Peerapornratana S, Manrique-Caballero CL, Gómez H, Kellum JA. Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment. Kidney Int. 2019;96(5):1083–99.
Article PubMed PubMed Central Google Scholar
Gumbert SD, Kork F, Jackson ML, Vanga N, Ghebremichael SJ, Wang CY, et al. Perioperative acute kidney injury. Anesthesiology. 2020;132(1):180–204.
Medić B, Stojanović M, Rovčanin B, Kekić D, Škodrić SR, Jovanović GB, et al. Pioglitazone attenuates kidney injury in an experimental model of gentamicin-induced nephrotoxicity in rats. Sci Rep. 2019;9(7):13689.
Article PubMed PubMed Central Google Scholar
Jha JC, Banal C, Chow BS, Cooper ME, Jandeleit-Dahm K. Diabetes and kidney disease: role of oxidative stress. Antioxid Redox Signal. 2016;25(12):657–84.
Article CAS PubMed PubMed Central Google Scholar
Zou G, Zhou Z, Xi X, Huang R, Hu H. Pioglitazone ameliorates renal ischemia-reperfusion injury via inhibition of NF-κB activation and inflammation in rats. Front Physiol. 2021;12: 707344.
Article PubMed PubMed Central Google Scholar
Kaltenmeier C, Wang R, Popp B, Geller D, Tohme S, Yazdani HO. Role of immuno-inflammatory signals in liver ischemia-reperfusion injury. Cells. 2022;11(14):2222.
Article CAS PubMed PubMed Central Google Scholar
Pefanis A, Ierino FL, Murphy JM, Cowan PJ. Regulated necrosis in kidney ischemia-reperfusion injury. Kidney Int. 2019;96(2):291–301.
Su L, Zhang J, Gomez H, Kellum JA, Peng Z. Mitochondria ROS and mitophagy in acute kidney injury. Autophagy. 2023;19(2):401–14.
Article CAS PubMed Google Scholar
Zhang BH, Liu H, Yuan Y, Weng XD, Du Y, Chen H, et al. Knockdown of TRIM8 protects HK-2 cells against hypoxia/reoxygenation-induced injury by inhibiting oxidative stress-mediated apoptosis and pyroptosis via PI3K/Akt signal pathway. Drug Des Dev Ther. 2021;15:4973–83.
Liu W, Gan Y, Ding Y, Zhang L, Jiao X, Liu L, et al. Autophagy promotes GSDME-mediated pyroptosis via intrinsic and extrinsic apoptotic pathways in cobalt chloride-induced hypoxia reoxygenation-acute kidney injury. Ecotoxicol Environ Saf. 2022;242:113881.
Article CAS PubMed Google Scholar
Devchand PR, Liu T, Altman RB, FitzGerald GA, Schadt EE. The pioglitazone trek via human PPAR gamma: from discovery to a medicine at the FDA and beyond. Front Pharmacol. 2018;9:1093.
Article CAS PubMed PubMed Central Google Scholar
Richter B, Bandeira-Echtler E, Bergerhoff K, Clar C, Ebrahim SH. Pioglitazone for type 2 diabetes mellitus. Cochrane Database Syst Rev. 2006;2006(4):Cd006060.
PubMed PubMed Central Google Scholar
Nesti L, Tricò D, Mengozzi A, Natali A. Rethinking pioglitazone as a cardioprotective agent: a new perspective on an overlooked drug. Cardiovasc Diabetol. 2021;20(1):109.
Article CAS PubMed PubMed Central Google Scholar
Yi HJ, Lee JE, Lee DH, Kim YI, Cho CB, Kim IS, et al. The role of NLRP3 in traumatic brain injury and its regulation by pioglitazone. J Neurosurg. 2019. https://doi.org/10.3171/2019.6.JNS1954.
Zhang H, Huang C, Zhang D, Zhu Y. Pioglitazone protects against hypoxia-induced cardiomyocyte apoptosis through inhibiting NLRP3/caspase-1 pathway in vivo and in vitro. Int Heart J. 2022;63(5):893–903.
Article CAS PubMed Google Scholar
Chen W, Xi X, Zhang S, Zou C, Kuang R, Ye Z, et al. Pioglitazone Protects against renal ischemia-reperfusion injury via the AMP-activated protein kinase-regulated autophagy pathway. Front Pharmacol. 2018;9:851.
Article PubMed PubMed Central Google Scholar
Zou C, Zhou Z, Tu Y, Wang W, Chen T, Hu H. Pioglitazone attenuates reoxygenation injury in renal tubular NRK-52E cells exposed to high glucose via inhibiting oxidative stress and endoplasmic reticulum stress. Front Pharmacol. 2019;10:1607.
Article CAS PubMed Google Scholar
Acar M, Sayhan Kaplan H, Erdem AF, Tomak Y, Turan G, Özdin M. Effects of dexmedetomidine on new oxidative stress markers on renal ischaemia-reperfusion injury in rats: thiol/disulphide homeostasis and the ischaemia-modified albumin. Arch Physiol Biochem. 2022;128(4):1115–20.
