Determination of HLA class II risk alleles and prediction of self/non-self-epitopes contributing Hashimoto’s thyroiditis in a group of Iranian patients

Al Yafei Z, Mack SJ, Alvares M, Ali BR, Afandi B, Beshyah SA, Sharma C, Osman W, Mirghani R, Nasr A, Al Remithi S, Al Jubeh J, Almawi WY, Alkaabi J, Elghazali G (2022) HLA-DRB1 and -DQB1 alleles, haplotypes and genotypes in Emirati patients with type 1 diabetes underscores the benefits of evaluating understudied populations. Front Genet 13:841879. https://doi.org/10.3389/fgene.2022.841879

Article  CAS  PubMed  PubMed Central  Google Scholar 

Antunes DA, Rigo MM, Freitas MV, Mendes MFA, Sinigaglia M, Lizée G, Kavraki LE, Selin LK, Cornberg M, Vieira GF (2017) Interpreting T-cell cross-reactivity through structure: implications for TCR-based cancer immunotherapy. Front Immunol 8:1210. https://doi.org/10.3389/fimmu.2017.01210

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arango MT, Perricone C, Kivity S, Cipriano E, Ceccarelli F, Valesini G, Shoenfeld Y (2017) HLA-DRB1 the notorious gene in the mosaic of autoimmunity. Immunol Res 65:82–98. https://doi.org/10.1007/s12026-016-8817-7

Article  CAS  PubMed  Google Scholar 

Baker S, Miguel RN, Thomas D, Powell M, Furmaniak J, Smith BR (2023) Cryo-electron microscopy structures of human thyroid peroxidase (TPO) in complex with TPO antibodies. J Mol Endocrinol 70(3). https://doi.org/10.1530/jme-22-0149

Bodis G, Toth V, Schwarting A (2018) Role of human leukocyte antigens (HLA) in autoimmune diseases. Rheumatol Ther 5:5–20. https://doi.org/10.1007/s40744-018-0100-z

Article  PubMed  PubMed Central  Google Scholar 

Bogers L, Kuiper KL, Smolders J, Rip J, Van Luijn MM (2023) Epstein-Barr virus and genetic risk variants as determinants of T-bet(+) b cell-driven autoimmune diseases. Immunol Lett 261:66–74. https://doi.org/10.1016/j.imlet.2023.07.006

Article  CAS  PubMed  Google Scholar 

Caturegli P, De Remigis A, Rose NR (2014) Hashimoto thyroiditis: clinical and diagnostic criteria. Autoimmun Rev 13:391–397. https://doi.org/10.1016/j.autrev.2014.01.007

Article  CAS  PubMed  Google Scholar 

Cho WK, Jung MH, Choi EJ, Choi HB, Kim TG, Suh BK (2011) Association of HLA alleles with autoimmune thyroid disease in Korean children. Horm Res Paediatr 76:328–334. https://doi.org/10.1159/000331134

Article  CAS  PubMed  Google Scholar 

Choi YM, Kim TY, Kim EY, Jang EK, Jeon MJ, Kim WG, Shong YK, Kim WB (2017) Association between thyroid autoimmunity and helicobacter pylori infection. Korean j Intern Med 32:309–313. https://doi.org/10.3904/kjim.2014.369

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cuan-Baltazar Y, Soto-Vega E (2020) Microorganisms associated to thyroid autoimmunity. Autoimmun Rev 19:102614. https://doi.org/10.1016/j.autrev.2020.102614

Article  CAS  PubMed  Google Scholar 

Enz LS, Zeis T, Schmid D, Geier F, Van Der Meer F, Steiner G, Certa U, Binder TMC, Stadelmann C, Martin R, Schaeren-Wiemers N (2020) Increased HLA-DR expression and cortical demyelination in MS links with HLA-DR15. Neurol Neuroimmunol Neuroinflamm 7(2). https://doi.org/10.1212/nxi.0000000000000656

Farid NR, Thompson C (1986) HLA and autoimmune endocrine disease 1985. Mol Biol Med 3:85–97

