Underwood MA, Gilbert WM, Sherman MP. Amniotic fluid: not just fetal urine anymore. J Perinatol. 2005;25(5):341–8.

Article  PubMed  Google Scholar 

Wintour EM, Shandley L. Effects of fetal fluid balance on amniotic fluid volume. Semin Perinatol. 1993;17(3):158–72.

CAS  PubMed  Google Scholar 

Moore TR. Amniotic fluid dynamics reflect fetal and maternal health and disease. Obstet Gynecol. 2010;116(3):759–65.

Article  PubMed  Google Scholar 

Sherer DM. A review of amniotic fluid dynamics and the enigma of isolated oligohydramnios. Am J Perinatol. 2002;19(5):253–66.

Article  PubMed  Google Scholar 

Beall MH, van den Wijngaard JP, van Gemert MJ, Ross MG. Amniotic fluid water dynamics. Placenta. 2007;28(8–9):816–23.

Article  CAS  PubMed  Google Scholar 

Shamsnajafabadi H, Soheili ZS. Amniotic fluid characteristics and its application in stem cell therapy: a review. Int J Reprod Biomed. 2022;20(8):627–43.

CAS  PubMed  PubMed Central  Google Scholar 

Ross MG, Nijland MJM. Development of ingestive behavior. Am J Physiol Regul Integr Comp Physiol. 1998;274(4):R879–93.

Article  CAS  Google Scholar 

Rabinowitz R, Peters MT, Vyas S, Campbell S, Nicolaides KH. Measurement of fetal urine production in normal pregnancy by real-time ultrasonography. Am J Obstet Gynecol. 1989;161(5):1264–6.

Article  CAS  PubMed  Google Scholar 

Pierce J, Jacobson P, Benedetti E, Peterson E, Phibbs J, Preslar A, et al. Collection and characterization of amniotic fluid from scheduled C-section deliveries. Cell Tissue Bank. 2016;17(3):413–25.

Article  CAS  PubMed  Google Scholar 

Tong XL, Wang L, Gao TB, Qin YG, Qi YQ, Xu YP. Potential function of amniotic fluid in fetal development–-novel insights by comparing the composition of human amniotic fluid with umbilical cord and maternal serum at mid and late gestation. J Chin Med Assoc. 2009;72(7):368–73.

Article  CAS  PubMed  Google Scholar 

Mao Y, Pierce J, Singh-Varma A, Boyer M, Kohn J, Reems J-A. Processed human amniotic fluid retains its antibacterial activity. J Transl Med. 2019;17(1):68.

Article  PubMed  PubMed Central  Google Scholar 

Colombo M, Raposo G, Théry C. Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu Rev Cell Dev Biol. 2014;30(1):255–89.

Article  CAS  PubMed  Google Scholar 

Meehan B, Rak J, Di Vizio D. Oncosomes—large and small: what are they, where they came from? J Extracell Vesicles. 2016;5:33109.

Article  PubMed  Google Scholar 

Pan BT, Teng K, Wu C, Adam M, Johnstone RM. Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes. J Cell Biol. 1985;101(3):942–8.

Article  CAS  PubMed  Google Scholar 

Harding C, Heuser J, Stahl P. Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes. J Cell Biol. 1983;97(2):329–39.

Article  CAS  PubMed  Google Scholar 

Kang T, Atukorala I, Mathivanan S. Biogenesis of extracellular vesicles. In: Mathivanan S, Fonseka P, Nedeva C, Atukorala I, editors. New frontiers: extracellular vesicles. Cham: Springer International Publishing; 2021. p. 19–43.

Chapter  Google Scholar 

Abels ER, Breakefield XO. Introduction to extracellular vesicles: biogenesis, RNA cargo selection, content, release, and uptake. Cell Mol Neurobiol. 2016;36(3):301–12.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Witwer KW, Buzás EI, Bemis LT, Bora A, Lässer C, Lötvall J, et al. Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J Extracell Vesicles. 2013;2(1):20360.

