Forfia PR, Vaidya A, Wiegers SE. Pulmonary heart disease: The heart-lung interaction and its impact on patient phenotypes. Pulm Circ. 2013;3:5–19.
Article CAS PubMed PubMed Central Google Scholar
Agusti A, Hogg JC. Update on the pathogenesis of chronic obstructive pulmonary disease. N Engl J Med. 2019;381:1248–56.
Article CAS PubMed Google Scholar
Qi H, Liu H, Pullamsetti SS, Gunther S, Kuenne C, Atzberger A, et al. Epigenetic regulation by Suv4-20h1 in cardiopulmonary progenitor cells is required to prevent pulmonary hypertension and chronic obstructive pulmonary disease. Circulation. 2021;144:1042–58.
Article CAS PubMed Google Scholar
Hoang T, Wang J, Boyd P, Wang F, Santiago C, Jiang L, et al. Gene regulatory networks controlling vertebrate retinal regeneration. Science. 2020;370:eabb8598.
Article CAS PubMed PubMed Central Google Scholar
Jorstad NL, Wilken MS, Grimes WN, Wohl SG, VandenBosch LS, Yoshimatsu T, et al. Stimulation of functional neuronal regeneration from Muller glia in adult mice. Nature. 2017;548:103–7.
Article CAS PubMed PubMed Central Google Scholar
Wang JL, Jiang XY, Zhao LX, Zuo SJ, Chen XT, Zhang LM, et al. Lineage reprogramming of fibroblasts into induced cardiac progenitor cells by CRISPR/Cas9-based transcriptional activators. Acta Pharm Sin B. 2020;10:313–26.
Lalit PA, Salick MR, Nelson DO, Squirrell JM, Shafer CM, Patel NG, et al. Lineage reprogramming of fibroblasts into proliferative induced cardiac progenitor cells by defined factors. Cell Stem Cell. 2016;18:354–67.
Article CAS PubMed PubMed Central Google Scholar
Zhang Y, Cao N, Huang Y, Spencer CI, Fu JD, Yu C, et al. Expandable cardiovascular progenitor cells reprogrammed from fibroblasts. Cell Stem Cell. 2016;18:368–81.
Article CAS PubMed PubMed Central Google Scholar
Miyajima A, Tanaka M, Itoh T. Stem/progenitor cells in liver development, homeostasis, regeneration, and reprogramming. Cell Stem Cell. 2014;14:561–74.
Article CAS PubMed Google Scholar
Peng T, Tian Y, Boogerd CJ, Lu MM, Kadzik RS, Stewart KM, et al. Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor. Nature. 2013;500:589–92.
Article CAS PubMed PubMed Central Google Scholar
Steimle JD, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, et al. Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development. Proc Natl Acad Sci USA. 2018;115:E10615–E24.
Article CAS PubMed PubMed Central Google Scholar
Liang S, Li HC, Wang YX, Wu SS, Cai YJ, Cui HL, et al. Pulmonary endoderm, second heart field and the morphogenesis of distal outflow tract in mouse embryonic heart. Dev Growth Differ. 2014;56:276–92.
Article CAS PubMed Google Scholar
Hatzistergos KE, Durante MA, Valasaki K, Wanschel A, Harbour JW, Hare JM. A novel cardiomyogenic role for Isl1+ neural crest cells in the inflow tract. Sci Adv. 2020;6:eaba9950.
Article CAS PubMed PubMed Central Google Scholar
Zhou L, Liu J, Xiang M, Olson P, Guzzetta A, Zhang K, et al. Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation. Proc Natl Acad Sci USA. 2017;114:E1422–E31.
Article CAS PubMed PubMed Central Google Scholar
Zhang C, Li Y, Cao J, Yu B, Zhang K, Li K, et al. Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation. Open Biol. 2021;11:210020.
Article CAS PubMed PubMed Central Google Scholar
Hrycaj SM, Dye BR, Baker NC, Larsen BM, Burke AC, Spence JR, et al. Hox5 genes regulate the Wnt2/2b-Bmp4-signaling axis during lung development. Cell Rep. 2015;12:903–12.
Article CAS PubMed PubMed Central Google Scholar
Arora R, Metzger RJ, Papaioannou VE. Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system. PLoS Genet. 2012;8:e1002866.
