin D effects on pregnancy and the placenta. Placenta. 2010;31:1027–34.

Article  CAS  PubMed  PubMed Central  Google Scholar 

McDonnell SL, Baggerly KA, Baggerly CA, Aliano JL, French CB, Baggerly LL, et al. Maternal 25(OH)D concentrations ≥ 40 ng/mL associated with 60% lower preterm birth risk among general obstetrical patients at an urban medical center. PLoS ONE. 2017;12:e0180483.

Article  PubMed  PubMed Central  Google Scholar 

Razavi M, Jamilian M, Samimi M, Afshar Ebrahimi F, Taghizadeh M, Bekhradi R, et al. The effects of vitamin D and omega-3 fatty acids co-supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in patients with gestational diabetes. Nutr Metab (Lond). 2017;14:80.

Article  PubMed  Google Scholar 

Wagner CL, Taylor SN, Johnson DD, Hollis BW. The role of vitamin D in pregnancy and lactation: emerging concepts. Womens Health (Lond Engl). 2012;8:323–40.

Article  CAS  PubMed  Google Scholar 

Chu J, Gallos I, Tobias A, Robinson L, Kirkman-Brown J, Dhillon-Smith R, et al. Vitamin D and assisted reproductive treatment outcome: a prospective cohort study. Reprod Health. 2019;16:106.

Article  PubMed  PubMed Central  Google Scholar 

Roth DE, Leung M, Mesfin E, Qamar H, Watterworth J, Papp E. Vitamin D supplementation during pregnancy: state of the evidence from a systematic review of randomised trials. BMJ. 2017;359:j5237.

Article  PubMed  PubMed Central  Google Scholar 

Chapron C, Marcellin L, Borghese B, Santulli P. Rethinking mechanisms, diagnosis and management of endometriosis. Nat Rev Endocrinol. 2019;15:666–82.

Article  PubMed  Google Scholar 

Vercellini P, Viganò P, Somigliana E, Fedele L. Endometriosis: pathogenesis and treatment. Nat Rev Endocrinol. 2014;10:261–75.

Article  CAS  PubMed  Google Scholar 

Kolahdouz-Mohammadi R, Shidfar F, Khodaverdi S, Arablou T, Heidari S, Rashidi N, et al. Resveratrol treatment reduces expression of MCP-1, IL‐6, IL‐8 and RANTES in endometriotic stromal cells. J Cell Mol Med. 2021;25:1116–27.

Article  CAS  PubMed  Google Scholar 

Zondervan KT, Becker CM, Koga K, Missmer SA, Taylor RN. Viganò P. Endometriosis. Nat Rev Dis Prim. 2018;4:9.

Article  PubMed  Google Scholar 

Falcone AKR& T. Treatment strategies for endometriosis. Expert Opin Pharmacother. 2008;9:243–55.

Article  Google Scholar 

Delbandi A-A, Torab M, Abdollahi E, Khodaverdi S, Rokhgireh S, Moradi Z, et al. Vitamin D deficiency as a risk factor for endometriosis in Iranian women. J Reprod Immunol. 2021;143:103266.

Article  CAS  PubMed  Google Scholar 

Agic A, Xu H, Altgassen C, Noack F, Wolfler MM, Diedrich K, et al. Relative expression of 1,25-dihydroxyvitamin D3 receptor, vitamin D 1 alpha-hydroxylase, vitamin D 24-hydroxylase, and vitamin D 25-hydroxylase in endometriosis and gynecologic cancers. Reprod Sci. 2007;14:486–97.

Article  CAS  PubMed  Google Scholar 

Vuolo L, di somma C, Faggiano A, Colao A. Vitamin D and Cancer. Front Endocrinol (Lausanne). 2012;3:58.

Article  CAS  PubMed  Google Scholar 

D’Ambrosio D, Cippitelli M, Cocciolo MG, Mazzeo D, Di Lucia P, Lang R, et al. Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene. J Clin Invest. 1998;101:252–62.

