This protocol outlines a register-based cohort study utilizing Danish Hip Arthroplasty Register data from 1995 to 2022. Focusing on adult patients undergoing primary total hip arthroplasty (THA), the study categorizes revisions, particularly periprosthetic joint infections (PJI), into Debridement, antibiotics, and implant retention (DAIR), one-stage, and two-stage approaches. Annual revision numbers and the risk of a second revision after each primary type will be analyzed. The study’s strengths lie in its comprehensive examination of various PJI revision methods and an extended recording period, leveraging the DHR’s high completeness rates. While acknowledging potential uncertainties, the study offers valuable insights into THA revision trends, aiding in clinical practice optimization and improving patient outcomes.

Study registration Privacy identifier p-2023-14990

Protocol uploaded to OSF: Not yet uploaded

Budget The costs of the study are limited to the salary of the investigators, which is paid by the orthopedic department.

The authors have declared no competing interest.

This study did not receive any funding.

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Yes

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

The institutional review board of the Capitol of Denmark gave ethical approval for this work (reference p-2023-14990).

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

Yes

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

Yes

I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.

Yes

All data produced in the present study can be obtained from Danish Hip Register.