Chimeric Monkey Born Alive with a High Contribution of Donor Cells

Zheng C, Ballard EB, Wu J. The road to generating transplantable organs: From blastocyst complementation to interspecies chimeras. Development 2021, 148: dev195792.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tam PPL, Rossant J. Mouse embryonic chimeras: Tools for studying mammalian development. Development 2003, 130: 6155–6163.

Article  CAS  PubMed  Google Scholar 

Chen Y, Niu Y, Li Y, Ai Z, Kang Y, Shi H. Generation of Cynomolgus monkey chimeric fetuses using embryonic stem cells. Cell Stem Cell 2015, 17: 116–124.

Article  CAS  PubMed  Google Scholar 

Kang Y, Ai Z, Duan K, Si C, Wang Y, Zheng Y, et al. Improving cell survival in injected embryos allows primed pluripotent stem cells to generate chimeric Cynomolgus monkeys. Cell Rep 2018, 25: 2563-2576.e9.

Article  CAS  PubMed  Google Scholar 

Tachibana M, Sparman M, Ramsey C, Ma H, Lee HS, Penedo MCT, et al. Generation of chimeric Rhesus monkeys. Cell 2012, 148: 285–295.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cao J, Li W, Li J, Mazid MA, Li C, Jiang Y, et al. Live birth of chimeric monkey with high contribution from embryonic stem cells. Cell 2023, 186: 4996-5014.e24.

Article  CAS  PubMed  Google Scholar 

Wu J, Izpisua Belmonte JC. Dynamic pluripotent stem cell states and their applications. Cell Stem Cell 2015, 17: 509–525.

Article  CAS  PubMed  Google Scholar 

Gafni O, Weinberger L, Mansour AA, Manor YS, Chomsky E, Ben-Yosef D, et al. Derivation of novel human ground state naive pluripotent stem cells. Nature 2013, 504: 282–286.

Article  ADS  CAS  PubMed  Google Scholar 

Guo G, von Meyenn F, Rostovskaya M, Clarke J, Dietmann S, Baker D, et al. Epigenetic resetting of human pluripotency. Dev Camb Engl 2017, 144: 2748–2763.

CAS  Google Scholar 

Mazid MA, Ward C, Luo Z, Liu C, Li Y, Lai Y, et al. Rolling back human pluripotent stem cells to an eight-cell embryo-like stage. Nature 2022, 605: 315–324.

Article  ADS  CAS  PubMed  Google Scholar 

Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah DA, Reddy J, et al. Systematic identification of culture conditions for induction and maintenance of naive human pluripotency. Cell Stem Cell 2014, 15: 471–487.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, et al. Derivation of pluripotent stem cells with in vivo embryonic and extraembryonic potency. Cell 2017, 169: 243-257.e25.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ma H, Zhai J, Wan H, Jiang X, Wang X, Wang L, et al. In vitro culture of cynomolgus monkey embryos beyond early gastrulation. Science 2019, 366: eaax7890.

Article  CAS  PubMed  Google Scholar 

Niu Y, Sun N, Li C, Lei Y, Huang Z, Wu J, et al. Dissecting primate early post-implantation development using long-term in vitro embryo culture. Science 2019, 366: eaaw5754.

Article  CAS  PubMed  Google Scholar 

Zheng C, Hu Y, Sakurai M, Pinzon-Arteaga CA, Li J, Wei Y, et al. Cell competition constitutes a barrier for interspecies chimerism. Nature 2021, 592: 272–276.

Article  ADS  CAS  PubMed  Google Scholar 

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