Sturgis R, Mack A, Kim S, Maier J, Heath EI (2021) Symptom outcomes of Cancer patients with clival metastases treated with Radiotherapy: a study of 44 patients. Anticancer Res 41:5001–5006. https://doi.org/10.21873/anticanres.15314

Article  PubMed  Google Scholar 

Jozsa F, Das JM (2022) Metastatic lesions of the Clivus: a systematic review. World Neurosurg 158:190–204. https://doi.org/10.1016/j.wneu.2021.11.105

Article  PubMed  Google Scholar 

Wei Z, Yavan S, Deng H, Mallela AN, Gersey ZC, Shariff RK, Fazeli PK, Niranjan A, Lunsford LD, Abou-Al-Shaar H (2022) The role of stereotactic radiosurgery in the multidisciplinary management of pituitary metastases. Pituitary 25:948–958. https://doi.org/10.1007/s11102-022-01279-z

Article  PubMed  Google Scholar 

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71. https://doi.org/10.1136/bmj.n71

Article  PubMed  PubMed Central  Google Scholar 

OCEBM OCEBM Levels of Evidence https://www.cebm.net/index.aspx?o=5653

Agha RA, Sohrabi C, Mathew G, Franchi T, Kerwan A, O’Neill N, Thoma A, Beamish AJ, Noureldin A, Rao A, Vasudevan B, Challacombe B, Perakath B, Kirshtein B, Ekser B, Pramesh CS, Laskin DM, Machado-Aranda D, Pagano D, Roy G, Kadioglu H, Nixon IJ, Mukhejree I, McCaul JA, Chi-Yong Ngu J, Albrecht J, Rivas JG, Raveendran K, Derbyshire L, Ather MH, Thorat MA, Valmasoni M, Bashashati M, Chalkoo M, Teo NZ, Raison N, Muensterer OJ, Bradley PJ, Goel P, Pai PS, Afifi RY, Rosin RD, Coppola R, Klappenbach R, Wynn R, Surani S, Giordano S, Massarut S, Raja SG, Basu S, Enam SA, Manning TG, Cross T, Karanth VKL, Mei Z (2020) The PROCESS 2020 Guideline: updating Consensus Preferred reporting of CasE series in surgery (PROCESS) guidelines. Int J Surg 84:231–235. https://doi.org/10.1016/j.ijsu.2020.11.005

Article  PubMed  Google Scholar 

Alessi G, Lemmerling M, Vereecken L, De Waele L (2003) Benign metastasizing leiomyoma to skull base and spine: a report of two cases. Clin Neurol Neurosurg 105:170–174. https://doi.org/10.1016/s0303-8467(03)00002-7

Article  PubMed  Google Scholar 

Atallah-Yunes SA, Clark J, Samanani S, Soe M (2019) Small cell Lung Cancer with Pituitary Metastasis presenting as secondary adrenal insufficiency: a Case Report and Literature Review. Am J Case Rep 20:207–211. https://doi.org/10.12659/ajcr.913388

Article  PubMed  PubMed Central  Google Scholar 

Barrière J, Thariat J, Vandenbos F, Bondiau PY, Peyrottes I, Peyrade F (2009) Diplopia as the first symptom of an aggressive metastatic rectal stromal tumor. Onkologie 32:345–347. https://doi.org/10.1159/000215712

Article  PubMed  Google Scholar 

Bohnstedt BN, Tomcik M, Eads T, Hagen MC, Shah M (2012) Metastasis of soft-tissue myoepithelial carcinoma to clivus. J Neurosurg Pediatr 9:161–164. https://doi.org/10.3171/2011.11.Peds11260

Article  PubMed  Google Scholar 

Deconde AS, Sanaiha Y, Suh JD, Bhuta S, Bergsneider M, Wang MB (2013) Metastatic disease to the clivus mimicking clival chordomas. J Neurol Surg B Skull Base 74:292–299. https://doi.org/10.1055/s-0033-1348027

