Funding

Kazumasa Komura was partially supported by Grant-in-Aid No. 21H03070 (Japan Society for the Promotion of Science: JSPS), the Kenzo Suzuki Memorial Foundation, the SGH Foundation, the Naito Memorial Foundation, and the Cancer Translational Research Foundation of Japanese Urological Association (JUA).

Conflict of Interest

Taizo Uchimoto, Shuya Tsuchida, Kazumasa Komura, Wataru Fukuokaya, Takahiro Adachi, Yosuke Hirasawa, Takeshi Hashimoto, Atsuhiko Yoshizawa, Masanobu Saruta, Mamoru Hashimoto, Takuya Higashio, Takuya Matsuda, Kazuki Nishimura, Takuya Tsujino, Ko Nakamura, Tatsuo Fukushima, Kyosuke Nishio, Shutaro Yamamoto, Kosuke Iwatani, Fumihiko Urabe, Keiichiro Mori, Takafumi Yanagisawa, Shunsuke Tsuduki, Kiyoshi Takahara, Teruo Inamoto, Jun Miki, Kazutoshi Fujita, Takahiro Kimura, Yoshio Ohno, Ryoichi Shiroki, Hirotsugu Uemura, and Haruhito Azuma declare that they have no conflicts of interest that might be relevant to the contents of this manuscript.

Ethics Approval

This study was approved by the Institutional Review Board (IRB) from Osaka Medical and Pharmaceutical University (approval number: RIN-750-2571, approved on 24th January 2020). This observational study adhered to ethical principles aligned with the Declaration of Helsinki, the International Conference on Harmonisation’s Good Clinical Practice guidelines, Good Pharmacoepidemiology Practices, and relevant laws for noninterventional and observational studies.

Consent to Participate

Not applicable.

Consent to Publish

Not applicable.

Data Availability

The data from this study can be accessed by academic and commercial partners upon a reasonable request, subject to IRB approval and a data use agreement. For further details or to reanalyze the study’s data, contact the Lead Contact at kazumasa.komura@ompu.ac.jp.

Code Availability

Not applicable.

Author Contributions

T. Uchimoto: conceptualization, data curation, analysis, investigation, methodology, software, visualization, writing original draft, supervision. S. Tsuchida: data curation, analysis, investigation, methodology, software, visualization. K. Komura: data curation, investigation, investigation, writing the original draft, supervision. W. Fukuokaya: investigation, data curation, validation. A. Adachi: validation, methodology. Y. Hirasawa: methodology, validation. T. Hashimoto: methodology, validation. A. Yoshizawa: data curation. M. Saruta: data curation. M. Hashimoto: analysis. T. Higashio: data curation, analysis. T. Matsuda: investigation. K. Nishimura: data curation. T. Tsujino: methodology, data curation. K. Nakamura: investigation. T. Fukushima: data curation, analysis. K. Nishio: validation. S. Yamamoto: data curation. K. Iwatani: investigation, supervision. F. Urabe: investigation, validation, supervision. K. Mori: methodology, data analysis. T. Yanagisawa: investigation. S. Tsuduki: writing original draft, review. K, Takahara: editing, supervision. T. Inamoto: data curation. J. Miki: data curation, analysis. K. Fujita: review and editing, supervision. T. Kimura: investigation, validation, supervision. Y. Ohno: supervision. R. Shiroki: supervision. H. Uemura: supervision. H. Azuma: supervision.