Abd-Elhakim YM, El Sharkawy NI, Gharib HSA, Hassan MA, Metwally MMM, Elbohi KM et al (2023) Neurobehavioral responses and toxic brain reactions of juvenile rats exposed to iprodione and chlorpyrifos, alone and in a mixture. Toxics 11,
Aboubakr M, Elshafae SM, Abdelhiee EY, Fadl SE, Soliman A, Abdelkader A et al (2021) Antioxidant and anti-inflammatory potential of thymoquinone and lycopene mitigate the chlorpyrifos-induced toxic neuropathy. Pharmaceuticals 14,
Abuelsaad ASA, Mohamed I, Allam G, Al-Solumani AA (2013) Antimicrobial and immunomodulating activities of hesperidin and ellagic acid against diarrheic aeromonas hydrophila in a murine model. Life Sci 93:714–722
Article CAS PubMed Google Scholar
Aebi H (1984) [13] catalase in vitro. Methods Enzymol 105:121–126
Article CAS PubMed Google Scholar
Albasher G, Almeer R, Alarifi S, Alkhtani S, Farhood M, Al-Otibi FO et al (2019) Nephroprotective role of beta vulgaris L. root extract against chlorpyrifos-induced renal injury in rats. Evidence-Based Complement Altern Med 2019:359561
Albasher G, Alsaleh AS, Alkubaisi N, Alfarraj S, Alkahtani S, Farhood M et al (2020) Red beetroot extract abrogates chlorpyrifos-induced cortical damage in rats. Oxid Med Cell Longev. 2963020
AlKahtane AA, Ghanem E, Bungau SG, Alarifi S, Ali D, AlBasher G et al (2020) Carnosic acid alleviates chlorpyrifos-induced oxidative stress and inflammation in mice cerebral and ocular tissues. Environ Sci Pollut Res 27:11663–11670
Benzer F, Kandemir FM, Kucukler S, Comaklı S, Caglayan C (2018) Chemoprotective effects of curcumin on doxorubicin-induced nephrotoxicity in wistar rats: by modulating inflammatory cytokines, apoptosis, oxidative stress and oxidative DNA damage. Arch Physiol Biochem 124:448–457
Article CAS PubMed Google Scholar
Botté ES, Jerry DR, Codi King S, Smith-Keune C, Negri AP (2012) Effects of chlorpyrifos on cholinesterase activity and stress markers in the tropical reef fish Acanthochromis polyacanthus. Mar Pollut Bull 65:384–393
Brasil FB, de Almeida FJS, Luckachaki MD, Dall’Oglio EL, de Oliveira MR (2021) Pinocembrin pretreatment counteracts the chlorpyrifos-induced HO-1 downregulation, mitochondrial dysfunction, and inflammation in the SH-SY5Y cells. Metab Brain Dis 36:2377–2391
Article CAS PubMed Google Scholar
Caglayan C, Demir Y, Kucukler S, Taslimi P, Kandemir FM, Gulçin İ (2019a) The effects of hesperidin on sodium arsenite-induced different organ toxicity in rats on metabolic enzymes as antidiabetic and anticholinergics potentials: a biochemical approach. J Food Biochem 43:e12720
Caglayan C, Kandemir FM, Yildirim S, Kucukler S, Eser G (2019b) Rutin protects mercuric chloride-induced nephrotoxicity via targeting of aquaporin 1 level, oxidative stress, apoptosis and inflammation in rats. J Trace Elem Med Biol 54:69–78
Article CAS PubMed Google Scholar
Caglayan C, Taslimi P, Türk C, Kandemir FM, Demir Y, Gulcin İ (2019c) Purification and characterization of the carbonic anhydrase enzyme from horse mackerel (Trachurus trachurus) muscle and the impact of some metal ions and pesticides on enzyme activity. Comp Biochem Physiol C: Toxicol Pharmacol 226:108605
Caglayan C, Taslimi P, Türk C, Gulcin İ, Kandemir FM, Demir Y et al (2020) Inhibition effects of some pesticides and heavy metals on carbonic anhydrase enzyme activity purified from horse mackerel (Trachurus trachurus) gill tissues. Environ Sci Pollut Res 27:10607–10616
Caglayan C, Kandemir FM, Darendelioğlu E, Küçükler S, Ayna A (2021) Hesperidin protects liver and kidney against sodium fluoride-induced toxicity through anti-apoptotic and anti-autophagic mechanisms. Life Sci 281:119730
Article CAS PubMed Google Scholar
Çelik H, Kandemir FM, Caglayan C, Özdemir S, Çomaklı S, Kucukler S et al (2020a) Neuroprotective effect of rutin against colistin-induced oxidative stress, inflammation and apoptosis in rat brain associated with the CREB/BDNF expressions. Mol Biol Rep 47:2023–2034
Çelik H, Kucukler S, Çomaklı S, Özdemir S, Caglayan C, Yardım A et al (2020b) Morin attenuates ifosfamide-induced neurotoxicity in rats via suppression of oxidative stress, neuroinflammation and neuronal apoptosis. Neurotoxicology 76:126–137
Ćupić Miladinović D, Prevendar Crnić A, Peković S, Dacić S, Ivanović S, Santibanez JF et al (2021) Recovery of brain cholinesterases and effect on parameters of oxidative stres and apoptosis in quails (Coturnix japonica) after chlorpyrifos and vitamin B1 administration. Chemico-Biol Interact 333:109312
