Cross AS, Hyun SW, Miranda-Ribera A, Feng C, Liu A, Nguyen C, et al. NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not. J Biol Chem. 2012;287(19):15966–80.
Article CAS PubMed PubMed Central Google Scholar
Lillehoj EP, Hyun SW, Feng C, Zhang L, Liu A, Guang W, et al. NEU1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signaling. J Biol Chem. 2012;287(11):8214–31.
Article CAS PubMed PubMed Central Google Scholar
Katoh S, Maeda S, Fukuoka H, Wada T, Moriya S, Mori A, et al. A crucial role of sialidase Neu1 in hyaluronan receptor function of CD44 in T helper type 2-mediated airway inflammation of murine acute asthmatic model. Clin Exp Immunol. 2010;161(2):233–4.
Article CAS PubMed PubMed Central Google Scholar
Katoh S. Critical involvement of CD44 in T helper type 2 cell-mediated eosinophilic airway inflammation in a mouse model of acute asthma. Front Immunol. 2022;12:811600.
Article PubMed PubMed Central Google Scholar
Luzina IG, Lockatell V, Hyun SW, Kopach P, Kang PH, Noor Z, et al. Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis. Am J Physiol Lung Cell Mol Physiol. 2016;310(10):L940–54.
Article PubMed PubMed Central Google Scholar
Luzina IG, Lillehoj EP, Lockatell V, Hyun SW, Lugkey KN, Imamura A, et al. Therapeutic effect of neuraminidase-1-selective inhibition in mouse models of bleomycin-induced pulmonary inflammation and fibrosis. J Pharmacol Exp Ther. 2021;376(1):136–46.
Article PubMed PubMed Central Google Scholar
Karhadkar TR, Meek TD, Gomer RH. Inhibiting sialidase-induced TGF-β1 activation attenuates pulmonary fibrosis in mice. J Pharmacol Exp Ther. 2021;376(1):106–17.
Article CAS PubMed PubMed Central Google Scholar
Lillehoj EP, Hyun SW, Liu A, Guang W, Verceles AC, Luzina IG, et al. NEU1 sialidase regulates membrane-tethered mucin (MUC1) ectodomain adhesiveness for Pseudomonas aeruginosa and decoy receptor release. J Biol Chem. 2015;290(30):18316–31.
Article CAS PubMed PubMed Central Google Scholar
Lillehoj EP, Guang W, Hyun SW, Liu A, Hegerle N, Simon R, et al. Neuraminidase 1-mediated desialylation of the mucin 1 ectodomain releases a decoy receptor that protects against Pseudomonas aeruginosa lung infection. J Biol Chem. 2019;294(2):662–78.
Article CAS PubMed Google Scholar
Verceles AC, Bhat P, Nagaria Z, Martin D, Patel H, Ntem-Mensah A, et al. MUC1 ectodomain is a flagellin-targeting decoy receptor and biomarker operative during Pseudomonas aeruginosa lung infection. Sci Rep. 2021;11(1):22725.
Article CAS PubMed PubMed Central Google Scholar
Bonten EJ, Annunziata I, d’Azzo A. Lysosomal multienzyme complex: pros and cons of working together. Cell Mol Life Sci. 2014;71(11):2017–32.
Article CAS PubMed Google Scholar
Bennasroune A, Romier-Crouzet B, Blaise S, Laffargue M, Efremov RG, et al. Elastic fibers and elastin receptor complex: neuraminidase-1 takes the center stage. Matrix Biol. 2019;84:57–67.
Article CAS PubMed Google Scholar
Lee C, Liu A, Miranda-Ribera A, Hyun SW, Lillehoj EP, Cross AS, et al. NEU1 sialidase regulates the sialylation state of CD31 and disrupts CD31-driven capillary-like tube formation in human lung microvascular endothelia. J Biol Chem. 2014;289(13):9121–35.
Article CAS PubMed PubMed Central Google Scholar
Feng C, Zhang L, Nguyen C, Vogel SN, Goldblum SE, Blackwelder WC, et al. Neuraminidase reprograms lung tissue and potentiates lipopolysaccharide-induced acute lung injury in mice. J Immunol. 2013;191(9):4828–37.
Article CAS PubMed Google Scholar
Singh V, Ulasov I, Gupta S, Singh A, Roy VK, Kharwar RK. Idiopathic pulmonary fibrosis: where do we stand and how far to go? Discov Med. 2024;36(180):22.
Mutsaers SE, Miles T, Prêle CM, Hoyne GF. Emerging role of immune cells as drivers of pulmonary fibrosis. Pharmacol Ther. 2023;252:108562.
