Wilcox I, McNamara SG, Collins FL, Grunstein RR, Sullivan CE. “Syndrome Z”: the interaction of sleep apnoea, vascular risk factors and heart disease. Thorax. 1998;53:S25–28.

PubMed  PubMed Central  Google Scholar 

Chaudhary P, Goyal A, Goel SK, Kumar A, Chaudhary S, Kirti Keshri S, et al. Women with OSA have higher chances of having metabolic syndrome than men: effect of gender on syndrome Z in cross sectional study. Sleep Med. 2021;79:83–7.

Article  PubMed  Google Scholar 

Kaplan NM. The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension. Arch Intern Med. 1989;149:1514–20.

Article  CAS  PubMed  Google Scholar 

Kapur VK, Auckley DH, Chowdhuri S, Kuhlmann DC, Mehra R, Ramar K, et al. Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2017;13:479–504.

Article  PubMed  PubMed Central  Google Scholar 

Koo CY, de la Torre AS, Loo G, Torre MS, Zhang J, Duran-Cantolla J, et al. Effects of ethnicity on the prevalence of obstructive sleep apnoea in patients with acute coronary syndrome: a pooled analysis of the ISAACC trial and sleep and stent study. Heart Lung Circ. 2017;26:486–94.

Article  PubMed  Google Scholar 

Hamer M, Stamatakis E. Metabolically healthy obesity and risk of all-cause and cardiovascular disease mortality. J Clin Endocrinol Metab. 2012;97:2482–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kim SA, Lim K, Lee JK, Kang D, Shin S. Metabolically healthy obesity and the risk of all-cause and cardiovascular disease mortality in a Korean population: a prospective cohort study. BMJ Open. 2021;11:e049063.

Article  PubMed  Google Scholar 

Inoue M, Sakata S, Arima H, Yamato I, Oishi E, Ibaraki A. Sleep-related breathing disorder in a Japanese occupational population and its association with hypertension—stratified analysis by obesity status. Hypertens Res. 2024. https://doi.org/10.1038/s41440-024-01612-y.

Article  PubMed  Google Scholar 

Hoshide S, Kario K, Chia YC, Siddique S, Buranakitjaroen P, Tsoi K, et al. Characteristics of hypertension in obstructive sleep apnea: an Asian experience. J Clin Hypertens. 2021;23:489–95.

Article  Google Scholar 

Chaudhary P, Goyal A, Pakhare A, Goel SK, Kumar A, Reddy MA, et al. Metabolic syndrome in non-obese patients with OSA: learning points of a cross-sectional study from a tertiary care hospital in Central India. Sleep Breath. 2022;26:681–8.

Article  PubMed  Google Scholar 

Grassi G, Seravalle G, Brambilla G, Buzzi S, Volpe M, Cesana F, et al. Regional differences in sympathetic activation in lean and obese normotensive individuals with obstructive sleep apnoea. J Hypertens. 2014;32:383–8.

Article  CAS  PubMed  Google Scholar 

Pamidi S, Wroblewski K, Broussard J, Day A, Hanlon EC, Abraham V, et al. Obstructive sleep apnea in young lean men: impact on insulin sensitivity and secretion. Diabetes Care. 2012;35:2384–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Miyamura M, Schnell O, Yamashita C, Yoshioka T, Matsumoto C, Mori T, et al. Effects of acarbose on the acceleration of postprandial hyperglycemia-induced pathological changes induced by intermittent hypoxia in lean mice. J Pharm Sci. 2010;114:32–40.

Article  CAS  Google Scholar 

Almendros I, Basoglu ÖK, Conde SV, Liguori C, Saaresranta T. Metabolic dysfunction in OSA: is there something new under the sun? J Sleep Res. 2022;31:e13418.

Article  PubMed  Google Scholar 

Coughlin SR, Mawdsley L, Mugarza JA, Wilding JP, Calverley PM. Cardiovascular and metabolic effects of CPAP in obese males with OSA. Eur Respir J. 2007;29:720–7.

Article  CAS  PubMed  Google Scholar 

Arias MA, García-Río F, Alonso-Fernández A, Mediano O, Martínez I, Villamor J. Obstructive sleep apnea syndrome affects left ventricular diastolic function: effects of nasal continuous positive airway pressure in men. Circulation. 2005;112:375–83.

Article  PubMed  Google Scholar 

Feng J, Li K, Luo W, Xie F, Li M, Wu Y. Effect of continuous positive pressure ventilation on left ventricular diastolic function E/A ratio in patients with obstructive sleep apnea: a meta-analysis. Sleep Breath. 2023;27:2333–40.

Article  PubMed  Google Scholar 

Altintas N, Riha RL. Non-sleepy obstructive sleep apnoea: to treat or not to treat? Eur Respir Rev. 2019;28:190031.

Article  PubMed  PubMed Central  Google Scholar 

Reaven GM. Role of insulin resistance in human disease (syndrome X): an expanded definition. Annu Rev Med. 1993;44:121–31.

Article  CAS  PubMed  Google Scholar