Martin SA, Atlantis E, Lange K, et al, members of the Florey Adelaide Male Ageing Study. Predictors of sexual dysfunction incidence and remission in men. J Sex Med 2014; 11:1136–47.
Gades NM, Jacobson DJ, McGree ME, et al. Longitudinal evaluation of sexual function in a male cohort: the Olmsted County Study of Urinary Symptoms and Health Status among Men. J Sex Med. 2009;6:455.
NIH Consensus Conference. Impotence. NIH Consensus Development Panel on Impotence. JAMA.1993;270:83–90.
Durazzo M, Premoli A, Di Bisceglie C, Bo S, Ghigo E, Manieri C. Male sexual disturbances in liver diseases: what do we know? J Endocrinol Invest. 2010;33(7):501–5.
Article CAS PubMed Google Scholar
Tarik Kani H, Emre Sener T, Emre Aykut U, OzerDemirtas C, Keklikkiran C, Ergenc I, Fatih Demirci A, Kamil Cam H, Celikel C, Akbal C, Duman D. Causes of erectile dysfunction in non-alcoholic fatty liver disease. Hepatol Forum. 2021;2(2):60–3.
PubMed PubMed Central Google Scholar
Shiha G, Korenjak M, Eskridge W, Casanovas T, Velez-Moller P, Högström S, Richardson B, Munoz C, Sigurðardóttir S, Coulibaly A, Milan M, Bautista F, Leung NWY, Mooney V, Obekpa S, Bech E, Polavarapu N, Hamed AE, Radiani T, Purwanto E, Bright B, Ali M, Dovia CK, McColaugh L, Koulla Y, Dufour JF, Soliman R, Eslam M. Redefining fatty liver disease: an international patient perspective. Lancet Gastroenterol Hepatol. 2021;6(1):73–9.
Idilman IS, Ozdeniz I, Karcaaltincaba M. Hepatic Steatosis: Etiology, Patterns, and Quantification. Semin Ultrasound CT MR. 2016;37(6):501–10.
Williams CD, Stengel J, Asike MI, Torres DM, Shaw J, Contreras M, et al. Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study. Gastroenterology. 2011;140(1):124–31.
Ahmed A, Wong RJ, Harrison SA. Nonalcoholicfattyliverdisease review: diagnosis, treatment, and outcomes. Clin Gastroenterol Hepatol. 2015;13(12):2062–70.
Hawksworth DJ, Burnett AL. Nonalcoholic fatty liver disease, male sexual dysfunction, and infertility: common links, common problems. Sexual Med Rev. 2020;8(2):274–85.
Haas JT, Francque S, Staels B. Pathophysiology and mechanisms of nonalcoholic fatty liver disease. Annu Rev Physiol. 2016;78(1):181–205.
Article CAS PubMed Google Scholar
Corona DG, Vena W, Pizzocaro A, Rastrelli G, Sparano C, Sforza A, Vignozzi L, Maggi M. Metabolic syndrome and erectile dysfunction: a systematic review and meta-analysis study. J Endocrinol Invest. 2023;46(11):2195–211.
Article CAS PubMed Google Scholar
Romano L, Pellegrino R, Sciorio C, Barone B, Gravina AG, Santonastaso A, Mucherino C, Astretto S, Napolitano L, Aveta A, Pandolfo SD, Loizzo D, Del Giudice F, Ferro M, Imbimbo C, Romano M, Crocetto F. Erectile and sexual dysfunction in male and female patients with celiac disease: A cross-sectional observational study. Andrology. 2022;10(5):910–918. https://doi.org/10.1111/andr.13186. PMID: 35419983; PMCID: PMC9324123.
Cantone E, Massanova M, Crocetto F, Barone B, Esposito F, Arcaniolo D, Corlianò F, Romano L, Motta G, Celia A. The relationship between obstructive sleep apnoea and erectile dysfunction: An underdiagnosed link? A prospective cross-sectional study. Andrologia. 2022;54(9):e14504. https://doi.org/10.1111/and.14504. PMID: 35817418; PMCID: PMC9539465.
Ralph DJ. Normal erectile function. Clin Cornerstone. 2005;7(1):13–7.
Raddino R, Caretta G, Teli M, Bonadei I, Robba D, Zanini G, Madureri A, Nodari S, Dei CL. Nitric oxide and cardiovascular risk factors. Heart Int. 2007;3(1–2):1826186807003001–203.
Ahluwalia A, Gladwin M, Coleman GD, Hord N, Howard G, Kim-Shapiro DB, Lajous M, Larsen FJ, Lefer DJ, McClure LA, Nolan BT. Dietary nitrate and the epidemiology of cardiovascular disease: report from a National Heart, Lung, and Blood Institute Workshop. J Am Heart Assoc. 2016;5(7):e003402.
Article PubMed PubMed Central Google Scholar
Luiking YC, Engelen MP, Deutz NE. Regulation of nitric oxide production in health and disease. Curr Opin Clin Nutr Metab Care. 2010;13(1):97.
Article CAS PubMed PubMed Central Google Scholar
Razny U, Kiec-Wilk B, Wator L, Polus A, Dyduch G, Solnica B, Malecki M, Tomaszewska R, Cooke JP, Dembinska-Kiec A. Increased nitric oxide availability attenuates high fat diet metabolic alterations and gene expression associated with insulin resistance. Cardiovasc Diabetol. 2011;10(1):1–4.
