Andersen B, Goldsmith GH, Spagnuolo PJ. Neutrophil adhesive dysfunction in diabetes mellitus; the role of cellular and plasma factors. J Lab Clin Med. 1988;111:275–85.

CAS  PubMed  Google Scholar 

Tater D, Tepaut B, Bercovici JP, Youinou P. Polymorphonuclear cell derangements in type I diabetes. Horm Metab Res. 1987;19:642–7.

Article  CAS  PubMed  Google Scholar 

Molenaar DM, Palumbo PJ, Wilson WR, Ritts RE Jr. Leukocyte chemotaxis in diabetic patients and their nondiabetic first-degree relatives. Diabetes. 1976;25:880–3.

CAS  PubMed  Google Scholar 

Mowat A, Baum J. Chemotaxis of polymorphonuclear leukocytes from patients with diabetes mellitus. N Engl J Med. 1971;284:621–7.

Article  CAS  PubMed  Google Scholar 

Delamaire M, Maugendre D, Moreno M, Le Goff MC, Allannic H, Genetet B. Impaired leucocyte functions in diabetic patients. Diabet Med. 1997;14:29–34.

Article  CAS  PubMed  Google Scholar 

Rayfield EJ, Ault MJ, Keusch GT, Brothers MJ, Nechemias C, Smith H. Infection and diabetes: the case for glucose control. Am J Med. 1982;72:439–50.

Article  CAS  PubMed  Google Scholar 

Bagdade JD, Root RK, Bulger RJ. Impaired leukocyte function in patients with poorly controlled diabetes. Diabetes. 1974;23:9–15.

Article  CAS  PubMed  Google Scholar 

Naghibi M, Smith RP, Baltch AL, Gates SA, Wu DH, Hammer MC, Michelsen PB. The effect of diabetes mellitus on chemotactic and bactericidal activity of human polymorphonuclear leukocytes. Diabetes Res Clin Pract. 1987;4:27–35.

Article  CAS  PubMed  Google Scholar 

Tan JS, Anderson JL, Watanakunakorn C, Phair JP. Neutrophil dysfunction in diabetes mellitus. J Lab Clin Med. 1975;85:26–33.

CAS  PubMed  Google Scholar 

Negishi K, Gupta S, Chandy KG, Waldeck N, Kershnar A, Buckingham B, Charles MA. Interferon responsiveness of natural killer cells in type I human diabetes. Diabetes Res. 1988;7:49–52.

CAS  PubMed  Google Scholar 

Black CT, Hennessey PJ, Andrassy RJ. Short-term hyperglycemia depresses immunity through nonenzymatic glycosylation of circulating immunoglobulin. J Trauma. 1990;30:830–3.

Article  CAS  PubMed  Google Scholar 

Saiepour D, Sehlin J, Oldenborg PA. Hyperglycemia-induced protein kinase C activation inhibits phagocytosis of C3b- and immunoglobulin g-opsonized yeast particles in normal human neutrophils. Exp Diabesity Res. 2003;4:125–32.

Article  PubMed  PubMed Central  Google Scholar 

Nojima I, Eikawa S, Tomonobu N, Hada Y, Kajitani N, Teshigawara S, Miyamoto S, Tone A, Uchida HA, Nakatsuka A, Eguchi J, Shikata K, Udono H, Wada J. Dysfunction of CD8 + PD-1 + T cells in type 2 diabetes caused by the impairment of metabolism-immune axis. Sci Rep. 2020;10:14928.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun P, Jin Q, Nie S, Jia S, Li Y, Li X, Guo F. Unlike PDL-1 PD-1 is Downregulated on partial immune cells in type diabetes. J Diabetes Res. 2019;2019:5035261.

Article  PubMed  PubMed Central  Google Scholar 

Duke-Cohan JS, Morimoto C, Rocker JA, Schlossman SF. A novel form of dipeptidylpeptidase IV found in human serum. Isolation, characterization, and comparison with T lymphocyte membrane dipeptidylpeptidase IV (CD26). J Biol Chem. 1995;270:14107–14.

Article  CAS  PubMed  Google Scholar 

Boonacker EP, Wierenga EA, Smits HH, Van Noorden CJ. CD26/DPPIV signal transduction function, but not proteolytic activity, is directly related to its expression level on human Th1 and Th2 cell lines as detected with living cell cytochemistry. J Histochem Cytochem. 2002;50:1169–77.

Article  CAS  PubMed  Google Scholar 

Lee SA, Kim YR, Yang EJ, Kwon E-J, Kim SH, Kang SH, Park DB, Oh B-C, Kim J, Heo ST, Koh G, Lee DH. CD26/DPP4 levels in peripheral blood and T cells in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab. 2013;98:2553–61.

Article  CAS  PubMed  Google Scholar 

Iijima T, Kato K, Jojima T, Tomotsune T, Fukushima M, Suzuki K, Aso Y. Circulating CD4+PD-1+ and CD8+PD-1+ T cells are profoundly decreased at the onset of fulminant type 1 diabetes and are restored by treatment, contrasting with CD4+CD25+FoxP3+ regulatory T cells. Diabetes Res Clin Pract. 2017;133:10–2.

Article  CAS  PubMed  Google Scholar 

Rothman KJ. No adjustments are needed for multiple comparisons. Epidemiology. 1990;1:43–6.

Article  CAS  PubMed  Google Scholar 

Fujisawa R, Haseda F, Tsutsumi C, Hiromine Y, Noso S, Kawabata Y, Mitsui S, Terasaki J, Ikegami H, Imagawa A, Hanafusa T. Low programmed cell death-1 (PD-1) expression in peripheral CD4(+) T cells in Japanese patients with autoimmune type 1 diabetes. Clin Exp Immunol. 2015;180:452–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shi B, Du X, Wang Q, Chen Y, Zhang X. Increased PD-1 on CD4(+)CD28(-) T cell and soluble PD-1 ligand-1 in patients with T2DM: association with atherosclerotic macrovascular diseases. Metabolism. 2013;62:778–85.

Article  CAS  PubMed  Google Scholar