Tucker-Bartley A, Selen DJ, Golden E, van Gool R, Ebb D, Mannstadt M, Upadhyay J. Pharmacological interventions targeting pain in fibrous dysplasia/McCune-Albright syndrome. Int J Mol Sci. 2023;24(3):2550. https://doi.org/10.3390/ijms24032550.PMID:36768871;PMCID:PMC9916440.
Article CAS PubMed PubMed Central Google Scholar
Zeng BH. Current status of diagnosis and treatment of McCune-Albright syndrome. Med Rev. 2016;22(22):4475–9.
Jiang X, Li Y. Advances in the study of McCune-Albright syndrome in children. Chin J Pediatr Surg. 2015;36(12):956–60.
Golden E, Zhang F, Selen DJ, Ebb D, Romo L, Drubach LA, Shah N, O’Donnell LJ, Lemme JD, Myers R, Cay M, Kronenberg HM, Westin CF, Boyce AM, Kaban LB, Upadhyay J. Case report: the imperfect association between craniofacial lesion burden and pain in fibrous dysplasia. Front Neurol. 2022;16(13): 855157. https://doi.org/10.3389/fneur.2022.855157.PMID:35370900;PMCID:PMC8966612.
Chapurlat RD, Gensburger D, Jimenez-Andrade JM, Ghilardi JR, Kelly M, Mantyh P. Pathophysiology and medical treatment of pain in fibrous dysplasia of bone. Orphanet J Rare Dis. 2012;7(Suppl 1):S3. https://doi.org/10.1186/1750-1172-7-S1-S3.
Article PubMed PubMed Central Google Scholar
Hendrickx G, Fischer V, Liedert A, von Kroge S, Haffner-Luntzer M, Brylka L, Pawlus E, Schweizer M, Yorgan T, Baranowsky A, Rolvien T, Neven M, Schumacher U, Beech DJ, Amling M, Ignatius A, Schinke T. Piezo1 inactivation in chondrocytes impairs trabecular bone formation. J Bone Miner Res. 2021;36(2):369–84. https://doi.org/10.1002/jbmr.4198. (Epub 2020 Nov 12 PMID: 33180356).
Article CAS PubMed Google Scholar
Wang L, You X, Lotinun S, Zhang L, Wu N, Zou W. Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk. Nat Commun. 2020;11(1):282. https://doi.org/10.1038/s41467-019-14146-6.PMID:31941964;PMCID:PMC6962448.
Article CAS PubMed PubMed Central Google Scholar
Sasaki F, Hayashi M, Mouri Y, Nakamura S, Adachi T, Nakashima T. Mechanotransduction via the Piezo1-Akt pathway underlies Sost suppression in osteocytes. Biochem Biophys Res Commun. 2020;521(3):806–13. https://doi.org/10.1016/j.bbrc.2019.10.174. (Epub 2019 Nov 8 PMID: 31708103).
Article CAS PubMed Google Scholar
Sonkodi B. Miswired proprioception in amyotrophic lateral sclerosis in relation to pain sensation (and in delayed onset muscle soreness)-Is Piezo2 channelopathy a principal transcription activator in proprioceptive terminals besides being the potential primary damage? Life. 2023;13(3):657. https://doi.org/10.3390/life13030657.PMID:36983813;PMCID:PMC10053310.
Article CAS PubMed PubMed Central Google Scholar
Szczot M, Liljencrantz J, Ghitani N, Barik A, Lam R, Thompson JH, Bharucha-Goebel D, Saade D, Necaise A, Donkervoort S, Foley AR, Gordon T, Case L, Bushnell MC, Bönnemann CG, Chesler AT. PIEZO2 mediates injury-induced tactile pain in mice and humans. Sci Transl Med. 2018;10(462):9892. https://doi.org/10.1126/scitranslmed.aat9892.
Nagy ZF, Sonkodi B, Pál M, Klivényi P, Széll M. Likely pathogenic variants of Cav1. 3 and Nav1. 1 encoding genes in amyotrophic lateral sclerosis could elucidate the dysregulated pain pathways. Biomedicines. 2023;11(3):933. https://doi.org/10.3390/biomedicines11030933.
Article CAS PubMed PubMed Central Google Scholar
Venugopal S, Ghulam-Jhelani Z, Ahn IS, Yang X, Wiedau M, Simmons D, Chandler SH. Early deficits in GABA inhibition parallels an increase in L-type Ca2+ currents in the jaw motor neurons of SOD1G93A mouse model for ALS. Neurobiol Dis. 2023;177: 105992. https://doi.org/10.1016/j.nbd.2023.105992. (Epub 2023 Jan 6 PMID: 36623607).
Article CAS PubMed Google Scholar
Perin M, Chinigò G, Genova T, Mussano F, Munaron L. The impact of plasma membrane ion channels on bone remodeling in response to mechanical stress, oxidative imbalance, and acidosis. Antioxidants. 2023;12(3):689. https://doi.org/10.3390/antiox12030689.PMID:36978936;PMCID:PMC10045377.
Article CAS PubMed PubMed Central Google Scholar
Agidigbi TS, Kim C. Reactive oxygen species in osteoclast differentiation and possible pharmaceutical targets of ROS-mediated osteoclast diseases. Int J Mol Sci. 2019;20(14):3576. https://doi.org/10.3390/ijms20143576.PMID:31336616;PMCID:PMC6678498.
Article CAS PubMed PubMed Central Google Scholar
Dizin E, Olivier V, Roth I, Sassi A, Arnoux G, Ramakrishnan S, Morel S, Kwak BR, Loffing J, Hummler E, Wenger RH, Frew IJ, Feraille E. Activation of the hypoxia-inducible factor pathway inhibits epithelial sodium channel-mediated sodium transport in collecting duct principal cells. J Am Soc Nephrol. 2021;32(12):3130–45. https://doi.org/10.1681/ASN.2021010046.
