Rationale and Design of the IMPROVE Trial: A Multicenter, Randomized, Controlled, Open-label, Blinded-endpoint Trial Assessing the Efficacy of Remote Ischemic Conditioning in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting

Doenst T, Haverich A, Serruys P, et al. PCI and CABG for treating stable coronary artery disease: JACC review topic of the week. J Am Coll Cardiol. 2019;73(8):964–76. https://doi.org/10.1016/j.jacc.2018.11.053.

Article  PubMed  Google Scholar 

Besch G, Perrotti A, Salomon du Mont L, et al. Impact of intravenous exenatide infusion for perioperative blood glucose control on myocardial ischemia-reperfusion injuries after coronary artery bypass graft surgery: sub study of the phase II/III ExSTRESS randomized trial. Cardiovasc Diabetol. 2018;17(1):140. https://doi.org/10.1186/s12933-018-0784-y.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kamenshchikov NO, Mandel IA, Podoksenov YK, et al. Nitric oxide provides myocardial protection when added to the cardiopulmonary bypass circuit during cardiac surgery: randomized trial. J Thorac Cardiovasc Surg. 2019;157(6):2328-36.e1. https://doi.org/10.1016/j.jtcvs.2018.08.117.

Article  CAS  PubMed  Google Scholar 

Lemoine S, Zhu L, Gérard JL, Hanouz JL. Sevoflurane-induced cardioprotection in coronary artery bypass graft surgery: randomised trial with clinical and ex-vivo endpoints. Anaesth Crit Care Pain Med. 2018;37(3):217–23. https://doi.org/10.1016/j.accpm.2017.05.009.

Article  PubMed  Google Scholar 

Wang J, Toan S, Zhou H. New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury. Angiogenesis. 2020;23(3):299–314. https://doi.org/10.1007/s10456-020-09720-2.

Article  CAS  PubMed  Google Scholar 

de Waard D, Fagan A, Minnaar C, Horne D. Management of patients after coronary artery bypass grafting surgery: a guide for primary care practitioners. CMAJ. 2021;193(19):E689–94. https://doi.org/10.1503/cmaj.191108.

Article  PubMed  PubMed Central  Google Scholar 

Shaefi S, Mittel A, Loberman D, Ramakrishna H. Off-pump versus on-pump coronary artery bypass grafting-a systematic review and analysis of clinical outcomes. J Cardiothorac Vasc Anesth. 2019;33(1):232–44. https://doi.org/10.1053/j.jvca.2018.04.012.

Article  PubMed  Google Scholar 

Ofoegbu CKP, Manganyi RM. Off-pump coronary artery bypass grafting; is it still relevant? Curr Cardiol Rev. 2022;18(2): e271021197431. https://doi.org/10.2174/1573403x17666211027141043.

Article  PubMed  PubMed Central  Google Scholar 

Benedetto U, Altman DG, Gerry S, et al. Off-pump versus on-pump coronary artery bypass grafting: insights from the arterial revascularization trial. J Thorac Cardiovasc Surg. 2018;155(4):1545-53.e7. https://doi.org/10.1016/j.jtcvs.2017.10.135.

Article  PubMed  Google Scholar 

Cour M, Lecour S. Remote ischaemic conditioning: in search of a suitable match. Nat Rev Cardiol. 2019;16(12):704–5. https://doi.org/10.1038/s41569-019-0296-9.

Article  PubMed  Google Scholar 

Kharbanda RK, Mortensen UM, White PA, et al. Transient limb ischemia induces remote ischemic preconditioning in vivo. Circulation. 2002;106(23):2881–3. https://doi.org/10.1161/01.cir.0000043806.51912.9b.

Article  CAS  PubMed  Google Scholar 

Pickard JM, Davidson SM, Hausenloy DJ, Yellon DM. Co-dependence of the neural and humoral pathways in the mechanism of remote ischemic conditioning. Basic Res Cardiol. 2016;111(4):50. https://doi.org/10.1007/s00395-016-0568-z.

Article  PubMed  PubMed Central  Google Scholar 

Aimo A, Borrelli C, Giannoni A, et al. Cardioprotection by remote ischemic conditioning: mechanisms and clinical evidences. World J Cardiol. 2015;7(10):621–32. https://doi.org/10.4330/wjc.v7.i10.621.

Article  PubMed  PubMed Central  Google Scholar 

Kloner RA, Shi J, Dai W, Carreno J, Zhao L. Remote ischemic conditioning in acute myocardial infarction and shock states. J Cardiovasc Pharmacol Ther. 2020;25(2):103–9. https://doi.org/10.1177/1074248419892603.

Article  PubMed  Google Scholar 

Saccaro LF, Aimo A, Emdin M, Pico F. Remote ischemic conditioning in ischemic stroke and myocardial infarction: similarities and differences. Front Neurol. 2021;12:716316. https://doi.org/10.3389/fneur.2021.716316.

