Treatment Landscape of Renal Cell Carcinoma

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Choueiri TK, Powles T, Albiges L, et al. Cabozantinib plus nivolumab and ipilimumab in renal-cell carcinoma. N Engl J Med. 2023;388:1767–78. Triplet study which investigated ipilimumab/nivolumab/cabozantinib in first-line RCC.

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Choueiri T, Plimack ER, Powles T, et al. Phase 3 study of first-line treatment with pembrolizumab + belzutifan + lenvatinib or pembrolizumab/quavonlimab + lenvatinib versus pembrolizumab + lenvatinib for advanced renal cell carcinoma (RCC). J Clin Oncol. 2022;40:abstr TPS99. Ongoing trial of the triplet regimens in first-line RCC.

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