Di Mauro G. Department of Human Pathology “G. Barresi”, University of Messina, Messina, Italy , Musarra M. Department of Human Pathology “G. Barresi”, University of Messina, Messina, Italy , Similia S. D. Department of Human Pathology “G. Barresi”, University of Messina, Messina, Italy , Puzzolo D. Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy , Minutoli L. Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy , Morace C. Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy , Di Giovanni N. Department of Human Pathology “G. Barresi”, University of Messina, Messina, Italy , Urzì Brancati V. Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy