Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer statistics 2020: GLOBOCAN estimates of incidence and Mortality Worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49.

Article  PubMed  Google Scholar 

Zhang L, Tang M, Chen S, Lei X, Zhang X, Huan Y. A meta-analysis of use of prostate imaging reporting and Data System Version 2 (PI-RADS V2) with multiparametric MR imaging for the detection of prostate cancer. Eur Radiol. 2017;27(12):5204–14.

Article  PubMed  Google Scholar 

Woo S, Suh CH, Kim SY, Cho JY, Kim SH. Diagnostic performance of prostate imaging reporting and Data System Version 2 for detection of prostate Cancer: a systematic review and diagnostic Meta-analysis. Eur Urol. 2017;72(2):177–88.

Article  PubMed  Google Scholar 

Ahmed HU, El-Shater Bosaily A, Brown LC, Gabe R, Kaplan R, Parmar MK, et al. Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study. Lancet Lond Engl. 2017;389(10071):815–22.

Article  Google Scholar 

Mottet N, van den Bergh RCN, Briers E, Van den Broeck T, Cumberbatch MG, De Santis M, et al. EAU-EANM-ESTRO-ESUR-SIOG guidelines on prostate Cancer—2020 update. Part 1: screening, diagnosis, and local treatment with curative intent. Eur Urol. 2021;79(2):243–62.

Article  CAS  PubMed  Google Scholar 

Apfelbeck M, Pfitzinger P, Bischoff R, Rath L, Buchner A, Mumm JN, et al. Predictive clinical features for negative histopathology of MRI/Ultrasound-fusion-guided prostate biopsy in patients with high likelihood of cancer at prostate MRI: analysis from a urologic outpatient clinic1. Clin Hemorheol Microcirc. 2021;76(4):503–11.

Article  Google Scholar 

Wajswol E, Winoker JS, Anastos H, Falagario U, Okhawere K, Martini A, et al. A cohort of transperineal electromagnetically tracked magnetic resonance imaging/ultrasonography fusion-guided biopsy: assessing the impact of inter-reader variability on cancer detection. BJU Int. 2020;125(4):531–40.

Article  CAS  PubMed  Google Scholar 

Sheridan AD, Nath SK, Aneja S, Syed JS, Pahade J, Mathur M, et al. MRI-Ultrasound Fusion targeted biopsy of prostate imaging reporting and Data System Version 2 category 5 lesions found false-positive at multiparametric prostate MRI. Am J Roentgenol. 2018;210(5):W218–25.

Article  Google Scholar 

Drobish JN, Bevill MD, Tracy CR, Sexton SM, Rajput M, Metz CM, et al. Do patients with a PI-RADS 5 lesion identified on magnetic resonance imaging require systematic biopsy in addition to targeted biopsy? Urol Oncol Semin Orig Investig. 2021;39(4):e2351–4.

Pepe P, Pennisi M. Negative Biopsy histology in men with PI-RADS score 5 in Daily Clinical Practice: incidence of Granulomatous Prostatitis. Clin Genitourin Cancer. 2020;18(6):e684–7.

Article  PubMed  Google Scholar 

Stavrinides V, Syer T, Hu Y, Giganti F, Freeman A, Karapanagiotis S, et al. False Positive Multiparametric Magnetic Resonance Imaging Phenotypes in the Biopsy-naïve prostate: are they distinct from significant Cancer-associated lesions? Lessons from PROMIS. Eur Urol. 2021;79(1):20–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Polanec SH, Helbich TH, Bickel H, Wengert GJ, Pinker K, Spick C, et al. Quantitative apparent diffusion coefficient derived from diffusion-weighted imaging has the potential to avoid unnecessary MRI-Guided biopsies of mpMRI-Detected PI-RADS 4 and 5 lesions. Invest Radiol. 2018;53(12):736–41.

Article  PubMed  Google Scholar 

Zhang Q, Wang W, Zhang B, Shi J, Fu Y, Li D, et al. Comparison of free-hand transperineal mpMRI/TRUS fusion-guided biopsy with transperineal 12-core systematic biopsy for the diagnosis of prostate cancer: a single-center prospective study in China. Int Urol Nephrol. 2017;49(3):439–48.