Saroukhani S, Emami-Parsa M, Modabbernia A, Ashrafi M, Farokhnia M, Hajiaghaee R, Akhondzadeh S. Aspirin for treatment of lithium-associated sexual dysfunction in men: randomized double-blind placebo-controlled study. Bipolar Disord. 2013;15(6):650–6.
Article CAS PubMed Google Scholar
Nozaki Y, Fujita K, Wada K, et al. Deficiency of eNOS exacerbates early-stage NAFLD pathogenesis by changing the fat distribution. BMC Gastroenterol. 2015;15:177.
Article PubMed PubMed Central Google Scholar
Persico M, Masarone M, Damato A, et al. Non-alcoholic fatty liver disease and eNOS dysfunction in humans. BMC Gastroenterol. 2017;17:35.
Article PubMed PubMed Central Google Scholar
Kumar KG, Trevaskis JL, Lam DD, Sutton GM, Koza RA, Chouljenko VN, et al. Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism. Cell Metab. 2008;8(6):468–81.
Article CAS PubMed PubMed Central Google Scholar
Kutlu O, Altun Ö, Dikker O, Aktaş Ş, Özsoy N, Arman Y, Özgün Çil E, Özcan M, AydınYoldemir Ş, Akarsu M, Toprak İD, Kırna K, Kutlu Y, Toprak Z, Eruzun H, Tükek T. Serum Adropin Levels Are Reduced in Adult Patients with Nonalcoholic Fatty Liver Disease. Med PrincPract. 2019;28(5):463–9.
Yilmaz M, Odabas O, Karaaslan M, Guler OF, Toprak T, Bicer S, Tonyali S. Predicting risk of erectile dysfunction in patients with nonalcoholic fatty liver disease. Andrologia. 2021;53(7):e14091.
Article CAS PubMed Google Scholar
Duman DG, Biçakci E, Çelikel ÇA, Akbal C. Nonalcoholic Fatty Liver Disease is Associated with Erectile Dysfunction: A Prospective Pilot Study. J Sex Med. 2016;13(3):383–8.
World Medical Association. World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. JAMA. 2013;310(20):2191–4.
Ferraioli G, Monteiro LBS. Ultrasound-based techniques for the diagnosis of liver steatosis. World J Gastroenterol. 2019;25(40):6053.
Article PubMed PubMed Central Google Scholar
Eslam M, Newsome PN, Sarin SK, Anstee QM, Targher G, Romero-Gomez M, et al. A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement. J Hepatol. 2020;73(1): 202–209.
Shamloul R, Ghanem H, Abou-Zeid A. Validity of the Arabic version of the sexual health inventory for men among Egyptians. Int J Impot Res. 2004;16(5):452–5.
Article CAS PubMed Google Scholar
Spitzer RL, Kroenke K, Williams JB, et al. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166(10):1092–7.
Sawaya H, Atoui M, Hamadeh A, Zeinoun P, Nahas Z. Adaptation and initial validation of the Patient Health Questionnaire–9 (PHQ-9) and the Generalized Anxiety Disorder–7 Questionnaire (GAD-7) in an Arabic speaking Lebanese psychiatric outpatient sample. Psychiatry Res. 2016;30(239):245–52.
Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606–13.
Article CAS PubMed PubMed Central Google Scholar
Kawaguchi T, Tsutsumi T, Nakano D, Torimura T. MAFLD: Renovation of clinical practice and disease awareness of fatty liver. Hepatol Res. 2022;52(5):422–32.
Cobbina E, Akhlaghi F. Non-alcoholicfatty liver disease (NAFLD)–pathogenesis, classification, and effect on drug metabolizing enzymes and transporters. Drug Metab Rev. 2017;49(2):197–211.
Article CAS PubMed PubMed Central Google Scholar
Young S, Tariq R, Provenza J, Satapathy SK, Faisal K, Choudhry A, Friedman SL, Singal AK. Prevalence and profile of nonalcoholic fatty liver disease in lean adults: systematic review and Meta-Analysis. Hepatology communications. 2020;4(7):953–72.
Article CAS PubMed PubMed Central Google Scholar
Burnett AL, Lowenstein CJ, Bredt DS, et al. Nitric oxide: A physiologic mediator of penile erection. Science. 1992;257:401–3.
Article CAS PubMed Google Scholar
Burnett AL. The role of nitric oxide in erectile dysfunction: implications for medical therapy. J ClinHypertens (Greenwich). 2006;8(12 Suppl 4):53–62.
Kuloglu T, Aydin S. Immunohistochemical expressions of adropin and inducible nitric oxide synthase in renal tissues of rats with streptozotocin-induced experimental diabetes. Biotech Histochem. 2014;89:104–10.
Article CAS PubMed Google Scholar
Topuz M, Celik A, Aslantas T, Demir AK, Aydin S, Aydin S. Plasma adropin levels predict endothelial dysfunction like flow-mediated dilatation in patients with type 2 diabetes mellitus. J Investig Med. 2013;61:1161–4.
Article CAS PubMed Google Scholar
Osuna JA, Gómez-Pérez R, Arata-Bellabarba G, et al. Relationship between BMI, total testosterone, sex hormone binding-globulin, leptin, insulin and insulin resistance in obese men. Arch Androl. 2006;52:355–61.
Article CAS PubMed Google Scholar
Eguchi Y, Mizuta T, Sumida Y, et al. The pathological role of visceral fat accumulation in steatosis, inflammation, and progression of nonalcoholic fatty liver disease. J Gastroenterol. 2011;46(Suppl 1):70–8.
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