Outcome data for renal denervation: craving the unattainable?

Barbato E, Azizi M, Schmieder RE, Lauder L, Böhm M, Brouwers S, et al. Renal denervation in the management of hypertension in adults. A clinical consensus statement of the ESC Council on Hypertension and the European Association of Percutaneous Cardiovascular Interventions (EAPCI). EuroIntervention. 2023;18:1227–43.

PubMed  PubMed Central  Google Scholar 

Mancia G, Kreutz R, Brunstrom M, Burnier M, Grassi G, Januszewicz A, et al. 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension: Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA). J Hypertens. 2023;41:1874–2071.

Article  CAS  PubMed  Google Scholar 

Wang J, Sun N, Ge J, Jiang H, Yin Y, Chen M, et al. Rationale and Design of Sympathetic Mapping/Ablation of Renal Nerves Trial (SMART) for the Treatment of Hypertension: a Prospective, Multicenter, Single-blind, Randomized and Sham Procedure-Controlled Study. J Cardiovasc Transl Res. 2023;16:358–70.

Article  PubMed  Google Scholar 

Haider SA, Wagener M, Iqbal T, Shazad S, Del Sole PA, Leahy N, et al. Does renal denervation require cardiovascular outcome-driven data? Hypertens Res. 2024. https://doi.org/10.1038/s41440-024-01598-7. Online ahead of print.

Weintraub WS, Luscher TF, Pocock S. The perils of surrogate endpoints. Eur Heart J. 2015;36:2212–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nazarzadeh M, Bidel Z, Canoy D, Copland E, Wamil M, Majert J, et al. Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis. Lancet. 2021;398:1803–10.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Desai M, Stockbridge N, Temple R. Blood pressure as an example of a biomarker that functions as a surrogate. AAPS J. 2006;8:E146–52.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fengler K, Reimann P, Rommel KP, Kresoja KP, Blazek S, Unterhuber M, et al. Comparison of long-term outcomes for responders versus non-responders following renal denervation in resistant hypertension. J Am Heart Assoc. 2021;10:e022429.

Article  PubMed  PubMed Central  Google Scholar 

Mahfoud F, Mancia G, Schmieder RE, Ruilope L, Narkiewicz K, Schlaich M, et al. Cardiovascular risk reduction after renal denervation according to time in therapeutic systolic blood pressure range. J Am Coll Cardiol. 2022;80:1871–80.

Article  CAS  PubMed  Google Scholar 

Parving HH, Brenner BM, McMurray JJ, de Zeeuw D, Haffner SM, Solomon SD, et al. Cardiorenal end points in a trial of aliskiren for type 2 diabetes. N. Engl J Med. 2012;367:2204–13.

Article  CAS  PubMed  Google Scholar 

Lauder L, Mahfoud F, Azizi M, Bhatt DL, Ewen S, Kario K, et al. Hypertension management in patients with cardiovascular comorbidities. Eur Heart J. 2022;44:2066–77.

Article  Google Scholar 

Lauder L, Ewen S, Glasmacher J, Lammert F, Reith W, Schreiber N, et al. Drug adherence and psychosocial characteristics of patients presenting with hypertensive urgency at the emergency department. J Hypertens. 2021;39:1697–704.

Article  CAS  PubMed  Google Scholar 

Hohl M, Lauder L, Sevimli O, Tokcan M, Wagmann L, Gotzinger F, et al. Efficacy of antihypertensive drugs of different classes after renal denervation in spontaneously hypertensive rats. Hypertension. 2023;80:e90–e100.

Article  CAS  PubMed  Google Scholar 

Staplin N, de la Sierra A, Ruilope LM, Emberson JR, Vinyoles E, Gorostidi M, et al. Relationship between clinic and ambulatory blood pressure and mortality: an observational cohort study in 59 124 patients. Lancet. 2023;401:2041–50.

Article  PubMed  Google Scholar 

Balshem H, Helfand M, Schunemann HJ, Oxman AD, Kunz R, Brozek J, et al. GRADE guidelines: 3. Rating the quality of evidence. J Clin Epidemiol. 2011;64:401–6.

Article  PubMed  Google Scholar 

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