Methylcobalamin prevents mutant superoxide dismutase-1-induc... : NeuroReport

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Erratum

NeuroReport | DOI: 10.1097/WNR.0000000000001967 Metrics

In Fig. 2 of the article [1] the unit of the Methylcobalamin concentration was incorrectly indicated in the graph. Correct unit is ‘nM’ as written in the corrected figure below. The authors apologies for this error.

Fig. 2:

Methylcobalamin and riluzole treatment rescues hSOD1 (G93A)-mediated motor neuron loss in vitro. (A) Mouse ESC-derived motor neurons were co-cultured with wildtype or hSOD1 (G93A)-expressing astrocytes with drugs (0.1 µM, 1 µM, and 10 µM of riluzole or 1 nM, 10 nM, and 100 nM of methylcobalamin) or vehicle (control) for 2 days and then fixed for immunocytochemical staining. (B, C) Quantification data for the number of surviving MNs treated with riluzole (B) or methylcobalamin (C) shown in (A). The number of ISL1+ cells is indicated as a percentage of the wildtype astrocyte control. Each experiment was performed in duplicate as three independent experiments (n = 3). Data are represented as mean ± standard error of the mean. Statistical significance (test sample vs. human SOD1 (G93A) control) was determined using one-way analysis of variance (*P < 0.05, **P < 0.01).

Reference 1. Ito S, Izumi Y, Niidome T, Ono Y. Methylcobalamin prevents mutant superoxide dismutase-1-induced motor neuron death in vitro. Neuroreport 2017; 28:101–107. Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved. Article Level Metrics