aDepartment of Drug Development and Innovation (D3i), Institut Curie, Paris, France

bDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy

cINSERM U900 Research Unit, Saint-Cloud

dParis-Saclay University, Paris, France

Correspondence to Prof. Christophe Le Tourneau, MD, PhD, Department of Drug Development and Innovation (D3I), Institut Curie, 26 rue D’Ulm, 75248 Paris, France. Tel: + 33 (0)1 44 32 40 86; e-mail: [email protected]