Article  PubMed  PubMed Central  Google Scholar 

Dekker SE, Wasman J, Yoo KK, Alonso F, Tarr RW, Bambakidis NC, Rodriguez K (2017) Clival metastasis of a duodenal adenocarcinoma: a Case Report and Literature Review. World Neurosurg 100:62–68. https://doi.org/10.1016/j.wneu.2016.12.078

Article  PubMed  Google Scholar 

Douglas JE, Lee JYK, Rajasekaran K (2020) Cranial nerve VI Palsy as Presenting sign of previously undiagnosed metastatic prostate adenocarcinoma to the Clivus. Biomed Hub 5:210–213. https://doi.org/10.1159/000510303

Article  PubMed  PubMed Central  Google Scholar 

Endo K, Okano R, Kuroda Y, Yamada S, Tabei K (2001) Renal cell carcinoma with skull base metastasis preceded by paraneoplastic signs in a chronic hemodialysis patient. Intern Med 40:924–930. https://doi.org/10.2169/internalmedicine.40.924

Article  CAS  PubMed  Google Scholar 

Fukushima M, Katayama Y, Shigemori Y, Miyake H, Hirayama T, Kotani A (2012) Clivus metastasis from gastric signet ring cell carcinoma after a 10-year disease-free interval–case report. Neurol Med Chir (Tokyo) 52:751–753. https://doi.org/10.2176/nmc.52.751

Article  PubMed  Google Scholar 

Ho KWD, Drew PA, Chuquilin M (2017) Merkel Cell Carcinoma with distant metastasis to the Clivus causing symptoms mimicking Tolosa-Hunt Syndrome: a Case Report and Literature Review. Front Neurol 8:409. https://doi.org/10.3389/fneur.2017.00409

Article  PubMed  PubMed Central  Google Scholar 

Hooker N, Mohanan S, Burks RT (2018) A Rare Presentation of Stage IV Large Cell Neuroendocrine Carcinoma of the Cervix with Metastasis to the Cranium. Case Rep Obstet Gynecol 2018: 2812306 https://doi.org/10.1155/2018/2812306

Isaka T, Maruno M, Suzuki T, Sato M, Yoshimine T (2006) Skull metastases from atypical pulmonary carcinoid tumor in a 19-year-old man. Neurol Med Chir (Tokyo) 46:609–613. https://doi.org/10.2176/nmc.46.609

Article  PubMed  Google Scholar 

Kapoor A, Beniwal V, Beniwal S, Mathur H, Kumar HS (2015) Isolated clival metastasis as the cause of abducens nerve palsy in a patient of breast carcinoma: a rare case report. Indian J Ophthalmol 63:354–357. https://doi.org/10.4103/0301-4738.158096

Article  PubMed  PubMed Central  Google Scholar 

Kocak Z, Celik Y, Uzal MC, Uygun K, Kaya M, Albayram S (2003) Isolated bilateral sixth nerve palsy secondary to metastatic carcinoma: a case report with a review of the literature. Clin Neurol Neurosurg 106:51–54. https://doi.org/10.1016/j.clineuro.2003.07.002

Article  PubMed  Google Scholar 

Kolias AG, Derham C, Mankad K, Hasegawa H, O’Kane R, Ismail A, Phillips NI (2010) Multiple cranial neuropathy as the initial presentation of metastatic prostate adenocarcinoma: case report and review of literature. Acta Neurochir 152:1251–1255. https://doi.org/10.1007/s00701-010-0630-9

Article  PubMed  Google Scholar 

Lee A, Chang KH, Hong H, Kim H (2015) Sixth cranial nerve palsy caused by gastric adenocarcinoma metastasis to the clivus. J Korean Neurosurg Soc 57:208–210. https://doi.org/10.3340/jkns.2015.57.3.208