Article CAS PubMed Google Scholar
Jayanth P, Amith SR, Gee K, Szewczuk MR. Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for neurotrophin activation of Trk receptors and cellular signaling. Cell Signal. 2010;22(8):1193–205.
Article CAS PubMed Google Scholar
Hinek A, Bodnaruk TD, Bunda S, Wang Y, Liu K. Neuraminidase-1, a subunit of the cell surface elastin receptor, desialylates and functionally inactivates adjacent receptors interacting with the mitogenic growth factors PDGF-BB and IGF-2. Am J Pathol. 2008;173(4):1042–56.
Article CAS PubMed PubMed Central Google Scholar
Wu Y, Zhang J, Zheng JX. Angiogenesis and pulmonary fibrosis. Zhonghua Jie He He Hu Xi Za Zhi. 2023;46(2):197–202.
Pilling D, Sahlberg K, Chen W, Gomer RH. Changes in lung sialidases in male and female mice after bleomycin aspiration. Exp Lung Res. 2022;48(9–10):291–304.
Article CAS PubMed PubMed Central Google Scholar
Chen W, Karhadkar TR, Ryu C, Herzog EL, Gomer RH. Reduced sialylation and bioactivity of the antifibrotic protein serum amyloid P in the sera of patients with idiopathic pulmonary fibrosis. Immunohorizons. 2020;4(6):352–62.
Article CAS PubMed Google Scholar
Karhadkar TR, Chen W, Gomer RH. Attenuated pulmonary fibrosis in sialidase-3 knockout (Neu3−/−) mice. Am J Physiol Lung Cell Mol Physiol. 2020;318(1):L165–79.
Article CAS PubMed Google Scholar
Lloyd CM, Saglani S. T cells in asthma: influences of genetics, environment, and T-cell plasticity. J Allergy Clin Immunol. 2013;131(5):1267–74.
Article CAS PubMed Google Scholar
Chen GY, Brown NK, Wu W, Khedri Z, Yu H, Chen X, et al. Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1. Elife. 2014;3: e04066.
Article PubMed PubMed Central Google Scholar
Hewson CA, Jardine A, Edwards MR, Laza-Stanca V, Johnston SL. Toll-like receptor 3 is induced by and mediates antiviral activity against rhinovirus infection of human bronchial epithelial cells. J Virol. 2005;79(19):12273–9.
Article CAS PubMed PubMed Central Google Scholar
Pech M, Weckmann M, König IR, Franke A, Heinsen FA, Oliver B, et al. Rhinovirus infections change DNA methylation and mRNA expression in children with asthma. PLoS ONE. 2018;13(11): e0205275.
Article PubMed PubMed Central Google Scholar
Toussaint K, Appert-Collin A, Morjani H, Albrecht C, Sartelet H, Romier-Crouzet B, Maurice P, Duca L, Blaise S, Bennasroune A. Neuraminidase-1: a sialidase involved in the development of cancers and metabolic diseases. Cancers. 2022;14(19):4868.
Article CAS PubMed PubMed Central Google Scholar
Haxho F, Neufeld RJ, Szewczuk MR. Neuraminidase-1: a novel therapeutic target in multistage tumorigenesis. Oncotarget. 2016;7(26):40860–81.
Article PubMed PubMed Central Google Scholar
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49.
Yin X, Li Y, Wang H, Jia T, Wang E, Luo Y, et al. Small cell lung cancer transformation: from pathogenesis to treatment. Semin Cancer Biol. 2022;86(Pt 2):595–606.
Article CAS PubMed Google Scholar
Liu YC, Yen HY, Chen CY, Chen CH, Cheng PF, Juan YH, et al. Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells. Proc Natl Acad Sci USA. 2011;108(28):11332–7.
Article CAS PubMed PubMed Central Google Scholar
Uemura T, Shiozaki K, Yamaguchi K, Miyazaki S, Satomi S, Kato K, et al. Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer cells through desialylation of integrin beta4. Oncogene. 2009;28(9):1218–29.
Article CAS PubMed Google Scholar
Lv T, Lv H, Fei J, Xie Y, Lian D, Hu J, et al. p53–R273H promotes cancer cell migration via upregulation of neuraminidase-1. J Cancer. 2020;11(23):6874–82.
Article CAS PubMed PubMed Central Google Scholar
Efeoglu E, Henry M, Clynes M, Meleady P. Label-free quantitative proteomics analysis of adriamycin selected multidrug resistant human lung ca
留言 (0)