We have perused a research article entitled “Prevalence and Risk Factors of Chronic Obstructive Pulmonary Disease Among Users of Primary Health Care Facilities in Morocco” by Al wachami et al.1 It is a very valuable and meaningful study. We congratulate the authors of this good paper. The strengths of this study are as follows: (1) Chronic obstructive pulmonary disease (COPD) remains an under-diagnosed disease in the world and Morocco,1,2 which poses a great challenge to its prevention and management. This study is the first to determine the prevalence of COPD based on spirometry and identify its risk factors among users of primary health care facilities in Settat, Morocco. It has played an important role in understanding the epidemiology of COPD in Morocco, such as the prevalence and contributing factors of COPD; (2) This study provides clear and reliable diagnostic criteria for COPD, the authors diagnose COPD based on the Global Initiative for Obstructive Lung Disease (GOLD) criteria, which is the most widely used and effective method;3 (3) This study explores multifaceted risk factors related to COPD in Morocco, eg, socio-demographic factors, respiratory symptoms, potential COPD risk factors, comorbidities, etc. In addition, this study provides a very clear definition or explanation for some risk factors, such as smoking status, occupational exposure and biomass exposure; (4) The authors conducted in-depth discussion on their research findings and fully compared them with other similar studies, and analyzed the specific reasons for these discrepancies. Additionally, the authors also provided some public health policy recommendations for the prevention and management of COPD.

However, this study has also encountered certain constraints and several areas that need to be improved in the future, namely: (1) Regarding the risk factors associated with COPD, the authors may consider using Chi-square test to conduct univariate analysis; (2) There are three areas in the text that need to be corrected: (a) Page 377, regarding the description of “The average number of packs smoked per year was 4.97 ± 15.13”, since the mean is less than the standard deviation, we suggest that the authors use the median (M) and interquartile range (IQR) to describe the distribution characteristic of this variable. (b) Page 381, regarding the description of “The total prevalence of COPD in the 40–49 age group was 3.3%, and reached 16.9% among people aged 70 and over (p = 0.001)”, the p-value is inconsistent with the results in Table 3 of page 381. The corrigendum is shown in Table 1 of our letter. (c) Page 383, the description of “In univariate analysis, we observed that gender, age, low level of education, body mass index, smoking, childhood exposure to tobacco smoke, family history of respiratory disease, previous diagnosis of asthma and childhood hospitalization for lung disease were significantly associated with COPD “is inconsistent with the results in Table 3 of page 381–383. “Body mass index” and “childhood exposure to tobacco smoke” were not associated with COPD (p > 0.05); However, this limitation can be resolved by incorporating factors with p-values less than 0.1 or 0.2 in univariate analysis into multivariate analysis; (3) The authors did not include all the general characteristics of the study sample in the univariate analysis, eg, employment. Additionally, Atassi reported a statistically significant association between low socio-economic status and COPD.4 Thus, the authors can incorporate these factors into the analysis in future research to identify more comprehensive risk factors related to COPD; (4) This study was only conducted in the Settat region of Morocco, so the conclusion cannot represent the overall situation of COPD in Morocco.

Table 1 Prevalence of COPD According to Studied Factors (N = 477)

To obtain more accurate and reliable results, we recommend that further study be carried out by (1) Collaborate with primary healthcare establishments in other regions of Morocco (eg, Tangier, Rabat, Casablanca, Marrakech, Meknes, Fez, Agadir, etc.) to conduct large-scale and multicenter studies to draw convincing conclusions; (2) The development of an effective questionnaire/scale to screen for COPD is necessary to promote early detection of this disease; (3) In future research, a control group can be established to compare the differences of COPD situation (eg, prevalence, risk factors) among different populations; (4) Work to establish a predictive model regarding the prevalence and risk factors of COPD based on medical big data and methods such as machine learning is essential for early precise screening of patients, and to develop appropriate and timely prevention and management strategies, and reduce the disease burden on a national scale in Morocco.

We thank all the authors of the original article titled “Prevalence and Risk Factors of Chronic Obstructive Pulmonary Disease Among Users of Primary Health Care Facilities in Morocco”. We have learned a lot of valuable knowledge from their article.

The authors report no conflicts of interest in this communication.

1. Al Wachami N, Arraji M, Iderdar Y, et al. Prevalence and risk factors of chronic obstructive pulmonary disease among users of primary health care facilities in Morocco. Int J Chron Obstruct Pulmon Dis. 2024;19:375–387. doi:10.2147/COPD.S443081

2. Varmaghani M, Dehghani M, Heidari E, Sharifi F, Moghaddam SS, Farzadfar F. Global prevalence of chronic obstructive pulmonary disease: systematic review and meta-analysis. East Mediterr Health J. 2019;25(1):47–57. doi:10.26719/emhj.18.014

3. Celli B, Fabbri L, Criner G, et al. Definition and nomenclature of chronic obstructive pulmonary disease: time for its revision. Am J Respir Crit Care Med. 2022;206(11):1317–1325. doi:10.1164/rccm.202204-0671PP

4. Atassi M, Kava A, Nejjari C, et al. Association between chronic airflow obstruction and socio-economic position in Morocco: bold results. Int J Tuberc Lung Dis. 2020;24(2):202–206. doi:10.5588/ijtld.19.0170