Article  PubMed  Google Scholar 

Weinreb JC, Barentsz JO, Choyke PL, Cornud F, Haider MA, Macura KJ, et al. Eur Urol. 2016;69(1):16–40. PI-RADS Prostate Imaging - Reporting and Data System: 2015, Version 2.

Marra G, Zhuang J, Beltrami M, Calleris G, Zhao X, Marquis A, et al. Transperineal freehand multiparametric MRI fusion targeted biopsies under local anaesthesia for prostate cancer diagnosis: a multicentre prospective study of 1014 cases. BJU Int. 2021;127(1):122–30.

Article  CAS  PubMed  Google Scholar 

Epstein JI, Egevad L, Amin MB, Delahunt B, Srigley JR, Humphrey PA et al. The 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma: Definition of Grading Patterns and Proposal for a New Grading System. Am J Surg Pathol. 2016;40(2):244–52.

Fütterer JJ, Briganti A, De Visschere P, Emberton M, Giannarini G, Kirkham A, et al. Can clinically significant prostate Cancer be detected with Multiparametric Magnetic Resonance Imaging? A systematic review of the literature. Eur Urol. 2015;68(6):1045–53.

Article  PubMed  Google Scholar 

Otti VC, Miller C, Powell RJ, Thomas RM, McGrath JS. The diagnostic accuracy of multiparametric magnetic resonance imaging before biopsy in the detection of prostate cancer. BJU Int. 2019;123(1):82–90.

Article  PubMed  Google Scholar 

Soeterik TFW, van Melick HHE, Dijksman LM, Küsters-Vandevelde H, Stomps S, Schoots IG et al. Development and External Validation of a Novel Nomogram to predict side-specific extraprostatic extension in patients with prostate Cancer undergoing radical prostatectomy. Eur Urol Oncol. 2020;S2588-9311(20)30133-4.

Shoji S, Hiraiwa S, Hanada I, Kim H, Nitta M, Hasegawa M, et al. Current status and future prospective of focal therapy for localized prostate cancer: development of multiparametric MRI, MRI-TRUS fusion image-guided biopsy, and treatment modalities. Int J Clin Oncol. 2020;25(4):509–20.

Article  PubMed  Google Scholar 

May EJ, Viers LD, Viers BR, Kawashima A, Kwon ED, Karnes RJ, et al. Prostate cancer post-treatment follow-up and recurrence evaluation. Abdom Radiol N Y. 2016;41(5):862–76.

Article  Google Scholar 

Kitzing YX, Prando A, Varol C, Karczmar GS, Maclean F, Oto A. Benign conditions that mimic prostate carcinoma: MR Imaging Features with histopathologic correlation. Radiographics. 2016;36(1):162–75.

Article  PubMed  Google Scholar 

Davenport MS, Downs E, George AK, Curci NE, Salka BR, Sullivan TQ, et al. Prostate imaging and data reporting System Version 2 as a Radiology Performance Metric: an analysis of 18 abdominal radiologists. J Am Coll Radiol JACR. 2021;18(8):1069–76.

Article  PubMed  Google Scholar 

Falagario UG, Jambor I, Lantz A, Ettala O, Stabile A, Taimen P, et al. Combined use of prostate-specific Antigen Density and Magnetic Resonance Imaging for prostate biopsy decision planning: a retrospective multi-institutional study using the prostate magnetic resonance imaging outcome database (PROMOD). Eur Urol Oncol. 2021;4(6):971–9.

Article  PubMed  Google Scholar 

Lee SM, Wolfe K, Acher P, Liyanage SH. Multiparametric MRI appearances of primary granulomatous prostatitis. Br J Radiol. 2019;92(1098):20180075.

Article  PubMed  PubMed Central  Google Scholar 

Shakur A, Hames K, O’Shea A, Harisinghani MG. Prostatitis: imaging appearances and diagnostic considerations. Clin Radiol. 2021;76(6):416–26.

Article  CAS  PubMed  Google Scholar 

Bruno SM, Falagario UG, d’Altilia N, Recchia M, Mancini V, Selvaggio O, et al. PSA Density help to identify patients with elevated PSA due to prostate Cancer Rather Than Intraprostatic inflammation: a prospective single Center Study. Front Oncol. 2021;11:693684.

Article  PubMed  PubMed Central  Google Scholar