do Carmo Oliveira TG et al (2021) TNF-mimetic peptide mixed with fibrin glue improves peripheral nerve regeneration. Brain Res Bull 174:53–62

Article  PubMed  Google Scholar 

Menorca RM, Fussell TS, Elfar JC (2013) Nerve physiology: mechanisms of injury and recovery. Hand Clin 29(3):317–330

Article  PubMed  PubMed Central  Google Scholar 

Campbell WW (2008) Evaluation and management of peripheral nerve injury. Clin Neurophysiol 119(9):1951–1965

Article  PubMed  Google Scholar 

Sulaiman W, Gordon T (2013) Neurobiology of peripheral nerve injury, regeneration, and functional recovery: from bench top research to bedside application. Ochsner J 13(1):100–108

PubMed  PubMed Central  Google Scholar 

Zarinfard G et al (2016) Effect of laminin on neurotrophic factors expression in schwann-like cells induced from human adipose-derived stem cells in vitro. J Mol Neurosci 60(4):465–473

Article  CAS  PubMed  Google Scholar 

Mirsky R et al (2002) Schwann cells as regulators of nerve development. J Physiol Paris 96(1–2):17–24

Article  CAS  PubMed  Google Scholar 

Madduri S, Gander B (2010) Schwann cell delivery of neurotrophic factors for peripheral nerve regeneration. J Peripher Nerv Syst 15(2):93–103

Article  CAS  PubMed  Google Scholar 

Nocera G, Jacob C (2020) Mechanisms of Schwann cell plasticity involved in peripheral nerve repair after injury. Cell Mol Life Sci 77(20):3977–3989

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ananthan S, Benoliel R (2020) Chronic orofacial pain. J Neural Transm (Vienna) 127(4):575–588

Article  PubMed  Google Scholar 

Jacquin MF, Chiaia NL, Rhoades RW (1990) Trigeminal projections to contralateral dorsal horn: central extent, peripheral origins, and plasticity. Somatosens Mot Res 7(2):153–183

Article  CAS  PubMed  Google Scholar 

Reyes-García G, Medina-Santillán R, Flores-Murrieta FJ, Caram-Salas NL, Granados-Soto V (2006) Analgesic effects of B vitamins: A review. Current Topics in Pharmacology 10(1):1–31

Gibson GE, Zhang H (2002) Interactions of oxidative stress with thiamine homeostasis promote neurodegeneration. Neurochem Int 40(6):493–504

Article  CAS  PubMed  Google Scholar 

Yang TT, Wang SJ (2009) Pyridoxine inhibits depolarization-evoked glutamate release in nerve terminals from rat cerebral cortex: a possible neuroprotective mechanism? J Pharmacol Exp Ther 331(1):244–254

Article  CAS  PubMed  Google Scholar 

Wu F et al (2019) Vitamin B(12) enhances nerve repair and improves functional recovery after traumatic brain injury by inhibiting er stress-induced neuron injury. Front Pharmacol 10:406

Article  CAS  PubMed  PubMed Central  Google Scholar 

Suzuki K et al (2017) Electrospun nanofiber sheets incorporating methylcobalamin promote nerve regeneration and functional recovery in a rat sciatic nerve crush injury model. Acta Biomater 53:250–259

Article  CAS  PubMed  Google Scholar 

Sun H et al (2012) Dexamethasone and vitamin B(12) synergistically promote peripheral nerve regeneration in rats by upregulating the expression of brain-derived neurotrophic factor. Arch Med Sci 8(5):924–930

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yazdani SO et al (2012) Effects of low level laser therapy on proliferation and neurotrophic factor gene expression of human schwann cells in vitro. J Photochem Photobiol B 107:9–13

Article  CAS  PubMed  Google Scholar 

Ziago EK et al (2017) Analysis of the variation in low-level laser energy density on the crushed sciatic nerves of rats: a morphological, quantitative, and morphometric study. Lasers Med Sci 32(2):369–378

Article  PubMed  Google Scholar 

Gigo-Benato D et al (2010) Effects of 660 and 780 nm low-level laser therapy on neuromuscular recovery after crush injury in rat sciatic nerve. Lasers Surg Med 42(9):673–682

Article  PubMed  Google Scholar 

Serafim KG et al (2012) Effects of 940 nm light-emitting diode (led) on sciatic nerve regeneration in rats. Lasers Med Sci 27(1):113–119

Article  PubMed  Google Scholar 

Alcântara CC et al (2013) Effect of low-level laser therapy (LLLT) on acute neural recovery and inflammation-related gene expression after crush injury in rat sciatic nerve. Lasers Surg Med 45(4):246–252

Article  PubMed  Google Scholar 

Zimmermann M (1983) Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16(2):109–110