CAS  PubMed  Google Scholar 

Figura N, Di Cairano G, Moretti E, Iacoponi F, Santucci A, Bernardini G, Gonnelli S, Giordano N, Ponzetto A (2019) Helicobacter pylori infection and autoimmune thyroid diseases: the role of virulent strains. Antibiotics (Basel) 9(1). https://doi.org/10.3390/antibiotics9010012

Ghobadi MZ, Izadi S, Teymoori-Rad M, Farahmand M, Mozhgani SH, Labbaf N, Shokri F, Marashi SM (2021) Potential role of viral infection and B cells as a linker between innate and adaptive immune response in systemic lupus erythematosus. Immunol Res 69:196–204. https://doi.org/10.1007/s12026-021-09186-4

Article  CAS  PubMed  Google Scholar 

Hammerstad SS, Jahnsen FL, Tauriainen S, Hyöty H, Paulsen T, Norheim I, Dahl-Jørgensen K (2013) Inflammation and increased myxovirus resistance protein A expression in thyroid tissue in the early stages of Hashimotoʼs thyroiditis. Thyroid 23:334–341. https://doi.org/10.1089/thy.2012.0264

Article  CAS  PubMed  Google Scholar 

Hasham A, Tomer Y (2012) Genetic and epigenetic mechanisms in thyroid autoimmunity. Immunol Res 54:204–213. https://doi.org/10.1007/s12026-012-8302-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

He W, Zhao J, Liu X, Li S, Mu K, Zhang J, Zhang JA (2021) Associations between CD160 polymorphisms and autoimmune thyroid disease: a case-control study. Bmc Endocr Disord 21:148. https://doi.org/10.1186/s12902-021-00810-w

Article  CAS  PubMed  PubMed Central  Google Scholar 

Katahira M, Hanakita M, Ito T, Suzuki M (2013) Effect of human leukocyte antigen class II genes on Hashimotoʼs thyroiditis requiring replacement therapy with levothyroxine in the Japanese population. Hum Immunol 74:607–609. https://doi.org/10.1016/j.humimm.2013.01.026

Article  CAS  PubMed  Google Scholar 

Kokaraki G, Daniilidis M, Yiangou M, Arsenakis M, Karyotis N, Tsilipakou M, Fleva A, Gerofotis A, Karadani N, Yovos JG (2009) Major histocompatibility complex class II (DRB1*, DQA1*, and DQB1*) and DRB1*04 subtypesʼ associations of Hashimotoʼs thyroiditis in a Greek population. Tissue Antigens 73:199–205. https://doi.org/10.1111/j.1399-0039.2008.01182.x

Article  CAS  PubMed  Google Scholar 

Koukoulitsa C, Chontzopoulou E, Kiriakidi S, Tzakos AG, Mavromoustakos T (2020) A journey to the conformational analysis of T-cell epitope peptides involved in multiple sclerosis. Brain Sci 10(6). https://doi.org/10.3390/brainsci10060356

Laron Z, Shulman L, Hampe C, Blumenfeld O (2023) Hypothesis: viral infections of pregnant women may be early triggers of childhood type 1 diabetes and other autoimmune disease. J Autoimmun 135:102977. https://doi.org/10.1016/j.jaut.2022.102977

Article  CAS  PubMed  Google Scholar 

Lee HJ, Stefan-Lifshitz M, Li CW, Tomer Y (2023) Genetics and epigenetics of autoimmune thyroid diseases: translational implications. Best Pract Res Clin Endocrinol Metab 37:101661. https://doi.org/10.1016/j.beem.2022.101661

Article  CAS  PubMed  Google Scholar 

Liontiris MI, Mazokopakis EE (2017) A concise review of Hashimoto thyroiditis (HT) and the importance of iodine, selenium, vitamin D and gluten on the autoimmunity and dietary management of HT patients. Points that need more investigation. Hell j Nucl Med 20:51–56. https://doi.org/10.1967/s002449910507

Article  PubMed  Google Scholar 

Martins YC, Jurberg AD, Daniel-Ribeiro CT (2023) Visiting molecular mimicry once more: pathogenicity, virulence, and autoimmunity. Microorganisms 11(6). https://doi.org/10.3390/microorganisms11061472

