Uncovering the role of aquaporin and chromobox family members as potential biomarkers in head and neck squamous cell carcinoma via integrative multiomics and in silico approach

Baumann C, Zhang X, De La Fuente R (2020) Loss of CBX2 induces genome instability and senescence-associated chromosomal rearrangements. J Cell Biol 219:e201910149. https://doi.org/10.1083/jcb.201910149

Article  CAS  PubMed  PubMed Central  Google Scholar 

Berman HM, Westbrook J, Feng Z et al (2000) The protein data bank. Nucleic Acids Res 28:235–242. https://doi.org/10.1093/nar/28.1.235

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhat GR, Hyole RG, Li J (2021) Head and neck cancer: current challenges and future perspectives. Adv Cancer Res 152:67–102. https://doi.org/10.1016/bs.acr.2021.05.002

Article  CAS  PubMed  Google Scholar 

Bornstein S, White R, Malkoski S et al (2009) Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation. J Clin Invest JCI38854. https://doi.org/10.1172/JCI38854

Borsetto D, Tomasoni M, Payne K et al (2021) Prognostic significance of CD4+ and CD8+ tumor-infiltrating lymphocytes in head and neck squamous cell carcinoma: a meta-analysis. Cancers 13:781. https://doi.org/10.3390/cancers13040781

Article  CAS  PubMed  PubMed Central  Google Scholar 

Camahort R, Cowan CA (2012) Cbx proteins help ESCs walk the line between self-renewal and differentiation. Cell Stem Cell 10:4–6. https://doi.org/10.1016/j.stem.2011.12.011

Article  CAS  PubMed  Google Scholar 

Cerami E, Gao J, Dogrusoz U et al (2012) The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov 2:401–404. https://doi.org/10.1158/2159-8290.CD-12-0095

Article  PubMed  Google Scholar 

Chandrashekar DS, Bashel B, Balasubramanya SAH et al (2017) UALCAN: a portal for facilitating tumor subgroup gene expression and survival analyses. Neoplasia N Y N 19:649–658. https://doi.org/10.1016/j.neo.2017.05.002

Article  CAS  Google Scholar 

Chandrashekar DS, Karthikeyan SK, Korla PK et al (2022) UALCAN: an update to the integrated cancer data analysis platform. Neoplasia N Y N 25:18–27. https://doi.org/10.1016/j.neo.2022.01.001

Article  CAS  Google Scholar 

Chen Y, Tachibana O, Oda M et al (2006) Increased expression of aquaporin 1 in human hemangioblastomas and its correlation with cyst formation. J Neurooncol 80:219–225. https://doi.org/10.1007/s11060-005-9057-1

Article  CAS  PubMed  Google Scholar 

Chen EY, Tan CM, Kou Y et al (2013) Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool. BMC Bioinformatics 14:128. https://doi.org/10.1186/1471-2105-14-128

Article  PubMed  PubMed Central  Google Scholar 

Desai D, Pethe P (2020) Polycomb repressive complex 1: regulators of neurogenesis from embryonic to adult stage. J Cell Physiol 235:4031–4045. https://doi.org/10.1002/jcp.29299

Article  CAS  PubMed  Google Scholar 

Downs-Canner SM, Meier J, Vincent BG, Serody JS (2022) B Cell function in the tumor microenvironment. Annu Rev Immunol 40:169–193. https://doi.org/10.1146/annurev-immunol-101220-015603

Article  CAS  PubMed  Google Scholar 

Gcp van Z, Jpglm R, M T et al (2016) The HADDOCK2.2 web server: user-friendly integrative modeling of biomolecular complexes. J Mol Biol 428. https://doi.org/10.1016/j.jmb.2015.09.014

Guo X, Sun T, Yang M et al (2013) Prognostic value of combined aquaporin 3 and aquaporin 5 overexpression in hepatocellular carcinoma. BioMed Res Int 2013:1–7. https://doi.org/10.1155/2013/206525

Article  CAS  Google Scholar 

Györffy B, Lanczky A, Eklund AC et al (2010) An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients. Breast Cancer Res Treat 123:725–731. https://doi.org/10.1007/s10549-009-0674-9

Article  CAS  PubMed  Google Scholar 

Győrffy B (2023) Discovery and ranking of the most robust prognostic biomarkers in serous ovarian cancer. GeroScience. https://doi.org/10.1007/s11357-023-00742-4

Article  PubMed  PubMed Central  Google Scholar 

Hibuse T, Maeda N, Nagasawa A, Funahashi T (2006) Aquaporins and glycerol metabolism. Biochim Biophys Acta 1758:1004–1011. https://doi.org/10.1016/j.bbamem.2006.01.008