Article CAS PubMed PubMed Central Google Scholar
Boyce AM, Kelly MH, Brillante BA, Kushner H, Wientroub S, Riminucci M, Bianco P, Robey PG, Collins MT. A randomized, double blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone. J Clin Endocrinol Metab. 2014;99(11):4133–40. https://doi.org/10.1210/jc.2014-1371.
Article CAS PubMed PubMed Central Google Scholar
Zhen G, Fu Y, Zhang C, Ford NC, Wu X, Wu Q, Yan D, Chen X, Cao X, Guan Y. Mechanisms of bone pain: progress in research from bench to bedside. Bone Res. 2022;10(1):44. https://doi.org/10.1038/s41413-022-00217-w.PMID:35668080;PMCID:PMC9170780.
Article CAS PubMed PubMed Central Google Scholar
Koivisto AP, Belvisi MG, Gaudet R, Szallasi A. Advances in TRP channel drug discovery: from target validation to clinical studies. Nat Rev Drug Discov. 2022;21(1):41–59. https://doi.org/10.1038/s41573-021-00268-4.
Article CAS PubMed Google Scholar
Duitama M, Vargas-López V, Casas Z, Albarracin SL, Sutachan JJ, Torres YP. TRP channels role in pain associated with neurodegenerative diseases. Front Neurosci. 2020;4(14):782. https://doi.org/10.3389/fnins.2020.00782.PMID:32848557;PMCID:PMC7417429.
Liu YS, Liu YA, Huang CJ, Yen MH, Tseng CT, Chien S, Lee OK. Mechanosensitive TRPM7 mediates shear stress and modulates osteogenic differentiation of mesenchymal stromal cells through osterix pathway. Sci Rep. 2015;12(5):16522. https://doi.org/10.1038/srep16522.PMID:26558702;PMCID:PMC4642269.
Son A, Kang N, Kang JY, Kim KW, Yang YM, Shin DM. TRPM3/TRPV4 regulates Ca2+-mediated RANKL/NFATc1 expression in osteoblasts. J Mol Endocrinol. 2018;61(4):207–18. https://doi.org/10.1530/JME-18-0051. (PMID: 30328352).
Article CAS PubMed Google Scholar
Corrigan MA, Johnson GP, Stavenschi E, Riffault M, Labour MN, Hoey DA. TRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium. Sci Rep. 2018;8(1):3824. https://doi.org/10.1038/s41598-018-22174-3.PMID:29491434;PMCID:PMC5830574.
Article PubMed PubMed Central Google Scholar
Du G, Chen W, Li L, Zhang Q. The potential role of mechanosensitive ion channels in substrate stiffness-regulated Ca2+ response in chondrocytes. Connect Tissue Res. 2022;63(5):453–62. https://doi.org/10.1080/03008207.2021.2007902. (Epub 2021 Nov 23 PMID: 34814790).
Article CAS PubMed Google Scholar
Dutta B, Arya RK, Goswami R, Alharbi MO, Sharma S, Rahaman SO. Role of macrophage TRPV4 in inflammation. Lab Invest. 2020;100(2):178–85. https://doi.org/10.1038/s41374-019-0334-6.
Article CAS PubMed Google Scholar
Liu BL, Cao QL, Zhao X, Liu HZ, Zhang YQ. Inhibition of TRPV1 by SHP-1 in nociceptive primary sensory neurons is critical in PD-L1 analgesia. JCI Insight. 2020;5(20): e137386. https://doi.org/10.1172/jci.insight.137386.PMID:32960817;PMCID:PMC7605531.
Article PubMed PubMed Central Google Scholar
Chen W, Li H, Hao X, Liu C. TRPV1 in dorsal root ganglion contributed to bone cancer pain. Front Pain Res. 2022;9(3):1022022. https://doi.org/10.3389/fpain.2022.1022022.PMID:36438444;PMCID:PMC9682177.
Wein MN, Kronenberg HM. Regulation of bone remodeling by parathyroid hormone. Cold Spring Harb Perspect Med. 2018;8(8): a031237. https://doi.org/10.1101/cshperspect.a031237.PMID:29358318;PMCID:PMC6071549.
Article PubMed PubMed Central Google Scholar
Du L, Feng R, Ge S. PTH/SDF-1α cotherapy promotes proliferation, migration and osteogenic differentiation of human periodontal ligament stem cells. Cell Prolif. 2016;49(5):599–608. https://doi.org/10.1111/cpr.12286.
Article CAS PubMed PubMed Central Google Scholar
Tamma R, Colaianni G, Zhu LL, DiBenedetto A, Greco G, Montemurro G, Patano N, Strippoli M, Vergari R, Mancini L, Colucci S, Grano M, Faccio R, Liu X, Li J, Usmani S, Bachar M, Bab I, Nishimori K, Young LJ, Buettner C, Iqbal J, Sun L, Zaidi M, Zallone A. Oxytocin is an anabolic bone hormone. Proc Natl Acad Sci USA. 2009;106(17):7149–54. https://doi.org/10.1073/pnas.0901890106.
Article PubMed PubMed Central Google Scholar
Klein GL. Insulin and bone: recent developments. World J Diabetes. 2014;5(1):14–6. https://doi.org/10.4239/wjd.v5.i1.14.PMID:24567798;PMCID:PMC3932424.
Article PubMed PubMed Central Google Scholar
Jackson E, Lara-Castillo N, Akhter MP, Dallas M, Scott JM, Ganesh T, Johnson ML. Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice. Bone Rep. 2021;14(15): 101129. https://doi.org/10.1016/j.bonr.2021.101129.PMID:34584905;PMCID:PMC8455641.
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