Bray, F., et al. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians. https://doi.org/10.3322/caac.21492

Article  PubMed  Google Scholar 

Dekker, E., et al. (2019). Colorectal cancer. The Lancet. https://doi.org/10.1016/S0140-6736(19)32319-0

Article  PubMed  Google Scholar 

Cho, Y.-H., et al. (2020). 5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation. Nature Communications. https://doi.org/10.1038/s41467-020-19173-2

Article  PubMed  PubMed Central  Google Scholar 

Del Rio, M., et al. (2007). Gene expression signature in advanced colorectal cancer patients select drugs and response for the use of leucovorin, fluorouracil, and irinotecan. Journal of Clinical Oncology. https://doi.org/10.1200/JCO.2006.07.4187

Article  PubMed  Google Scholar 

Xie, Y.-H., et al. (2020). Comprehensive review of targeted therapy for colorectal cancer. Signal Transduction and Targeted Therapy. https://doi.org/10.1038/s41392-020-0116-z

Article  PubMed  PubMed Central  Google Scholar 

Pramanik, A., et al. (2022). Affimer tagged cubosomes: Targeting of carcinoembryonic antigen expressing colorectal cancer cells using In Vitro and In Vivo models. ACS Applied Materials & Interfaces. https://doi.org/10.1021/acsami.1c21655

Article  Google Scholar 

Seymour, M. T., & Morton, D. (2019). FOxTROT: An international randomised controlled trial in 1052 patients (pts) evaluating neoadjuvant chemotherapy (NAC) for colon cancer. Journal of Clinical Oncology. https://doi.org/10.1200/JCO.2019.37.15_suppl.3504

Article  PubMed  PubMed Central  Google Scholar 

Correia, J. H., et al. (2021). Photodynamic therapy review: Principles, photosensitizers, applications, and future directions. Pharmaceutics. https://doi.org/10.3390/pharmaceutics13091332

Article  PubMed  PubMed Central  Google Scholar 

Allison, R. R., & Moghissi, K. (2013). Photodynamic therapy (PDT): PDT mechanisms. Clinical Endoscopy. https://doi.org/10.5946/ce.2013.46.1.24

Article  PubMed  PubMed Central  Google Scholar 

Robertson, C. A., et al. (2009). Photodynamic therapy (PDT): A short review on cellular mechanisms and cancer research applications for PDT. Journal of photochemistry and photobiology. B, Biology. https://doi.org/10.1016/j.jphotobiol.2009.04.001

Article  PubMed  Google Scholar 

Wachowska, M., et al. (2015). Immunological aspects of antitumor photodynamic therapy outcome. Central European Journal of Immunology. https://doi.org/10.5114/ceji.2015.56974

Article  PubMed  PubMed Central  Google Scholar 

Falk-Mahapatra, R., & Gollnick, S. O. (2020). Photodynamic therapy and immunity: An update. Photochemistry and Photobiology. https://doi.org/10.1111/php.13253

Article  PubMed  PubMed Central  Google Scholar 

Choudhary, N., et al. (2022). Hypericin and its anticancer effects: From mechanism of action to potential therapeutic application. Phytomedicine. https://doi.org/10.1016/j.phymed.2022.154356

Article  PubMed  Google Scholar 

Khot, M. I., et al. (2018). Inhibiting ABCG2 could potentially enhance the efficacy of hypericin-mediated photodynamic therapy in spheroidal cell models of colorectal cancer. Photodiagnosis and Photodynamic Therapy. https://doi.org/10.1016/j.pdpdt.2018.06.027

Article  PubMed  Google Scholar 

Kim, W. S., et al. (2022). AI-enabled, implantable, multichannel wireless telemetry for photodynamic therapy. Nature Communications. https://doi.org/10.1038/s41467-022-29878-1

Article  PubMed  PubMed Central  Google Scholar 

Khot, M. I., et al. (2020). The role of ABCG2 in modulating responses to anti-cancer photodynamic therapy. Photodiagnosis and Photodynamic Therapy. https://doi.org/10.1016/j.pdpdt.2019.10.014

Article  PubMed  Google Scholar 

Jendzelovsky, R., et al. (2009). Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells. Photochemical & Photobiological Sciences. https://doi.org/10.1039/b9pp00086k

Article  Google Scholar 

Khot, M. I., et al. (2020). Characterising a PDMS based 3D cell culturing microfluidic platform for screening chemotherapeutic drug cytotoxic activity. Scientific Reports. https://doi.org/10.1038/s41598-020-72952-1

