Regulatory Insights into Nanomedicine and Gene Vaccine Innovation: Safety Assessment, Challenges, and Regulatory Perspectives

Keywords

Nanomedicines

Gene vaccines

Regulatory issues

Safety assessment

Intellectual property rights

Ethical considerations

List of AbbreviationsADR

Adverse Drug Reactions

APCs

Antigen Presenting Cells

COVID-19

Corona Virus Disease 2019

CTAB

Cetyltrimethylammonium Bromide

CTLs

Cytotoxic T-lymphocytes

cryo-TEM

Cryo-Transmission Electron Microscopy

DOTAP

Dioleoyl-3-Trimethylammonium Propane

E1

E1A, E1B E2, E3, E4, Early Regions of Adeno Virus

E4ORF3

E4ORF6, Early Region and Open Reading Frames of Adeno Virus

EMA

European Medicines Agency

FAS-ligand

Ligand for Subgroup of TNF-R

FDA

Food and Drug Administration

FFP

Freedom From Progression

HSPGs

Heparan sulfate proteoglycans

ISGF3

Interferon-Stimulated Gene Factor 3

LPHNs

Lipid-Polymer Hybrid Nanoparticles

MHC

Major Histocompatibility Complex

MRI

Magnetic Resonance Imaging

mRNA

Messenger Ribonucleic Acid

NF-κB

Nuclear Factor Kappa B

NLCs

Nanostructured Lipid Carriers

NSCLC

Non-Small Cell Lung Cancer

PDT

Photodynamic Therapies

PEG

Poly-(ethylene glycol)

PEG-PE

Poly-(ethylene glycol)-phosphatidylethanolamine

PFS

Progression Free Survival

PHLNPs

Polymer-lipid hybrid nanoparticles

PLGA

Poly-D,L-lactide-co-glycolide

PTT

Photothermal Treatments

pRB

Retinoblastoma Protein

RES

Retinal Endothelial System

RFS

Recurrence-Free Survival

SANS

Small Angle Neutron Scattering

SAXS

Small Angle X-Ray Scattering

SCLC

Small Cell Lung Cancer

SLNs

Solid Lipid Nanoparticles

TERT

Telomerase Reverse Transcriptase

TNF-α

Tumour Necrosis Factor

留言 (0)

沒有登入
gif