Ahn H, Moon B, Park M, Kim J (2020) KDM3A regulates slug expression to promote the invasion of MCF7 Breast cancer cells in hypoxia. Oncol Lett 20(6) Article 335. https://doi.org/10.3892/ol.2020.12199

Balazy KE, Benitez CM, Gutkin PM, Jacobson CE, von Eyben R, Horst KC (2019) Association between primary language, a lack of mammographic screening, and later stage Breast cancer presentation. Cancer 125(12):2057–2065. https://doi.org/10.1002/cncr.32027

Article  PubMed  Google Scholar 

Berke TP, Slight SH, Hyder SM (2022) Role of reactivating mutant p53 protein in suppressing growth and Metastasis of Triple-negative Breast Cancer. Oncotargets and Therapy 15:23–30. https://doi.org/10.2147/Ott.S342292

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bongiovanni A, Foca F, Fantini M, Forcignano MR, Artioli F, Berardi R, Campadelli E, Procopio G, Silvestris F, Riva N, Gurrieri L, Debonis SA, Di Menna G, Fausti V, Recine F, Vespignani R, Ibrahim T (2021) First prospective data on Breast cancer patients from the multicentre Italian bone Metastasis database. Sci Rep 11(1):4329. https://doi.org/10.1038/s41598-021-83749-1

Article  PubMed  PubMed Central  CAS  Google Scholar 

Cao W, Chen HD, Yu YW, Li N, Chen WQ (2021) Changing profiles of cancer burden worldwide and in China: a secondary analysis of the global cancer statistics 2020. Chin Med J 134(7):783–791. https://doi.org/10.1097/Cm9.0000000000001474

Article  PubMed  PubMed Central  Google Scholar 

Coleman R, Finkelstein DM, Barrios C, Martin M, Iwata H, Hegg R, Glaspy J, Perianez AM, Tonkin K, Deleu I, Sohn J, Crown J, Delaloge S, Dai T, Zhou Y, Jandial D, Chan A (2020a) Adjuvant denosumab in early Breast cancer (D-CARE): an international, multicentre, randomised, controlled, phase 3 trial. Lancet Oncol 21(1):60–72. https://doi.org/10.1016/S1470-2045(19)30687-4

Article  PubMed  CAS  Google Scholar 

Coleman RE, Croucher PI, Padhani AR, Clezardin P, Chow E, Fallon M, Guise T, Colangeli S, Capanna R, Costa L (2020b) Bone metastases. Nat Reviews Disease Primers 6(1). https://doi.org/10.1038/s41572-020-00216-3

Feng CL, Zhang HS, Chen JM, Wang SQ, Xin YR, Qu Y, Zhang Q, Ji W, Yamashita F, Rui MJ, Xu XM (2019) Ratiometric co-encapsulation and co-delivery of doxorubicin and paclitaxel by tumor-targeted lipodisks for combination therapy of Breast cancer. Int J Pharm 560:191–204. https://doi.org/10.1016/j.ijpharm.2019.02.009

Article  PubMed  CAS  Google Scholar 

Herzog M, Josseaux E, Dedeurwaerder S, Calonne E, Volkmar M, Fuks F (2012) The histone demethylase Kdm3a is essential to progression through differentiation. Nucleic Acids Res 40(15):7219–7232. https://doi.org/10.1093/nar/gks399

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ikeda S, Kitadate A, Abe F, Takahashi N, Tagawa H (2018) Hypoxia-inducible KDM3A addiction in Multiple Myeloma. Blood Adv 2(4):323–334. https://doi.org/10.1182/bloodadvances.2017008847

Article  PubMed  PubMed Central  CAS  Google Scholar 

Invernizzi M, Kim J, Fusco N (2020) Editorial: quality of life in Breast Cancer patients and survivors. Front Oncol 10:620574. https://doi.org/10.3389/fonc.2020.620574

Article  PubMed  PubMed Central  Google Scholar 

Jeon HY, Ryu H, Pornour M, Qi JF (2022) Histone demethylase JMJD1A in cancer progression and therapeutic resistance. Mol Carcinog. https://doi.org/10.1002/mc.23390

Article  PubMed  PubMed Central  Google Scholar 

Lee HK, Ismail T, Kim C, Kim Y, Park JW, Kwon OS, Kang BS, Lee DS, Kwon T, Park TJ, Lee HS (2019) Lysine demethylase 3a in craniofacial and neural development during Xenopus embryogenesis. Int J Mol Med 43(2):1105–1113. https://doi.org/10.3892/ijmm.2018.4024

Article  PubMed  CAS  Google Scholar 

Li YN, Yang W, Wu B, Liu YQ, Li DB, Guo YT, Fu HY, Li Y (2017) KDM3A promotes inhibitory cytokines secretion by participating in TLR4 regulation of Foxp3 transcription in lung adenocarcinoma cells. Oncol Lett 13(5):3529–3537. https://doi.org/10.3892/ol.2017.5949

Article  PubMed  PubMed Central  CAS  Google Scholar 

Li G, Wang D, Ma W, An K, Liu Z, Wang X, Yang C, Du F, Han X, Chang S, Yu H, Zhang Z, Zhao Z, Zhang Y, Wang J, Sun Y (2018) Transcriptomic and epigenetic analysis of Breast cancer stem cells. Epigenomics 10(6):765–783. https://doi.org/10.2217/epi-2018-0008

Article  PubMed  CAS  Google Scholar 

Li Z, Xia J, Fang M, Xu Y (2019) Epigenetic regulation of Lung cancer cell proliferation and migration by the chromatin remodeling protein BRG1. Oncogenesis 8(11):66. https://doi.org/10.1038/s41389-019-0174-7

