Short-term and long-term outcomes of on-pump beating-heart coronary artery bypass surgery in dialysis and non-dialysis patients: a retrospective study in a single center

The results of the present study, dialysis patients had significantly worse outcomes compared to non-dialysis patients after on-pump beating-heart CABG, including longer length of stay, higher rate of post-CABG MI, and lower survival during follow-up. However, no significant differences in in-hospital mortality, surgical complications, or revascularization rate during follow-up were observed between dialysis and non-dialysis groups. Our results show that on-pump beating-heart CABG is a safe and effective option for dialysis patients.

In the present study, no significant differences in in-hospital mortality, surgical complications, or post-CABG reintervention during follow-up was observed between dialysis and non-dialysis patients. Dialysis is known as an independent risk factor for surgical mortality after CABG [1, 3,4,5]. Our results showed on-pump beating-heart CABG could achieve comparable short-term surgical outcomes in dialysis patients as those in non-dialysis patients. Meanwhile, Chen et al. reported a higher risk for revascularization after CABG in dialysis patients than non-dialysis patients [3]. It is well-recognized that on-pump CABG ensures comprehensive revascularization [7, 8]. Our result showed that on-pump beating-heart CABG achieves good long-term revascularization also in dialysis group. These results together show that it is a safe and effective option for dialysis patients.

Our results showed that dialysis patients had a significantly longer length of stay, higher rate of MI, and poorer survival after CABG compared to non-dialysis patients. Dialysis is significantly associated with poor outcomes after cardiac surgery [1,2,3,4,5], and the risk for mortality is elevated as dialysis-dependence duration extends [1, 3]. Studies have reported that dialysis patients show significantly higher 30-day mortality, readmission rate, rates of postoperative MI or revascularization, and lower survival after CABG compared to non-dialysis patients [1,2,3,4,5]. CABG is not associated with short-term mortality but improves life expectancy of dialysis patients [5, 9, 10]. For better prognosis, more attention must be paid on dialysis patients’ postoperative conditions after CABG, including monitoring cardiovascular stability, and education of self-care for patients and caregivers.

In the present study, PD patients showed twofold higher in-hospital mortality compared to HD patients without statistically significant difference (2/12 vs. 7/115, p = 0.222) probably due to the limited sample size. Studies reported that PD patients were prone to higher in-hospital mortality than HD patients after CABG [11, 12]. Further study is needed to clarify the underlying mechanism.

留言 (0)

沒有登入
gif