Article  PubMed  PubMed Central  Google Scholar 

Gill R, Kuriakose R, Gertz ZM, Salloum FN, Xi L, Kukreja RC. Remote ischemic preconditioning for myocardial protection: update on mechanisms and clinical relevance. Mol Cell Biochem. 2015;402(1–2):41–9. https://doi.org/10.1007/s11010-014-2312-z.

Article  CAS  PubMed  Google Scholar 

Bell RM, Basalay M, Bøtker HE, et al. Remote ischaemic conditioning: defining critical criteria for success-report from the 11th Hatter Cardiovascular Workshop. Basic Res Cardiol. 2022;117(1):39. https://doi.org/10.1007/s00395-022-00947-2.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ho AFW, Chong J, Ong MEH, Hausenloy DJ. Remote ischemic conditioning in emergency medicine-clinical frontiers and research opportunities. Shock. 2020;53(3):269–76. https://doi.org/10.1097/shk.0000000000001362.

Article  PubMed  Google Scholar 

Moscarelli M, Fiorentino F, Suleiman MS, et al. Remote ischaemic preconditioning in isolated aortic valve and coronary artery bypass surgery: a randomized trial. Eur J Cardiothorac Surg. 2019;55(5):905–12. https://doi.org/10.1093/ejcts/ezy404.

Article  PubMed  Google Scholar 

Ney J, Hoffmann K, Meybohm P, et al. Remote ischemic preconditioning does not affect the release of humoral factors in propofol-anesthetized cardiac surgery patients: a secondary analysis of the RIPHeart study. Int J Mol Sci. 2018. https://doi.org/10.3390/ijms19041094.

Article  PubMed  PubMed Central  Google Scholar 

Meybohm P, Bein B, Brosteanu O, et al. A multicenter trial of remote ischemic preconditioning for heart surgery. N Engl J Med. 2015;373(15):1397–407. https://doi.org/10.1056/NEJMoa1413579.

Article  CAS  PubMed  Google Scholar 

Møller CH, Perko MJ, Lund JT, et al. No major differences in 30-day outcomes in high-risk patients randomized to off-pump versus on-pump coronary bypass surgery: the best bypass surgery trial. Circulation. 2010;121(4):498–504. https://doi.org/10.1161/circulationaha.109.880443.

Article  PubMed  Google Scholar 

Johnsen J, Pryds K, Salman R, Løfgren B, Kristiansen SB, Bøtker HE. The remote ischemic preconditioning algorithm: effect of number of cycles, cycle duration and effector organ mass on efficacy of protection. Basic Res Cardiol. 2016;111(2):10. https://doi.org/10.1007/s00395-016-0529-6.

Article  PubMed  Google Scholar 

Chen HS, Cui Y, Li XQ, et al. Effect of remote ischemic conditioning vs usual care on neurologic function in patients with acute moderate ischemic stroke: the RICAMIS randomized clinical trial. JAMA. 2022;328(7):627–36. https://doi.org/10.1001/jama.2022.13123.

Article  PubMed  PubMed Central  Google Scholar 

Hausenloy DJ, Candilio L, Evans R, et al. Remote ischemic preconditioning and outcomes of cardiac surgery. N Engl J Med. 2015;373(15):1408–17. https://doi.org/10.1056/NEJMoa1413534.

Article  CAS  PubMed  Google Scholar 

Meng R, Asmaro K, Meng L, et al. Upper limb ischemic preconditioning prevents recurrent stroke in intracranial arterial stenosis. Neurology. 2012;79(18):1853–61. https://doi.org/10.1212/WNL.0b013e318271f76a.

Article  PubMed  Google Scholar 

Mastitskaya S, Basalay M, Hosford PS, Ramage AG, Gourine A, Gourine AV. Identifying the source of a humoral factor of remote (pre)conditioning cardioprotection. PLoS ONE. 2016;11(2):e0150108. https://doi.org/10.1371/journal.pone.0150108.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cho YJ, Nam K, Kim TK, et al. Sevoflurane, propofol and carvedilol block myocardial protection by limb remote ischemic preconditioning. Int J Mol Sci. 2019. https://doi.org/10.3390/ijms20020269.

Article  PubMed  PubMed Central  Google Scholar 

Tyagi S, Singh N, Virdi JK, Jaggi AS. Diabetes abolish cardioprotective effects of remote ischemic conditioning: evidences and possible mechanisms. J Physiol Biochem. 2019;75(1):19–28. https://doi.org/10.1007/s13105-019-00664-w.

Article  CAS  PubMed  Google Scholar 

Chen Z, Wang D, Ma M, et al. Rationale and design of the OPTIMAL-REPERFUSION trial: a prospective randomized multi-center clinical trial comparing different fibrinolysis-transfer percutaneous coronary intervention strategies in acute ST-segment elevation myocardial infarction. Clin Cardiol. 2021;44(4):455–62. https://doi.org/10.1002/clc.23582.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pölzl L, Thielmann M, Cymorek S, et al. Impact of myocardial injury after coronary artery bypass grafting on long-term prognosis. Eur Heart J. 2022;43(25):2407–17. https://doi.org/10.1093/eurheartj/ehac054.

Article  PubMed  Google Scholar 

留言 (0)

沒有登入
gif