Moghadam M, Ghaemi EA, Akbari H, Razavi Nikoo H, Zamani S (2022) Mycobacterium avium subsp. Paratuberculosis and Hashimotoʼs thyroiditis: is map the trigger? Front cell infect microbiol 12:972929. https://doi.org/10.3389/fcimb.2022.972929

Article  CAS  PubMed  Google Scholar 

Moradi MT, Yari K, Khodarahmi R (2014) A novel, efficient, fast and inexpensive DNA extraction protocol from whole blood applicable for studying drug-DNA interaction. J Rep Pharm Sci 3:80–84

Article  Google Scholar 

Naito T, Okada Y (2022) HLA imputation and its application to genetic and molecular fine-mapping of the MHC region in autoimmune diseases. Semin Immunopathol 44:15–28. https://doi.org/10.1007/s00281-021-00901-9

Article  CAS  PubMed  Google Scholar 

Nekoua MP, Alidjinou EK, Hober D (2022) Persistent coxsackievirus B infection and pathogenesis of type 1 diabetes mellitus. Nat Rev Endocrinol 18:503–516. https://doi.org/10.1038/s41574-022-00688-1

Article  CAS  PubMed  PubMed Central  Google Scholar 

Painter CA, Stern LJ (2012) Conformational variation in structures of classical and non-classical MHCII proteins and functional implications. Immunol Rev 250:144–157. https://doi.org/10.1111/imr.12003

Article  CAS  PubMed  PubMed Central  Google Scholar 

Petrone A, Giorgi G, Mesturino CA, Capizzi M, Cascino I, Nistico L, Osborn J, Di mario U, Buzzetti R (2001) Association of DRB1*04-DQB1*0301 haplotype and lack of association of two polymorphic sites at CTLA-4 gene with Hashimotoʼs thyroiditis in an Italian population. Thyroid 11:171–175. https://doi.org/10.1089/105072501300042901

Article  CAS  PubMed  Google Scholar 

Qu HQ, Qu J, Bradfield J, Glessner J, Chang X, March M, Mentch FD, Roizen JD, Connolly JJ, Sleiman P, Hakonarson H (2021) Combined application of genetic and polygenic risk scores for type 1 diabetes risk prediction. Diabetes Obes Metab 23:2001–2003. https://doi.org/10.1111/dom.14419

Article  PubMed  PubMed Central  Google Scholar 

Ralli M, Angeletti D, Fiore M, D’aguanno V, Lambiase A, Artico M, De Vincentiis M, Greco A (2020) Hashimotoʼs thyroiditis: an update on pathogenic mechanisms, diagnostic protocols, therapeutic strategies, and potential malignant transformation. Autoimmun Rev 19:102649. https://doi.org/10.1016/j.autrev.2020.102649

Article  CAS  PubMed  Google Scholar 

Ramasamy R, Mohammed F, Meier UC (2020) HLA DR2B-binding peptides from human endogenous retrovirus envelope, Epstein-Barr virus and brain proteins in the context of molecular mimicry in multiple sclerosis. Immunol Lett 217:15–24. https://doi.org/10.1016/j.imlet.2019.10.017

Article  CAS  PubMed  Google Scholar 

Rasouli-Saravani A, Tahamoli-Roudsari A, Basiri Z, Babaei M, Fazaeli A, Roshanaei G, Hajilooi M, Solgi G (2021) Relevance of autoantibody profile with Hla-Drb1 and -DQB1 alleles in a group of Iranian systemic lupus erythematosus patients. Immunol Lett 237:11–16. https://doi.org/10.1016/j.imlet.2021.06.004

Article  CAS  PubMed  Google Scholar 

Rastogi I, Jeon D, Moseman JE, Muralidhar A, Potluri HK, Mcneel DG (2022) Role of B cells as antigen presenting cells. Front Immunol 13:954936. https://doi.org/10.3389/fimmu.2022.954936

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schultheiss UT, Teumer A, Medici M, Li Y, Daya N, Chaker L, Homu

留言 (0)

沒有登入
gif