Article  Google Scholar 

Barry OP, Praticò D, Savani RC, FitzGerald GA. Modulation of monocyte-endothelial cell interactions by platelet microparticles. J Clin Invest. 1998;102(1):136–44.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cossetti C, Iraci N, Mercer TR, Leonardi T, Alpi E, Drago D, et al. Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells. Mol Cell. 2014;56(2):193–204.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kalluri R. The biology and function of exosomes in cancer. J Clin Investig. 2016;126(4):1208–15.

Article  PubMed  PubMed Central  Google Scholar 

Keller S, Ridinger J, Rupp A-K, Janssen JWG, Altevogt P. Body fluid derived exosomes as a novel template for clinical diagnostics. J Transl Med. 2011;9(1):86.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sterzenbach U, Putz U, Low LH, Silke J, Tan SS, Howitt J. Engineered exosomes as vehicles for biologically active proteins. Mol Ther. 2017;25(6):1269–78.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Du R, Wang C, Zhu L, Yang Y. Extracellular vesicles as delivery vehicles for therapeutic nucleic acids in cancer gene therapy: progress and challenges. Pharmaceutics. 2022;14(10):2236.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Al-Dossary AA, Strehler EE, Martin-Deleon PA. Expression and secretion of plasma membrane Ca2+-ATPase 4a (PMCA4a) during murine estrus: association with oviductal exosomes and uptake in sperm. PLoS ONE. 2013;8(11): e80181.

Article  PubMed  PubMed Central  Google Scholar 

Burns G, Brooks K, Wildung M, Navakanitworakul R, Christenson LK, Spencer TE. Extracellular vesicles in luminal fluid of the ovine uterus. PLoS ONE. 2014;9(3): e90913.

Article  PubMed  PubMed Central  Google Scholar 

O’Neil EV, Burns GW, Spencer TE. Extracellular vesicles: novel regulators of conceptus-uterine interactions? Theriogenology. 2020;150:106–12.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nakamura K, Kusama K, Suda Y, Fujiwara H, Hori M, Imakawa K. Emerging role of extracellular vesicles in embryo-maternal communication throughout implantation processes. Int J Mol Sci. 2020;21(15):5523.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Salomon C, Yee SW, Mitchell MD, Rice GE. The possible role of extravillous trophoblast-derived exosomes on the uterine spiral arterial remodeling under both normal and pathological conditions. Biomed Res Int. 2014;2014: 693157.

Article  PubMed  PubMed Central  Google Scholar 

Dixon CL, Sheller-Miller S, Saade GR, Fortunato SJ, Lai A, Palma C, et al. Amniotic fluid exosome proteomic profile exhibits unique pathways of term and preterm labor. Endocrinology. 2018;159(5):2229–40.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wan S, Chen P, Gu M, Liu J, Zhou Q, Zhang F, et al. Fetal lung-derived exosomes in term labor amniotic fluid induce amniotic membrane senescence. Front Cell Dev Biol. 2022;10: 889861.

Article  PubMed  PubMed Central  Google Scholar 

Gebara N, Scheel J, Skovronova R, Grange C, Marozio L, Gupta S, et al. Single extracellular vesicle analysis in human amniotic fluid shows evidence of phenotype alterations in preeclampsia. J Extracell Vesicles. 2022;11(5): e12217.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhatti G, Romero R, Rice GE, Fitzgerald W, Pacora P, Gomez-Lopez N, et al. Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor. PLoS ONE. 2020;15(1): e0227881.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xie J, Zhou Y, Gao W, Li Z, Xu Z, Zhou L. The relationship between amniotic fluid miRNAs and congenital obstructive nephropathy. Am J Transl Res. 2017;9(4):1754–63.

CAS  PubMed  PubMed Central  Google Scholar 

Tavanasefat H, Li F, Koyano K, Gourtani BK, Marty V, Mulpuri Y, et al. Molecular consequences of fetal alcohol exposure on amniotic exosomal miRNAs with functional implications for stem cell potency and differentiation. PLoS ONE. 2020;15(11): e0242276.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Haney MJ, Klyachko NL, Zhao Y, Gupta R, Plotnikova EG, He Z, et al. Exosomes as drug delivery vehicles for Parkinson’s disease therapy. J Control Release. 2015;207:18–30.

Article  CAS  PubMed  PubMed Central