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DZSM improves cognition by facilitating LTP.
•DZSM regulates the NMDA receptor-mediated Ca2+/CaMKII pathway.
•Flavonoids and caffeoyl compounds are active components of DZSM.
•Scu is promising to treat cognitive deficits.
© 2023 The Author(s). Published by Elsevier B.V. on behalf of Xi’an Jiaotong University.
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