Spinal nerve transection-induced upregulation of SAP97 via promoting membrane trafficking of GluA1-containing AMPA receptors in the dorsal horn contributes to the pathogenesis of neuropathic pain

Keywords

Synapse-associated protein-97

GluA1-containing AMPARs

Neuropathic pain

Spinal cord

Spinal nerve transection

AbbreviationSNT

spinal nerve transection

SAP97

synapse-associated protein-97

AMPARs

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors

MAGUKs

membrane-associated guanylate kinase homologs

NMDAR

N-methyl-d-aspartate receptor

PWT

paw withdrawal threshold

PWL

paw withdrawal latency

SPF

Specific Pathogen-Free.

Data availability

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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