Lymphocyte antigen 96: A new potential biomarker and immune target in Parkinson's disease

ΔΨm

mitochondrial transmembrane potential

CD44

cluster of differentiation 44

CCR2

C-C chemokine receptor type 2

DMEM

Dulbecco's Modified Eagle Medium

GAPDH

glyceraldehyde phosphate dehydrogenase

GEO

Gene Expression Omnibus

GSEA

gene set enrichment analysis

GSVA

gene set variation analysis

HMGB

high mobility group box

IC50

half inhibitory concentration

KEGG

Kyoto Encyclopedia of Genes and Genomes

LBP

lipopolysaccharide binding protein

LY96

Lymphocyte antigen 96

MD2

myeloid differentiation 2

MDSCs

myeloid-derived suppressor cells

MMP

mitochondrial membrane potential

MPP+

N-methyl-4-phenylpyridinium iodide

MPTP

1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine

PBS

phosphate-buffered saline

PPI

protein-protein interaction

ROC

receiver operating characteristic

RT-qPCR

reverse transcription-quantitative polymerase chain reaction

siRNA

small interfering RNA

ssGSEA

single-sample gene set enrichment analysis

TIRAP

TIR domain containing adaptor protein

UPDRS

Unified Parkinson's Disease Rating Scale

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