Article CAS PubMed Google Scholar
Choi HY, Moon SJ, Ratliff BB, Ahn SH, Jung A, Lee M, et al. Microparticles from kidney-derived mesenchymal stem cells act as carriers of proangiogenic signals and contribute to recovery from acute kidney injury. PLoS ONE. 2014;9(2): e87853.
Article PubMed PubMed Central Google Scholar
Zheng Z, Xu K, Li C, Qi C, Fang Y, Zhu N, et al. NLRP3 associated with chronic kidney disease progression after ischemia/reperfusion-induced acute kidney injury. Cell death discovery. 2021;7(1):324.
Article CAS PubMed PubMed Central Google Scholar
Hu H, Zou C, Xi X, Shi Z, Wang G, Huang X. Protective effects of pioglitazone on renal ischemia-reperfusion injury in mice. J Surg Res. 2012;178(1):460–5.
Article CAS PubMed Google Scholar
Wolf P, Schoeniger A, Edlich F. Pro-apoptotic complexes of BAX and BAK on the outer mitochondrial membrane. Biochim Biophys Acta. 2022;1869(10): 119317.
Eskandari E, Eaves CJ. Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis. J Cell Biol. 2022;221(6):e202201159.
Article PubMed PubMed Central Google Scholar
Minutoli L, Puzzolo D, Rinaldi M, Irrera N, Marini H, Arcoraci V, et al. ROS-mediated NLRP3 inflammasome activation in brain, heart, kidney, and testis ischemia/reperfusion injury. Oxid Med Cell Longev. 2016;2016:2183026.
Article PubMed PubMed Central Google Scholar
Sharma BR, Kanneganti TD. NLRP3 inflammasome in cancer and metabolic diseases. Nat Immunol. 2021;22(5):550–9.
Article CAS PubMed PubMed Central Google Scholar
Tapia-Abellán A, Angosto-Bazarra D, Martínez-Banaclocha H, de Torre-Minguela C, Cerón-Carrasco JP, Pérez-Sánchez H, et al. MCC950 closes the active conformation of NLRP3 to an inactive state. Nat Chem Biol. 2019;15(6):560–4.
Article PubMed PubMed Central Google Scholar
Sharif H, Wang L, Wang WL, Magupalli VG, Andreeva L, Qiao Q, et al. Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome. Nature. 2019;570(7761):338–43.
Article CAS PubMed PubMed Central Google Scholar
Zhao M, Wang Y, Li L, Liu S, Wang C, Yuan Y, et al. Mitochondrial ROS promote mitochondrial dysfunction and inflammation in ischemic acute kidney injury by disrupting TFAM-mediated mtDNA maintenance. Theranostics. 2021;11(4):1845–63.
Article CAS PubMed PubMed Central Google Scholar
Tang C, Hu Y, Gao J, Jiang J, Shi S, Wang J, et al. Dexmedetomidine pretreatment attenuates myocardial ischemia reperfusion induced acute kidney injury and endoplasmic reticulum stress in human and rat. Life Sci. 2020;257: 118004.
Article CAS PubMed Google Scholar
Yang CC, Sung PH, Chiang JY, Chai HT, Chen CH, Chu YC, et al. Combined tacrolimus and melatonin effectively protected kidney against acute ischemia-reperfusion injury. FASEB J. 2021;35(6): e21661.
Article CAS PubMed Google Scholar
Liu X, Zhang P, Song X, Cui H, Shen W. PPARγ mediates protective effect against hepatic ischemia/reperfusion injury via NF-κB pathway. J Invest Surg. 2022;35(8):1648–59.
DeFronzo RA, Inzucchi S, Abdul-Ghani M, Nissen SE. Pioglitazone: the forgotten, cost-effective cardioprotective drug for type 2 diabetes. Diab Vasc Dis Res. 2019;16(2):133–43.
Article CAS PubMed Google Scholar
Betz B, Schneider R, Kress T, Schick MA, Wanner C, Sauvant C. Rosiglitazone affects nitric oxide synthases and improves renal outcome in a rat model of severe ischemia/reperfusion injury. PPAR Res. 2012;2012: 219319.
Article PubMed PubMed Central Google Scholar
Reel B, Guzeloglu M, Bagriyanik A, Atmaca S, Aykut K, Albayrak G, et al. The effects of PPAR-γ agonist pioglitazone on renal ischemia/reperfusion injury in rats. J Surg Res. 2013;182(1):176–84.
Article CAS PubMed Google Scholar
Ali SM, Khalifa H, Mostafa DK, El Sharkawy A. Suppression of connective tissue growth factor mediates the renoprotective effect of sitagliptin rather than pioglitazone in type 2 diabetes mellitus. Life Sci. 2016;153:180–7.
Article CAS PubMed Google Scholar
Xue Y, Enosi Tuipulotu D, Tan WH, Kay C, Man SM. Emerging activators and regulators of inflammasomes and pyroptosis. Trends Immunol. 2019;40(11):1035–52.
留言 (0)