Novovic K, Jovcic B (2023) Colistin Resistance in Acinetobacter baumannii: Molecular mechanisms and Epidemiology. Antibiot (Basel) 12(3). https://doi.org/10.3390/antibiotics12030516

Zhang J, Xie J, Li H, Wang Z, Yin Y, Wang S, Chen H, Wang Q, Wang H (2022) Genomic and phenotypic evolution of Tigecycline-Resistant Acinetobacter baumannii in critically ill patients. Microbiol Spectr 10(1):e0159321. https://doi.org/10.1128/spectrum.01593-21

Article  PubMed  Google Scholar 

Visca P, Seifert H, Towner KJ (2011) Acinetobacter infection–an emerging threat to human health. IUBMB Life 63(12):1048–1054. https://doi.org/10.1002/iub.534

Article  CAS  PubMed  Google Scholar 

Paterson DL, Harris PN (2015) Editorial commentary: the new Acinetobacter equation: hypervirulence plus antibiotic resistance equals big trouble. Clin Infect Dis 61(2):155–156. https://doi.org/10.1093/cid/civ227

Article  PubMed  Google Scholar 

Yaghoubi S, Zekiy AO, Krutova M, Gholami M, Kouhsari E, Sholeh M, Ghafouri Z, Maleki F (2022) Tigecycline antibacterial activity, clinical effectiveness, and mechanisms and epidemiology of resistance: narrative review. Eur J Clin Microbiol Infect Dis 41(7):1003–1022. https://doi.org/10.1007/s10096-020-04121-1

Article  CAS  PubMed  Google Scholar 

Deng M, Zhu MH, Li JJ, Bi S, Sheng ZK, Hu FS, Zhang JJ, Chen W, Xue XW, Sheng JF, Li LJ (2014) Molecular epidemiology and mechanisms of tigecycline resistance in clinical isolates of Acinetobacter baumannii from a Chinese university hospital. Antimicrob Agents Chemother 58(1):297–303. https://doi.org/10.1128/AAC.01727-13

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nigro SJ, Hall RM (2012) Antibiotic resistance islands in A320 (RUH134), the reference strain for Acinetobacter baumannii global clone 2. J Antimicrob Chemother 67(2):335–338. https://doi.org/10.1093/jac/dkr447

Article  CAS  PubMed  Google Scholar 

Viehman JA, Nguyen MH, Doi Y (2014) Treatment options for carbapenem-resistant and extensively drug-resistant Acinetobacter baumannii infections. Drugs 74(12):1315–1333. https://doi.org/10.1007/s40265-014-0267-8

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun JR, Chan MC, Chang TY, Wang WY, Chiueh TS (2010) Overexpression of the adeB gene in clinical isolates of tigecycline-nonsusceptible Acinetobacter baumannii without insertion mutations in adeRS. Antimicrob Agents Chemother 54(11):4934–4938. https://doi.org/10.1128/AAC.00414-10

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang YS, Chen HY, Hsu WJ, Chou YC, Perng CL, Shang HS, Hsiao YT, Sun JR, group As (2019) Overexpression of AdeABC efflux pump associated with tigecycline resistance in clinical Acinetobacter nosocomialis isolates. Clin Microbiol Infect 25 (4):512 e511-512 e516 https://doi.org/10.1016/j.cmi.2018.06.012

Coyne S, Rosenfeld N, Lambert T, Courvalin P, Perichon B (2010) Overexpression of resistance-nodulation-cell division pump AdeFGH confers multidrug resistance in Acinetobacter baumannii. Antimicrob Agents Chemother 54(10):4389–4393. https://doi.org/10.1128/AAC.00155-10

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jo J, Ko KS (2021) Tigecycline Heteroresistance and Resistance mechanism in clinical isolates of Acinetobacter baumannii. Microbiol Spectr 9(2):e0101021. https://doi.org/10.1128/Spectrum.01010-21

Article  PubMed  Google Scholar 

Hua X, He J, Wang J, Zhang L, Zhang L, Xu Q, Shi K, Leptihn S, Shi Y, Fu X, Zhu P, Higgins PG, Yu Y (2021) Novel tigecycline resistance mechanisms in Acinetobacter baumannii mediated by mutations in adeS, rpoB and Rrf. Emerg Microbes Infect 10(1):1404–1417. https://doi.org/10.1080/22221751.2021.1948804

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen Q, Li X, Zhou H, Jiang Y, Chen Y, Hua X, Yu Y (2014) Decreased susceptibility to tigecycline in Acinetobacter baumannii mediated by a mutation in trm encoding SAM-dependent methyltransferase. J Antimicrob Chemother 69(1):72–76. https://doi.org/10.1093/jac/dkt319

Article  CAS  PubMed  Google Scholar 

He T, Wang R, Liu D, Walsh TR, Zhang R, Lv Y, Ke Y, Ji Q, Wei R, Liu Z, Shen Y, Wang G, Sun L, Lei L, Lv Z, Li Y, Pang M, Wang L, Sun Q, Fu Y, Song H, Hao Y, Shen Z, Wang S, Chen G, Wu C, Shen J, Wang Y (2019) Emergence of plasmid-mediated high-level tigecycline resistance genes in animals and humans. Nat Microbiol 4(9):1450–1456. https://doi.org/10.1038/s41564-019-0445-2

Article  CAS  PubMed  Google Scholar 

Zheng XR, Zhu JH, Zhang J, Cai P, Sun YH, Chang MX, Fang LX, Sun J, Jiang HX (2020) A novel plasmid-borne tet(X6) variant co-existing with blaNDM-1 and blaOXA-58 in a chicken Acinetobacter baumannii isolate. J Antimicrob Chemother 75(11):3397–3399. https://doi.org/10.1093/jac/dkaa342

Article  CAS  PubMed  Google Scholar 

Hsieh YC, Wu JW, Chen YY, Quyen TLT, Liao WC, Li SW, Chen YC, Pan YJ (2021) An outbreak of tet(X6)-Carrying tigecycline-resistant Acinetobacter baumannii isolates with a New Capsular type at a hospital in Taiwan. Antibiot (Basel) 1010. https://doi.org/10.3390/antibiotics10101239

Jiang M, Chen X, Liu S, Zhang Z, Li N, Dong C, Zhang L, Wu H, Zhao S (2021) Epidemiological analysis of Multidrug-Resistant Acinetobacter baumannii isolates in a Tertiary Hospital over a 12-Year period in China. Front Public Health 9:707435. https://doi.org/10.3389/fpubh.2021.707435

Article  PubMed  PubMed Central  Google Scholar 

Jiang L, Liang Y, Yao W, Ai J, Wang X, Zhao Z (2019) Molecular epidemiology and genetic characterisation of carbapenem-resistant Acinetobacter baumannii isolates from Guangdong Province, South China. J Glob Antimicrob Resist 17:84–89. https://doi.org/10.1016/j.jgar.2018.11.002

Article  PubMed  Google Scholar 

Qu J, Du Y, Yu R, Lu X (2016) The First Outbreak Caused by Acinetobacter baumannii ST208 and ST195 in China. Biomed Res Int 2016:9254907 https://doi.org/10.1155/2016/9254907

Ying J, Lu J, Zong L, Li A, Pan R, Cheng C, Li K, Chen L, Ying J, Tou H, Zhu C, Xu T, Yi H, Li J, Ni L, Xu Z, Bao Q, Li P (2016) Molecular epidemiology and characterization of genotypes of Acinetobacter baumannii isolates from regions of South China. Jpn J Infect Dis 69(3):180–185. https://doi.org/10.7883/yoken.JJID.2014.544

Article  CAS  PubMed  Google Scholar