Recent research advances in pain mechanisms in McCune–Albright syndrome thinking about the pain mechanism of FD/MAS

Tucker-Bartley A, Selen DJ, Golden E, van Gool R, Ebb D, Mannstadt M, Upadhyay J. Pharmacological interventions targeting pain in fibrous dysplasia/McCune-Albright syndrome. Int J Mol Sci. 2023;24(3):2550. https://doi.org/10.3390/ijms24032550.PMID:36768871;PMCID:PMC9916440.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zeng BH. Current status of diagnosis and treatment of McCune-Albright syndrome. Med Rev. 2016;22(22):4475–9.

Google Scholar 

Jiang X, Li Y. Advances in the study of McCune-Albright syndrome in children. Chin J Pediatr Surg. 2015;36(12):956–60.

Google Scholar 

Golden E, Zhang F, Selen DJ, Ebb D, Romo L, Drubach LA, Shah N, O’Donnell LJ, Lemme JD, Myers R, Cay M, Kronenberg HM, Westin CF, Boyce AM, Kaban LB, Upadhyay J. Case report: the imperfect association between craniofacial lesion burden and pain in fibrous dysplasia. Front Neurol. 2022;16(13): 855157. https://doi.org/10.3389/fneur.2022.855157.PMID:35370900;PMCID:PMC8966612.

Article  Google Scholar 

Chapurlat RD, Gensburger D, Jimenez-Andrade JM, Ghilardi JR, Kelly M, Mantyh P. Pathophysiology and medical treatment of pain in fibrous dysplasia of bone. Orphanet J Rare Dis. 2012;7(Suppl 1):S3. https://doi.org/10.1186/1750-1172-7-S1-S3.

Article  PubMed  PubMed Central  Google Scholar 

Hendrickx G, Fischer V, Liedert A, von Kroge S, Haffner-Luntzer M, Brylka L, Pawlus E, Schweizer M, Yorgan T, Baranowsky A, Rolvien T, Neven M, Schumacher U, Beech DJ, Amling M, Ignatius A, Schinke T. Piezo1 inactivation in chondrocytes impairs trabecular bone formation. J Bone Miner Res. 2021;36(2):369–84. https://doi.org/10.1002/jbmr.4198. (Epub 2020 Nov 12 PMID: 33180356).

Article  CAS  PubMed  Google Scholar 

Wang L, You X, Lotinun S, Zhang L, Wu N, Zou W. Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk. Nat Commun. 2020;11(1):282. https://doi.org/10.1038/s41467-019-14146-6.PMID:31941964;PMCID:PMC6962448.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sasaki F, Hayashi M, Mouri Y, Nakamura S, Adachi T, Nakashima T. Mechanotransduction via the Piezo1-Akt pathway underlies Sost suppression in osteocytes. Biochem Biophys Res Commun. 2020;521(3):806–13. https://doi.org/10.1016/j.bbrc.2019.10.174. (Epub 2019 Nov 8 PMID: 31708103).

Article  CAS  PubMed  Google Scholar 

Sonkodi B. Miswired proprioception in amyotrophic lateral sclerosis in relation to pain sensation (and in delayed onset muscle soreness)-Is Piezo2 channelopathy a principal transcription activator in proprioceptive terminals besides being the potential primary damage? Life. 2023;13(3):657. https://doi.org/10.3390/life13030657.PMID:36983813;PMCID:PMC10053310.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Szczot M, Liljencrantz J, Ghitani N, Barik A, Lam R, Thompson JH, Bharucha-Goebel D, Saade D, Necaise A, Donkervoort S, Foley AR, Gordon T, Case L, Bushnell MC, Bönnemann CG, Chesler AT. PIEZO2 mediates injury-induced tactile pain in mice and humans. Sci Transl Med. 2018;10(462):9892. https://doi.org/10.1126/scitranslmed.aat9892.

Article  CAS  Google Scholar 

Nagy ZF, Sonkodi B, Pál M, Klivényi P, Széll M. Likely pathogenic variants of Cav1. 3 and Nav1. 1 encoding genes in amyotrophic lateral sclerosis could elucidate the dysregulated pain pathways. Biomedicines. 2023;11(3):933. https://doi.org/10.3390/biomedicines11030933.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Venugopal S, Ghulam-Jhelani Z, Ahn IS, Yang X, Wiedau M, Simmons D, Chandler SH. Early deficits in GABA inhibition parallels an increase in L-type Ca2+ currents in the jaw motor neurons of SOD1G93A mouse model for ALS. Neurobiol Dis. 2023;177: 105992. https://doi.org/10.1016/j.nbd.2023.105992. (Epub 2023 Jan 6 PMID: 36623607).

Article  CAS  PubMed  Google Scholar 

Perin M, Chinigò G, Genova T, Mussano F, Munaron L. The impact of plasma membrane ion channels on bone remodeling in response to mechanical stress, oxidative imbalance, and acidosis. Antioxidants. 2023;12(3):689. https://doi.org/10.3390/antiox12030689.PMID:36978936;PMCID:PMC10045377.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Agidigbi TS, Kim C. Reactive oxygen species in osteoclast differentiation and possible pharmaceutical targets of ROS-mediated osteoclast diseases. Int J Mol Sci. 2019;20(14):3576. https://doi.org/10.3390/ijms20143576.PMID:31336616;PMCID:PMC6678498.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dizin E, Olivier V, Roth I, Sassi A, Arnoux G, Ramakrishnan S, Morel S, Kwak BR, Loffing J, Hummler E, Wenger RH, Frew IJ, Feraille E. Activation of the hypoxia-inducible factor pathway inhibits epithelial sodium channel-mediated sodium transport in collecting duct principal cells. J Am Soc Nephrol. 2021;32(12):3130–45. https://doi.org/10.1681/ASN.2021010046.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Boyce AM, Kelly MH, Brillante BA, Kushner H, Wientroub S, Riminucci M, Bianco P, Robey PG, Collins MT. A randomized, double blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone. J Clin Endocrinol Metab. 2014;99(11):4133–40. https://doi.org/10.1210/jc.2014-1371.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhen G, Fu Y, Zhang C, Ford NC, Wu X, Wu Q, Yan D, Chen X, Cao X, Guan Y. Mechanisms of bone pain: progress in research from bench to bedside. Bone Res. 2022;10(1):44. https://doi.org/10.1038/s41413-022-00217-w.PMID:35668080;PMCID:PMC9170780.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Koivisto AP, Belvisi MG, Gaudet R, Szallasi A. Advances in TRP channel drug discovery: from target validation to clinical studies. Nat Rev Drug Discov. 2022;21(1):41–59. https://doi.org/10.1038/s41573-021-00268-4.