Article CAS PubMed PubMed Central Google Scholar
Rankin SA, Steimle JD, Yang XH, Rydeen AB, Agarwal K, Chaturvedi P, et al. Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development. Elife. 2021;10:e69288.
Article CAS PubMed PubMed Central Google Scholar
Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, et al. The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med. 1994;149:818–24.
Article CAS PubMed Google Scholar
Favarin DC, de Oliveira JR, de Oliveira CJ, Rogerio Ade P. Potential effects of medicinal plants and secondary metabolites on acute lung injury. Biomed Res Int. 2013;2013:576479.
Vahdat S, Pahlavan S, Mahmoudi E, Barekat M, Ansari H, Bakhshandeh B, et al. Expansion of human pluripotent stem cell-derived early cardiovascular progenitor cells by a cocktail of signaling factors. Sci Rep. 2019;9:16006.
Article PubMed PubMed Central Google Scholar
Ng WH, Johnston EK, Tan JJ, Bliley JM, Feinberg AW, Stolz DB, et al. Recapitulating human cardio-pulmonary co-development using simultaneous multilineage differentiation of pluripotent stem cells. Elife. 2022;11:e67872.
Article CAS PubMed PubMed Central Google Scholar
Ng WH, Varghese B, Ren X. Co-differentiation and co-maturation of human cardio-pulmonary progenitors and micro-tissues from human induced pluripotent stem cells. Bio Protoc. 2022;12:e4488.
Article CAS PubMed PubMed Central Google Scholar
Liang L, Xu W, Shen A, Fu X, Cen H, Wang S, et al. Inhibition of YAP1 activity ameliorates acute lung injury through promotion of M2 macrophage polarization. MedComm (2020). 2023;4:e293.
Zeng Z, Xia L, Fan X, Ostriker AC, Yarovinsky T, Su M, et al. Platelet-derived miR-223 promotes a phenotypic switch in arterial injury repair. J Clin Invest. 2019;129:1372–86.
Article PubMed PubMed Central Google Scholar
Penalosa-Ruiz G, Bright AR, Mulder KW, Veenstra GJC. The interplay of chromatin and transcription factors during cell fate transitions in development and reprogramming. Biochim Biophys Acta Gene Regul Mech. 2019;1862:194407.
Article CAS PubMed Google Scholar
Steimle JD, Moskowitz IP. TBX5: A key regulator of heart development. Curr Top Dev Biol. 2017;122:195–221.
Article CAS PubMed Google Scholar
Li T, He Z, Zhang X, Tian M, Jiang K, Cheng G, et al. The status of MAPK cascades contributes to the induction and activation of Gata4 and Nkx2.5 during the stepwise process of cardiac differentiation. Cell Signal. 2019;54:17–26.
Article CAS PubMed Google Scholar
Jumppanen M, Kinnunen SM, Valimaki MJ, Talman V, Auno S, Bruun T, et al. Synthesis, identification, and structure-activity relationship analysis of GATA4 and NKX2-5 protein-protein interaction modulators. J Med Chem. 2019;62:8284–310.
Article CAS PubMed PubMed Central Google Scholar
Atkins MH, Scarfo R, McGrath KE, Yang D, Palis J, Ditadi A, et al. Modeling human yolk sac hematopoiesis with pluripotent stem cells. J Exp Med. 2022;219:e20211924.
Article CAS PubMed Google Scholar
Islas JF, Liu Y, Weng KC, Robertson MJ, Zhang S, Prejusa A, et al. Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors. Proc Natl Acad Sci USA. 2012;109:13016–21.
Article CAS PubMed PubMed Central Google Scholar
Ha DH, Kim HK, Lee J, Kwon HH, Park GH, Yang SH, et al. Mesenchymal stem/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration. Cells. 2020;9:1157.
Article CAS PubMed PubMed Central Google Scholar
Xing Z, Zhao C, Liu H, Fan Y. Endothelial progenitor cell-derived extracellular vesicles: a novel candidate for regenerative medicine and disease treatment. Adv Health Mater. 2020;9:e2000255.
Jung JH, Fu X, Yang PC. Exosomes generated from iPSC-derivatives: new direction for stem cell therapy in human heart diseases. Circ Res. 2017;120:407–17.
Article CAS PubMed PubMed Central Google Scholar
Zihni C, Mills C, Matter K, Balda MS. Tight junctions: from simple barriers to multifunctional molecular gates. Nat Rev Mol
留言 (0)