Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2

Non-covalent PLpro inhibitors

Antiviral activity

Structural-based drug design

Imidazo[4,5-b]pyridine scaffold

© 2024 Published by Elsevier B.V. on behalf of Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences.

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