Article  PubMed  PubMed Central  CAS  Google Scholar 

Liu J, Li D, Zhang X, Li Y, Ou J (2020) Histone demethylase KDM3A promotes Cervical Cancer Malignancy through the ETS1/KIF14/Hedgehog Axis. Onco Targets Ther 13:11957–11973. https://doi.org/10.2147/OTT.S276559

Article  PubMed  PubMed Central  CAS  Google Scholar 

Liu J, Feng Y, Zeng X, He M, Gong Y, Liu Y (2021) Extracellular vesicles-encapsulated let-7i shed from bone mesenchymal stem cells suppress Lung cancer via KDM3A/DCLK1/FXYD3 axis. J Cell Mol Med 25(4):1911–1926. https://doi.org/10.1111/jcmm.15866

Article  PubMed  CAS  Google Scholar 

Liu P, Wang Z, Ou X, Wu P, Zhang Y, Wu S, Xiao X, Li Y, Ye F, Tang H (2022) The FUS/circEZH2/KLF5/ feedback loop contributes to CXCR4-induced liver Metastasis of Breast cancer by enhancing epithelial-mesenchymal transition. Mol Cancer 21(1):198. https://doi.org/10.1186/s12943-022-01653-2

Article  PubMed  PubMed Central  CAS  Google Scholar 

Man YG, Mannion C, Stojadinovic A, Peoples GE, Cho WC, Fu SW, Tan X, Hsiao YH, Liu A, Semczuk A, Zarogoulidis P, Gapeev AB, Deng X, Peng X, Reva BA, Omelchenko T, Wang J, Song G, Chen T (2023) The most likely but largely ignored triggering factor for breast (or all) cancer invasion. J Cancer 14(4):573–590. https://doi.org/10.7150/jca.82291

Article  PubMed  PubMed Central  Google Scholar 

Mariotto AB, Etzioni R, Hurlbert M, Penberthy L, Mayer M (2017) Estimation of the number of women living with metastatic Breast Cancer in the United States. Cancer Epidemiol Biomarkers Prev 26(6):809–815. https://doi.org/10.1158/1055-9965.EPI-16-0889

Article  PubMed  PubMed Central  Google Scholar 

Ning K, Shao Y, He Y, Wang F, Cui X, Liu F, Li D, Li F (2020) Histone demethylase Jumonji domain-containing 1A inhibits proliferation and progression of gastric cancer by upregulating runt-related transcription factor 3. Cancer Sci 111(10):3679–3692. https://doi.org/10.1111/cas.14594

Article  PubMed  PubMed Central  CAS  Google Scholar 

Qin L, Xu YX, Yu XB, Toneff MJ, Li DB, Liao L, Martinez JD, Li Y, Xu JM (2017) The histone demethylase Kdm3a is required for normal epithelial proliferation, ductal elongation and Tumor growth in the mouse mammary gland. Oncotarget 8(49):84761–84775. https://doi.org/10.18632/oncotarget.21380

Article  PubMed  PubMed Central  Google Scholar 

Ramadoss S, Guo G, Wang CY (2017a) Lysine demethylase KDM3A regulates Breast cancer cell invasion and apoptosis by targeting histone and the non-histone protein p53. Oncogene 36(1):47–59. https://doi.org/10.1038/onc.2016.174

Article  PubMed  CAS  Google Scholar 

Ramadoss S, Sen S, Ramachandran I, Roy S, Chaudhuri G, Farias-Eisner R (2017b) Lysine-specific demethylase KDM3A regulates Ovarian cancer stemness and chemoresistance. Oncogene 36(11):1537–1545. https://doi.org/10.1038/onc.2016.320

Article  PubMed  CAS  Google Scholar 

Riggio AI, Varley KE, Welm AL (2021) The lingering mysteries of metastatic recurrence in Breast cancer. Br J Cancer 124(1):13–26. https://doi.org/10.1038/s41416-020-01161-4

Article  PubMed  Google Scholar 

Sechler M, Parrish JK, Birks DK, Jedlicka P (2017) The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and Metastasis. Oncogene 36(29):4150–4160. https://doi.org/10.1038/onc.2017.44

Article  PubMed  PubMed Central  CAS  Google Scholar 

Siegel RL, Miller KD, Jemal A (2020) Cancer statistics, 2020. CA Cancer J Clin 70(1):7–30. https://doi.org/10.3322/caac.21590

Article  PubMed  Google Scholar 

Sui Y, Li X, Oh S, Zhang B, Freeman WM, Shin S, Janknecht R (2020) Opposite roles of the JMJD1A Interaction Partners MDFI and MDFIC in Colorectal Cancer. Sci Rep 10(1):8710. https://doi.org/10.1038/s41598-020-65536-6

Article  PubMed  PubMed Central  CAS  Google Scholar 

Sui Y, Gu R, Janknecht R (2021) Crucial functions of the JMJD1/KDM3 epigenetic regulators in Cancer. Mol Cancer Res 19(1):3–13. https://doi.org/10.1158/1541-7786.MCR-20-0404

Article  PubMed  CAS  Google Scholar 

Sun LN, Yuan YB, Chen JL, Ma CL, Xu Y (2019) Brahma related gene 1 (BRG1) regulates Breast cancer cell migration and invasion by activating MUC1 transcription. Biochem Biophys Res Commun 511(3):536–543. https://doi.org/10.1016/j.bbrc.2019.02.088

Article  PubMed  CAS  Google Scholar 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F (2021) Global Cancer statistics 2020: GLOBOCAN estimates of incidence and Mortality Worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71(3):209–249. https://doi.org/10.3322/caac.21660

Article  PubMed  Google Scholar 

Wade MA, Jones D, Wilson L, Stockley J, Coffey K, Robson CN, Gaughan L (2015) The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in Breast cancer. Nucleic Acids Res 43(1):196–207.