Article  PubMed  PubMed Central  Google Scholar 

Baeke F, Etten E, Van, Overbergh L, Mathieu C. Vitamin D3 and the immune system: maintaining the balance in health and disease. Nutr Res Rev. 2007;20:106–18.

Article  CAS  PubMed  Google Scholar 

Colonese F, Laganà AS, Colonese E, Sofo V, Salmeri FM, Granese R, et al. The pleiotropic effects of vitamin D in gynaecological and obstetric diseases: an overview on a hot topic. Biomed Res Int. 2015;2015:986281.

Article  PubMed  PubMed Central  Google Scholar 

Mathieu C, Adorini L. The coming of age of 1,25-dihydroxyvitamin D(3) analogs as immunomodulatory agents. Trends Mol Med. 2002;8:174–9.

Article  CAS  PubMed  Google Scholar 

Heidari S, Kolahdouz-Mohammadi R, Khodaverdi S, Mohammadi T, Delbandi A-A. Changes in MCP-1, HGF, and IGF-1 expression in endometrial stromal cells, PBMCs, and PFMCs of endometriotic women following 1,25(OH)2D3 treatment. J Cell Mol Med. 2022;n/a n/a.

Delbandi A-A, Mahmoudi M, Shervin A, Zarnani A-H. 1,25-Dihydroxy vitamin D3 modulates endometriosis-related features of human endometriotic stromal cells. Am J Reprod Immunol. 2016;75:461–73.

Article  CAS  PubMed  Google Scholar 

Holick MF. Vitamin D: a D-Lightful health perspective. Nutr Rev. 2008;66 suppl2:S182–94.

Article  Google Scholar 

Kumar R. Metabolism of 1,25-dihydroxyvitamin D3. Physiol Rev. 1984;64:478–504.

Article  CAS  PubMed  Google Scholar 

Soto JR, Anthias C, Madrigal A, Snowden JA. Insights Into the Role of Vitamin D as a Biomarker in Stem Cell Transplantation. Front Immunol. 2020;11:500910.

Article  Google Scholar 

Strushkevich N, Usanov SA, Plotnikov AN, Jones G, Park H-W. Structural analysis of CYP2R1 in complex with vitamin D3. J Mol Biol. 2008;380:95–106.

Article  CAS  PubMed  Google Scholar 

Holick MF, Vitamin D. A millenium perspective. J Cell Biochem. 2003;88:296–307.

Article  CAS  PubMed  Google Scholar 

Prietl B, Treiber G, Pieber TR, Amrein K. Vitamin D and Immune function. Nutrients. 2013;5:2502–21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jones G, Prosser DE, Kaufmann M. Cytochrome P450-mediated metabolism of vitamin D. J Lipid Res. 2014;55:13–31.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Reichel H, Norman AW. Systemic Effects of Vitamin D. Annu Rev Med. 1989;1989(40 Volume 40):71–8.

Article  Google Scholar 

Deeb KK, Trump DL, Johnson CS. Vitamin D signalling pathways in cancer: potential for anticancer therapeutics. Nat Rev cancer. 2007;7:684–700.

Article  CAS  PubMed  Google Scholar 

Balvers MGJ, Brouwer-Brolsma EM, Endenburg S, De Groot LC, Kok FJ, Gunnewiek JK. Recommended intakes of vitamin D to optimise health, associated circulating 25-hydroxyvitamin D concentrations, and dosing regimens to treat deficiency: workshop report and overview of current literature. J Nutr Sci. 2015;4:e23.

Article  PubMed  PubMed Central  Google Scholar 

Benedik E. Sources of vitamin D for humans. Int J Vitam Nutr Res. 2021.

Holick MF, Smith E, Pincus S. Skin as the site of vitamin D synthesis and target tissue for 1, 25-dihydroxyvitamin D3: use of calcitriol (1, 25-dihydroxyvitamin D3) for treatment of psoriasis. Arch Dermatol. 1987;123:1677–a1683.

Article  CAS  PubMed  Google Scholar 

Lips P. Vitamin D physiology. Prog Biophys Mol Biol. 2006;92:4–8.

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