Centro Nacional de Investigaciones Cardiovasculares (CNIC), Calle Melchor Fernández Almagro, 3, 28029, Madrid, Spain

Rocío Párraga, Carlos Real, Inés García-Lunar, Gonzalo Pizarro, Ernesto González-Calvo, Juan Miguel Fernandez-Alvira, Jesús Martínez-Gómez & Rodrigo Fernández-Jiménez

Department of Cardiology, Hospital Universitario Clínico San Carlos, Madrid, Spain

Rocío Párraga, Carlos Real, Ernesto González-Calvo & Rodrigo Fernández-Jiménez

Cardiology Department, University Hospital La Moraleja, Madrid, Spain

Inés García-Lunar

CIBER de enfermedades cardiovasculares (CIBER-CV), Madrid, Spain

Inés García-Lunar, Gonzalo Pizarro & Rodrigo Fernández-Jiménez

Department of Cardiology, Hospital Ruber Juan Bravo Quironsalud UEM, Madrid, Spain

Gonzalo Pizarro

Philips Healthcare Spain, Madrid, Spain

Javier Sánchez-González

Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, Spain

Raquel Diaz-Munoz

RP performed recruitment of participants and consent process, made substantial contributions to the interpretation of data, and drafted the initial manuscript.

CR made substantial contribution to the design of the data collection tools, coordinated recruitment of participants and consent process, and made substantial contributions to the interpretation of data.

IG-L and GP performed imaging analyses and made substantial contributions to the interpretation of data.

JS-G designed the imaging protocol and made substantial contributions to the interpretation of data.

RD-M assisted with recruitment of participants and consent process, made substantial contributions to the acquisition of imaging and anthropometric data, and performed capillary blood tests.

EG-C assisted with recruitment of participants and consent process, made substantial contributions to the acquisition of imaging data, and performed analyses of quality assessment for acquired images.

JMF-A and JM-G conducted statistical analyses.

RF-J conceptualized, designed, and coordinated the overall study.

All authors revised the manuscript critically for relevant intellectual content, gave final approval of the version to be published, and agree to be accountable for all aspects of the work.

Correspondence to Rodrigo Fernández-Jiménez.