Article  CAS  PubMed  Google Scholar 

Duitama M, Vargas-López V, Casas Z, Albarracin SL, Sutachan JJ, Torres YP. TRP channels role in pain associated with neurodegenerative diseases. Front Neurosci. 2020;4(14):782. https://doi.org/10.3389/fnins.2020.00782.PMID:32848557;PMCID:PMC7417429.

Article  Google Scholar 

Liu YS, Liu YA, Huang CJ, Yen MH, Tseng CT, Chien S, Lee OK. Mechanosensitive TRPM7 mediates shear stress and modulates osteogenic differentiation of mesenchymal stromal cells through osterix pathway. Sci Rep. 2015;12(5):16522. https://doi.org/10.1038/srep16522.PMID:26558702;PMCID:PMC4642269.

Article  Google Scholar 

Son A, Kang N, Kang JY, Kim KW, Yang YM, Shin DM. TRPM3/TRPV4 regulates Ca2+-mediated RANKL/NFATc1 expression in osteoblasts. J Mol Endocrinol. 2018;61(4):207–18. https://doi.org/10.1530/JME-18-0051. (PMID: 30328352).

Article  CAS  PubMed  Google Scholar 

Corrigan MA, Johnson GP, Stavenschi E, Riffault M, Labour MN, Hoey DA. TRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium. Sci Rep. 2018;8(1):3824. https://doi.org/10.1038/s41598-018-22174-3.PMID:29491434;PMCID:PMC5830574.

Article  PubMed  PubMed Central  Google Scholar 

Du G, Chen W, Li L, Zhang Q. The potential role of mechanosensitive ion channels in substrate stiffness-regulated Ca2+ response in chondrocytes. Connect Tissue Res. 2022;63(5):453–62. https://doi.org/10.1080/03008207.2021.2007902. (Epub 2021 Nov 23 PMID: 34814790).

Article  CAS  PubMed  Google Scholar 

Dutta B, Arya RK, Goswami R, Alharbi MO, Sharma S, Rahaman SO. Role of macrophage TRPV4 in inflammation. Lab Invest. 2020;100(2):178–85. https://doi.org/10.1038/s41374-019-0334-6.

Article  CAS  PubMed  Google Scholar 

Liu BL, Cao QL, Zhao X, Liu HZ, Zhang YQ. Inhibition of TRPV1 by SHP-1 in nociceptive primary sensory neurons is critical in PD-L1 analgesia. JCI Insight. 2020;5(20): e137386. https://doi.org/10.1172/jci.insight.137386.PMID:32960817;PMCID:PMC7605531.

Article  PubMed  PubMed Central  Google Scholar 

Chen W, Li H, Hao X, Liu C. TRPV1 in dorsal root ganglion contributed to bone cancer pain. Front Pain Res. 2022;9(3):1022022. https://doi.org/10.3389/fpain.2022.1022022.PMID:36438444;PMCID:PMC9682177.

Article  Google Scholar 

Wein MN, Kronenberg HM. Regulation of bone remodeling by parathyroid hormone. Cold Spring Harb Perspect Med. 2018;8(8): a031237. https://doi.org/10.1101/cshperspect.a031237.PMID:29358318;PMCID:PMC6071549.

Article  PubMed  PubMed Central  Google Scholar 

Du L, Feng R, Ge S. PTH/SDF-1α cotherapy promotes proliferation, migration and osteogenic differentiation of human periodontal ligament stem cells. Cell Prolif. 2016;49(5):599–608. https://doi.org/10.1111/cpr.12286.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tamma R, Colaianni G, Zhu LL, DiBenedetto A, Greco G, Montemurro G, Patano N, Strippoli M, Vergari R, Mancini L, Colucci S, Grano M, Faccio R, Liu X, Li J, Usmani S, Bachar M, Bab I, Nishimori K, Young LJ, Buettner C, Iqbal J, Sun L, Zaidi M, Zallone A. Oxytocin is an anabolic bone hormone. Proc Natl Acad Sci USA. 2009;106(17):7149–54. https://doi.org/10.1073/pnas.0901890106.

Article  PubMed  PubMed Central  Google Scholar 

Klein GL. Insulin and bone: recent developments. World J Diabetes. 2014;5(1):14–6. https://doi.org/10.4239/wjd.v5.i1.14.PMID:24567798;PMCID:PMC3932424.

Article  PubMed  PubMed Central  Google Scholar 

Jackson E, Lara-Castillo N, Akhter MP, Dallas M, Scott JM, Ganesh T, Johnson ML. Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice. Bone Rep. 2021;14(15): 101129. https://doi.org/10.1016/j.bonr.2021.101129.PMID:34584905;PMCID:PMC8455641.

留言 (0)

沒有登入
gif