Article  CAS  PubMed  Google Scholar 

Hoque MO, Soria J-C, Woo J et al (2006) Aquaporin 1 is overexpressed in lung cancer and stimulates NIH-3T3 cell proliferation and anchorage-independent growth. Am J Pathol 168:1345–1353. https://doi.org/10.2353/ajpath.2006.050596

Article  CAS  PubMed  PubMed Central  Google Scholar 

Iqbal MA, Siddiqui S, Ur Rehman A et al (2021) Multiomics integrative analysis reveals antagonistic roles of CBX2 and CBX7 in metabolic reprogramming of breast cancer. Mol Oncol 15:1450–1465. https://doi.org/10.1002/1878-0261.12894

Article  CAS  PubMed  PubMed Central  Google Scholar 

Javed M, Bukhari RS, Rasool R et al (2023) Screening of four signature genes for clinical testing through bioinformatics and in vitro methods in head and neck squamous cell carcinoma. Am J Cancer Res 13:1826–1844

CAS  PubMed  PubMed Central  Google Scholar 

Johnson DE, Burtness B, Leemans CR et al (2020) Head and neck squamous cell carcinoma. Nat Rev Dis Primer 6:92. https://doi.org/10.1038/s41572-020-00224-3

Article  Google Scholar 

Jumper J, Evans R, Pritzel A et al (2021) Highly accurate protein structure prediction with AlphaFold. Nature 596:583–589. https://doi.org/10.1038/s41586-021-03819-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

Keenan AB, Torre D, Lachmann A et al (2019) ChEA3: transcription factor enrichment analysis by orthogonal omics integration. Nucleic Acids Res 47:W212–W224. https://doi.org/10.1093/nar/gkz446

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kuleshov MV, Jones MR, Rouillard AD et al (2016) Enrichr: a comprehensive gene set enrichment analysis web server 2016 update. Nucleic Acids Res 44:W90-97. https://doi.org/10.1093/nar/gkw377

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kundu SK, Nestor M (2012) Targeted therapy in head and neck cancer. Tumour Biol J Int Soc Oncodevelopmental Biol Med 33:707–721. https://doi.org/10.1007/s13277-012-0350-2

Article  CAS  Google Scholar 

Lánczky A, Győrffy B (2021) Web-based survival analysis tool tailored for medical research (KMplot): development and implementation. J Med Internet Res 23:e27633. https://doi.org/10.2196/27633

Article  PubMed  PubMed Central  Google Scholar 

Larsson J, Karlsson S (2005) The role of Smad signaling in hematopoiesis. Oncogene 24:5676–5692. https://doi.org/10.1038/sj.onc.1208920

Article  CAS  PubMed  Google Scholar 

Li T, Fu J, Zeng Z et al (2020) TIMER2.0 for analysis of tumor-infiltrating immune cells. Nucleic Acids Res 48:W509–W514. https://doi.org/10.1093/nar/gkaa407

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li W, Chen H, Wang Z et al (2022) Chromobox 4 (CBX4) promotes tumor progression and stemness via activating CDC20 in gastric cancer. J Gastrointest Oncol 13:1058–1072

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liberati NT, Datto MB, Frederick JP et al (1999) Smads bind directly to the Jun family of AP-1 transcription factors. Proc Natl Acad Sci 96:4844–4849. https://doi.org/10.1073/pnas.96.9.4844

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu S, Zhang S, Jiang H et al (2013) Co-expression of AQP3 and AQP5 in esophageal squamous cell carcinoma correlates with aggressive tumor progression and poor prognosis. Med Oncol 30:636. https://doi.org/10.1007/s12032-013-0636-2

Article  CAS  PubMed  Google Scholar 

Marlar S, Jensen HH, Login FH, Nejsum LN (2017) Aquaporin-3 in cancer. Int J Mol Sci 18:2106. https://doi.org/10.3390/ijms18102106

Article  CAS  PubMed  PubMed Central  Google Scholar 

Matsuo K, Kawano K (2014) Immunohistochemical distribution and morphometric analysis of aquaporin-3 in oral squamous cell carcinoma. Int J Oral Maxillofac Surg 43:13–21. https://doi.org/10.1016/j.ijom.2013.05.022

Article  CAS  PubMed  Google Scholar 

Millet C, Zhang YE (2007) Roles of Smad3 in TGF-β signaling during carcinogenesis. Crit Rev Eukaryot Gene Expr 17:281–293. https://doi.org/10.1615/CritRevEukarGeneExpr.v17.i4.30

Article  CAS  PubMed  PubMed Central  Google Scholar 

Moon C, Soria J-C, Jang SJ et al (2003) Involvement of aquaporins in colorectal carcinogenesis. Oncogene 22:6699–6703. https://doi.org/10.1038/sj.onc.1206762

留言 (0)

沒有登入
gif