1Genomics Research Center, Academia Sinica, Taipei, Taiwan;

2Chang Gung Memorial Hospital, Linkou Branch, Taoyuan City, Taiwan;

3Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan City, Taiwan;

4Chang Gung University College of Medicine, Taoyuan City, Taiwan;

5Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Hsinchu, Taiwan;

6Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan;

7Biomedical Translation Research Center, Academia Sinica, Taipei, Taiwan.

Correspondence: Hwai-I Yang, PhD. E-mail: [email protected].

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