Article  PubMed  PubMed Central  Google Scholar 

Breslin, S., & O’Driscoll, L. (2013). Three-dimensional cell culture: The missing link in drug discovery. Drug Discovery Today. https://doi.org/10.1016/j.drudis.2012.10.003

Article  PubMed  Google Scholar 

Zanoni, M., et al. (2016). 3D tumor spheroid models for in vitro therapeutic screening: A systematic approach to enhance the biological relevance of data obtained. Scientific Reports. https://doi.org/10.1038/srep19103

Article  PubMed  PubMed Central  Google Scholar 

Toyoda, Y., et al. (2019). Inhibitors of Human ABCG2: From technical background to recent updates with clinical implications. Frontiers in Pharmacology. https://doi.org/10.3389/fphar.2019.00208

Article  PubMed  PubMed Central  Google Scholar 

Miyata, H., et al. (2016). Identification of febuxostat as a new strong ABCG2 inhibitor: Potential applications and risks in clinical situations. Frontiers in Pharmacology. https://doi.org/10.3389/fphar.2016.00518

Article  PubMed  PubMed Central  Google Scholar 

Cramer, S. W., & Chen, C. C. (2020). Photodynamic therapy for the treatment of glioblastoma. Frontiers in Surgery. https://doi.org/10.3389/fsurg.2019.00081

Article  PubMed  PubMed Central  Google Scholar 

Kast, R. E., et al. (2018). Augmentation of 5-aminolevulinic acid treatment of glioblastoma by adding ciprofloxacin, deferiprone, 5-fluorouracil and febuxostat: The CAALA regimen. Brain Sciences. https://doi.org/10.3390/brainsci8120203

Article  PubMed  PubMed Central  Google Scholar 

Zattoni, I. F., et al. (2022). Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators. European Journal of Medicinal Chemistry. https://doi.org/10.1016/j.ejmech.2022.114346

Article  PubMed  Google Scholar 

Abdel-Aziz, A. M., et al. (2020). Amelioration of testosterone-induced benign prostatic hyperplasia using febuxostat in rats: The role of VEGF/TGFβ and iNOS/COX-2. European Journal of Pharmacology. https://doi.org/10.1016/j.ejphar.2020.173631

Article  PubMed  Google Scholar 

Englund, G., et al. (2007). Efflux transporters in ulcerative colitis: Decreased expression of BCRP (ABCG2) and Pgp (ABCB1). Inflammatory Bowel Diseases. https://doi.org/10.1002/ibd.20030

Article  PubMed  Google Scholar 

Gutmann, H., et al. (2008). Breast cancer resistance protein and P-glycoprotein expression in patients with newly diagnosed and therapy-refractory ulcerative colitis compared with healthy controls. Digestion. https://doi.org/10.1159/000179361

Article  PubMed  Google Scholar 

Kukal, S., et al. (2021). Multidrug efflux transporter ABCG2: Expression and regulation. Cellular and Molecular Life Sciences. https://doi.org/10.1007/s00018-021-03901-y

Article  PubMed  Google Scholar 

Tan, L., et al. (2022). The role of photodynamic therapy in triggering cell death and facilitating antitumor immunology. Frontiers in Oncology. https://doi.org/10.3389/fonc.2022.863107

Article  PubMed  PubMed Central  Google Scholar 

Nakanishi, T., & Ross, D. D. (2012). Breast cancer resistance protein (BCRP/ABCG2): Its role in multidrug resistance and regulation of its gene expression. Chinese Journal of Cancer. https://doi.org/10.5732/cjc.011.10320

Article  PubMed  PubMed Central  Google Scholar 

Doyle, L. A., et al. (1998). A multidrug resistance transporter from human MCF-7 breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.95.26.15665

Article  PubMed  PubMed Central  Google Scholar 

Miyake, K., et al. (1999). Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: Demonstration of homology to ABC transport genes. Cancer Research, 59(1), 8–13.

CAS  PubMed  Google Scholar 

Maliepaard, M., et al. (1999). Overexpression of the BCRP/MXR/ABCP gene in a topotecan-selected ovarian tumor cell line. Cancer Research, 59(18), 4559–4563.

CAS  PubMed  Google Scholar 

Robey, R. W., et al. (2001). Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research, 7(1), 145–152.

CAS  PubMed  Google Scholar 

Burger, H., et al. (2005). Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps. Cancer Biology & Therapy. https://doi.org/10.4161/cbt.4.7.1826

Article  Google Scholar 

Mirrakhimov, A. E., et al. (2015). Tumor lysis syndrome: A clinical review. World Journal of Critical Care Medicine. https://doi.org/10.5492/wjccm.v4.i2.130

Article  PubMed  PubMed Central