Article  PubMed  Google Scholar 

Chichorro JG et al (2006) Orofacial cold hyperalgesia due to infraorbital nerve constriction injury in rats: reversal by endothelin receptor antagonists but not non-steroidal anti-inflammatory drugs. Pain 123(1–2):64–74

Article  CAS  PubMed  Google Scholar 

de Oliveira Martins D et al (2013) Laser therapy and pain-related behavior after injury of the inferior alveolar nerve: possible involvement of neurotrophins. J Neurotrauma 30(6):480–486

Article  PubMed  PubMed Central  Google Scholar 

Martins DO, Dos Santos FM, Ciena AP, Watanabe IS, de Britto LRG, Lemos JBD, Chacur M (2017) Neuropeptide expression and morphometric differences in crushed alveolar inferior nerve of rats: Effects of photobiomodulation. Lasers Med Sci 32(4):833–840. https://doi.org/10.1007/s10103-017-2181-2

Martins DO et al (2017) Neurochemical effects of photobiostimulation in the trigeminal ganglion after inferior alveolar nerve injury. J Biol Regul Homeost Agents 31(1):147–152

CAS  PubMed  Google Scholar 

de Freitas Rodrigues A et al (2020) The effectiveness of photobiomodulation in the management of temporomandibular pain sensitivity in rats: behavioral and neurochemical effects. Lasers Med Sci 35(2):447–453

Article  PubMed  Google Scholar 

Kopruszinski CM, Reis RC, Chichorro JG (2012) B vitamins relieve neuropathic pain behaviors induced by infraorbital nerve constriction in rats. Life Sci 91(23–24):1187–1195

Article  CAS  PubMed  Google Scholar 

Kopruszinski CM et al (2015) Vitamin B complex attenuated heat hyperalgesia following infraorbital nerve constriction in rats and reduced capsaicin in vivo and in vitro effects. Eur J Pharmacol 762:326–332

Article  CAS  PubMed  Google Scholar 

Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248–254

Article  CAS  PubMed  Google Scholar 

Snedecor GW, Sokal RR, Rohlf FJ (1946) Statistical methods Biometry. 4 ed.Ames, ed. W.H. Freeman & Co., New York: Owa State University Press. p.859

Scalabrino G, Peracchi M (2006) New insights into the pathophysiology of cobalamin deficiency. Trends Mol Med 12(6):247–254

Article  CAS  PubMed  Google Scholar 

Fujii A, Matsumoto H, Yamamoto H (1996) Effect of vitamin B complex on neurotransmission and neurite outgrowth. Gen Pharmacol 27(6):995–1000

Article  CAS  PubMed  Google Scholar 

Marques DP, Chacur M, Martins DO (2023) Photobiomodulation and vitamin B treatment alleviate both thermal and mechanical orofacial pain in rats. Photochem Photobiol Sci 22(10):2315–2327. https://doi.org/10.1007/s43630-023-00452-y

Martins DO, Marques DP, Venega RAG, Chacur M (2020) Photobiomodulation and B vitamins administration produces antinociception in an orofacial pain model through the modulation of glial cells and cytokines expression. Brain Behav Immun Health 2:100040. https://doi.org/10.1016/j.bbih.2020.100040

Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME (1999) Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 286(5443):1358–62. https://doi.org/10.1126/science.286.5443.1358

Markus A, Zhong J, Snider WD (2002) Raf and akt mediate distinct aspects of sensory axon growth. Neuron 35(1):65–76. https://doi.org/10.1016/s0896-6273(02)00752-3

Zhu D et al (2005) N-methyl-D-aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal-regulated kinase pathway. J Neurosci Res 80(1):104–113

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aonurm-Helm A et al (2010) NCAM-mimetic, FGL peptide, restores disrupted fibroblast growth factor receptor (FGFR) phosphorylation and FGFR mediated signaling in neural cell adhesion molecule (NCAM)-deficient mice. Brain Res 1309:1–8

Article  CAS  PubMed  Google Scholar 

Hsieh YL et al (2012) Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury: Possible involvements in hypoxia-inducible factor 1α (HIF-1α). J Comp Neurol 520(13):2903–2916

Article  CAS  PubMed  Google Scholar 

Gomes LE, Dalmarco EM, Andre ES (2012) The brain-derived neurotrophic factor, nerve growth factor, neurotrophin-3, and induced nitric oxide synthase expressions after low-level laser therapy in an axonotmesis experimental model. Photomed Laser Surg 30(11):642–647

Article  CAS  PubMed  Google Scholar 

Yu WM, Yu H, Chen ZL (2007) Laminins in peripheral nerve development and muscular dystrophy. Mol Neurobiol 35(3):288–297

Article  CAS  PubMed  Google Scholar 

Yu WM et al (2009) Laminin is required for Schwann cell morphogenesis. J Cell Sci 122(Pt 7):929–936

Article  CAS