Article  CAS  PubMed  PubMed Central  Google Scholar 

Machío Castelló M, Escobar Montatixe D, Cenjor Español C, Villacampa Aubá JM, Montoya Bordón J, Carias Calix R, Sáez Pinel R (2017) Incomplete cavernous sinus syndrome as the initial manifestation of a previously undetected metastatic prostate adenocarcinoma. Head Neck 39:E77–e80. https://doi.org/10.1002/hed.24808

Article  PubMed  Google Scholar 

McDermott RS, Anderson PR, Greenberg RE, Milestone BN, Hudes GR (2004) Cranial nerve deficits in patients with metastatic prostate carcinoma: clinical features and treatment outcomes. Cancer 101:1639–1643. https://doi.org/10.1002/cncr.20553

Article  PubMed  Google Scholar 

Ng ES, Tan SH, Ling WH, Venkatesh SK, Wong CI (2011) Ophthalmoplegia in a patient with breast cancer. Ann Acad Med Singap 40:507–509

Article  PubMed  Google Scholar 

Nozaki I, Tsukada T, Nakamura Y, Takanaka T, Yamada M (2010) Multiple skull metastases from hepatocellular carcinoma successfully treated with radiotherapy. Intern Med 49:2631–2634. https://doi.org/10.2169/internalmedicine.49.4236

Article  PubMed  Google Scholar 

Ogunlaja O, Zhang N (2019) New Daily Persistent Headache Syndrome secondary to Clival Metastasis within an Osseous Hemangioma. Headache 59:1609–1610. https://doi.org/10.1111/head.13655

Article  PubMed  Google Scholar 

Pallini R, Sabatino G, Doglietto F, Lauretti L, Fernandez E, Maira G (2009) Clivus metastases: report of seven patients and literature review. Acta Neurochir 151:291–296. https://doi.org/10.1007/s00701-009-0229-1

Article  PubMed  Google Scholar 

Rao AS, Nandennavar M, Narayanan GS (2015) Carcinoma cervix presenting with clivus metastasis. J Cancer Res Ther 11:662. https://doi.org/10.4103/0973-1482.138192

Article  PubMed  Google Scholar 

Sako K, Kimura T, Sawamura A, Yonemasu Y, Takahashi M, Miyokawa N (1997) Prevention of CSF Leakage by staged operation for Clival metastatic tumor. Skull Base Surg 7:159–162. https://doi.org/10.1055/s-2008-1058608

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tsunoda A, Tanaka Y, Sato T, Kirimura S, Kitamura K (2016) Vertigo by breast Cancer metastasis 33 years after treatment. Intern Med 55:311–313. https://doi.org/10.2169/internalmedicine.55.5412

Article  CAS  PubMed  Google Scholar 

Turner JL, Sweeney P, Hardy R (1980) Ewing’s tumor metastatic to the clivus, simulating meningitis: case report. Neurosurgery 7:619–620. https://doi.org/10.1227/00006123-198012000-00017

Article  CAS  PubMed  Google Scholar 

Yari N, Espino Barros Palau A, Morgan ML, Levine NB, Lee AG (2016) Metastatic papillary thyroid carcinoma presenting as Abducens Palsy complicated by Ocular Neuromyotonia. Neuroophthalmology 40:97–101. https://doi.org/10.3109/01658107.2015.1132742

Article  PubMed  PubMed Central  Google Scholar 

Yoshikawa-Kimura A, Taira K, Katanosaka Y, Nakata A, Nadatani Y, Fukunaga S, Otani K, Hosomi S, Tanaka F, Kamata N, Nagami Y, Watanabe T, Fujiwara Y (2020) A rare case of Clival Metastasis in a patient with gastric Cancer. Intern Med 59:3161–3164. https://doi.org/10.2169/internalmedicine.5457-20

Article  PubMed  PubMed Central  Google Scholar 

Zagzoog N, Ra G, Koziarz A, Provias J, Sommer D, Almenawer SA, Reddy K (2017) Metastatic liposarcoma of the Skull Base: a Case Report and Review of Literature. Neurosurgery 80:219–223. https://doi.org/10.1093/neuros/nyw157