Farjana HN, Chandrasekaran SC, Gita B (2014) Effect of oral curcuma gel in gingivitis management - a pilot study. J Clin Diagn Res 8:ZC08-10. https://doi.org/10.7860/JCDR/2014/8784.5235

Article  PubMed  PubMed Central  Google Scholar 

Najeeb S, Zafar MS, Khurshid Z et al (2016) The role of nutrition in periodontal health: an update. Nutrients 8:530. https://doi.org/10.3390/nu8090530

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kornman KS (2008) Mapping the pathogenesis of periodontitis: a new look. J Periodontol 79:1560–1568. https://doi.org/10.1902/jop.2008.080213

Article  CAS  PubMed  Google Scholar 

Anuradha BR, Bai YD, Sailaja S et al (2015) Evaluation of anti-inflammatory effects of curcumin gel as an adjunct to scaling and root planing: a clinical study. J Int Oral Health 7:90–93

CAS  PubMed  PubMed Central  Google Scholar 

Nagasri M, Madhulatha M, Musalaiah SV et al (2015) Efficacy of curcumin as an adjunct to scaling and root planning in chronic periodontitis patients: a clinical and microbiological study. J Pharm Bioallied Sci 7:S554–S558. https://doi.org/10.4103/0975-7406.163537

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hugar SS, Patil S, Metgud R et al (2016) Influence of application of chlorhexidine gel and curcumin gel as an adjunct to scaling and root planing: a interventional study. J Nat Sci Biol Med 7:149–154. https://doi.org/10.4103/0976-9668.184701

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ravishankar PL, Kumar YP, Anila EN et al (2017) Effect of local application of curcumin and ornidazole gel in chronic periodontitis patients. Int J Pharm Investig 7:188–192. https://doi.org/10.4103/jphi.JPHI_82_17

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kandwal A, Mamgain RK, Mamgain P (2015) Comparative evaluation of turmeric gel with 2% chlorhexidine gluconate gel for treatment of plaque induced gingivitis: a randomized controlled clinical trial. Ayu 36:145–150. https://doi.org/10.4103/0974-8520.175537

Article  PubMed  PubMed Central  Google Scholar 

Behal R, Mali AM, Gilda SS et al (2011) Evaluation of local drug-delivery system containing 2% whole turmeric gel used as an adjunct to scaling and root planing in chronic periodontitis: a clinical and microbiological study. J Indian Soc Periodontol 15:35–38

Article  PubMed  PubMed Central  Google Scholar 

Higgins JPT, Savović J, Page M et al (2019) Assessing risk of bias in a randomized trial. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (eds) Cochrane Handbook for Systematic Reviews of Interventions, 2nd edn. Wiley-Blackwell, Chichester, pp 205–228

Chapter  Google Scholar 

Pérez-Pacheco CG, Fernandes NAR, Primo FL et al (2021) Local application of curcumin-loaded nanoparticles as an adjunct to scaling and root planing in periodontitis: randomized, placebo-controlled, double-blind split-mouth clinical trial. Clin Oral Investig 25:3217–3227. https://doi.org/10.1007/s00784-020-03652-3

Article  PubMed  Google Scholar 

Saini K, Chopra P, Bhardwaj A et al (2021) Comparative clinical evaluation of two local drug delivery agents (neem chip and turmeric chip) in chronic periodontitis: an experimental study. World J Dent 12:138–143

Article  Google Scholar 

Siddharth M, Singh P, Gupta R et al (2020) A comparative evaluation of subgingivally delivered 2% curcumin and 0.2% chlorhexidine gel adjunctive to scaling and root planing in chronic periodontitis. J Contemp Dent Pract 21:494–499

Article  PubMed  Google Scholar 

Raghava KV, Sistla KP, Narayan SJ et al (2019) Efficacy of curcumin as an adjunct to scaling and root planing in chronic periodontitis patients: a randomized controlled clinical trial. J Contemp Dent Pract 20:842–846

Article  PubMed  Google Scholar 

Anitha V, Rajesh P, Shanmugam M et al (2015) Comparative evaluation of natural curcumin and synthetic chlorhexidine in the management of chronic periodontitis as a local drug delivery: a clinical and microbiological study. Indian J Dent Res 26:53–56. https://doi.org/10.4103/0970-9290.156806

Article  CAS  PubMed  Google Scholar 

Bhatia M, Urolagin SS, Pentyala KB et al (2014) Novel therapeutic approach for the treatment of periodontitis by curcumin. J Clin Diagn Res 8:ZC65–ZC69. https://doi.org/10.7860/JCDR/2014/8231.5343

Article  CAS  PubMed  PubMed Central  Google Scholar 

Amin I, Ahmed A, Amanat A et al (2020) Anti-inflammatory effect of local application of curcuma gel in patients of chronic periodontitis. Med Forum 31:95–98

Google Scholar 

Hewlings SJ, Kalman DS (2017) Curcumin: a review of its effects on human health. Foods 6:92. https://doi.org/10.3390/foods6100092

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sahebkar A, Serban M, Ursoniu S et al (2015) Effect of curcuminoids on oxidative stress: a systematic review and meta-analysis of randomized controlled trials. J Funct Foods 18:898–909. https://doi.org/10.1016/j.jff.2015.01.005

Article  CAS  Google Scholar 

Aggarwal BB, Surh YJ, Shishodia S (2007) The molecular targets and therapeutic uses of curcumin in health and disease. Springer, New York

Book  Google Scholar 

Habiboallah G, Nasroallah S, Mahdi Z et al (2008) Histological evaluation of Curcuma longa-ghee formulation and hyaluronic acid on gingival healing in dog. J Ethnopharmacol 120:335–341. https://doi.org/10.1016/j.jep.2008.09.011

Article  CAS  PubMed  Google Scholar 

Dai C, Wang Y, Sharma G et al (2020) Polymyxins-curcumin combination antimicrobial therapy: safety implications and efficacy for infection treatment. Antioxidants (Basel) 9:506. https://doi.org/10.3390/antiox9060506

Article  CAS  PubMed  Google Scholar 

Kumari A, Raina N, Wahi A et al (2022) Wound-healing effects of curcumin and its nanoformulations: a comprehensive review. Pharmaceutics 14:2288. https://doi.org/10.3390/pharmaceutics14112288

Article  CAS  PubMed  PubMed Central  Google Scholar