Demirdağ R, Yerlikaya E, Aksakal E, Küfrevioğlu ÖI, Ekinci D (2012) Influence of pesticides on the pH regulatory enzyme, carbonic anhydrase, from European Seabass liver and bovine erythrocytes. Environ Toxicol Pharmacol 34:218–222
Ekinci Akdemir FN, Gülçin İ, Karagöz B, Soslu R, Alwasel SH (2016) A comparative study on the antioxidant effects of hesperidin and ellagic acid against skeletal muscle ischemia/reperfusion injury. J Enzyme Inhib Med Chem 31:114–118
Article CAS PubMed Google Scholar
El-Sayed NM, Ahmed AAM, Selim MAA (2018) Cytotoxic effect of chlorpyrifos is associated with activation of Nrf-2/HO-1 system and inflammatory response in tongue of male Wistar rats. Environ Sci Pollut Res 25:12072–12082
Ellman GL, Courtney KD, Andres V, Featherstone RM (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7:88–95
Article CAS PubMed Google Scholar
Emre Kızıl H, Gür C, Ayna A, Darendelioğlu E, Küçükler S, Sağ S (2023) Contribution of oxidative stress, apoptosis, endoplasmic reticulum stress and autophagy pathways to the ameliorative effects of hesperidin in NaF-induced testicular toxicity. Chem Biodivers 20:e202200982
Fereidouni S, Kumar RR, Chadha VD, Dhawan DK (2019) Quercetin plays protective role in oxidative induced apoptotic events during chronic chlorpyrifos exposure to rats. J Biochem Mol Toxicol 33:e22341
Ghahremani S, Soodi M, Atashi A (2018) Quercetin ameliorates chlorpyrifos-induced oxidative stress in the rat brain: possible involvment of PON2 pathway. J Food Biochem 42:e12530
Hassan AA, Bel Hadj Salah K, Fahmy EM, Mansour DA, Mohamed SAM, Abdallah AA et al (2022) Olive leaf extract attenuates chlorpyrifos-induced neuro- and reproductive toxicity in male albino rats. Life 12,
Hsu S-S, Lin Y-S, Chen H-C, Liang W-Z (2023) Involvement of oxidative stress-related apoptosis in chlorpyrifos-induced cytotoxicity and the ameliorating potential of the antioxidant vitamin E in human glioblastoma cells. Environ Toxicol 38:2143–2154
Article CAS PubMed Google Scholar
Kandemir FM, Ozkaraca M, Küçükler S, Caglayan C, Hanedan B (2018) Preventive effects of hesperidin on diabetic nephropathy induced by streptozotocin via modulating TGF-β1 and oxidative DNA damage. Toxin Reviews 37:287–293
Kaur S, Singla N, Dhawan DK (2019) Neuro-protective potential of quercetin during chlorpyrifos induced neurotoxicity in rats. Drug Chem Toxicol 42:220–230
Article CAS PubMed Google Scholar
Khalaf AA, Ogaly HA, Ibrahim MA, Abdallah AA, Zaki AR, Tohamy AF (2022) The reproductive injury and oxidative testicular toxicity induced by chlorpyrifos can be restored by zinc in male rats. Biol Trace Elem Res 200:551–559
Article CAS PubMed Google Scholar
Kızıl HE, Caglayan C, Darendelioğlu E, Ayna A, Gür C, Kandemir FM et al (2023) Morin ameliorates methotrexate-induced hepatotoxicity via targeting Nrf2/HO-1 and Bax/Bcl2/Caspase-3 signaling pathways. Mol Biol Rep 50:3479–3488
Koksal Z, Kalin R, Gulcin I, Ozdemir H (2018) Inhibitory effects of selected pesticides on peroxidases purified by affinity chromatography. Int J Food Prop 21:385–394
Küçükler S, Çomaklı S, Özdemir S, Çağlayan C, Kandemir FM (2021) Hesperidin protects against the chlorpyrifos-induced chronic hepato-renal toxicity in rats associated with oxidative stress, inflammation, apoptosis, autophagy, and up-regulation of PARP-1/VEGF. Environ Toxicol 36:1600–1617
Landis WG, Chu VR, Graham SE, Harris MJ, Markiewicz AJ, Mitchell CJ et al (2020) Integration of chlorpyrifos acetylcholinesterase inhibition, water temperature, and dissolved oxygen concentration into a regional scale multiple stressor risk assessment estimating risk to Chinook salmon. Integr Environ Assess Manag 16:28–42
Article CAS PubMed Google Scholar
Lawrence RA, Burk RF (1976) Glutathione peroxidase activity in selenium-deficient rat liver. Biochem Biophys Res Commun 71:952–958
Article CAS PubMed Google Scholar
Lionetto MG, Caricato R, Giordano ME (2020) Carbonic anhydrase sensitivity to pesticides: perspectives for biomarker development. Int J Mol Sci 21,
Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2 – ∆∆CT method. Methods 25:402–408
Article CAS PubMed Google Scholar
Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265–275
Article CAS PubMed Google Scholar
Mahmoud SM, Abdel Moneim AE, Qayed MM, El-Yamany NA (2019) Potential role of N-acetylcysteine on chlorpyrifos-induced neurotoxicity in rats. Environ Sci Pollut Res 26:20731–20741
Nandhini AR, Harshiny M, Gummadi SN (2021) Chlorpyrifos in environment and food: a critical review of detection methods and degradation pathways. Environ Science: Processes Impacts 23:1255–1277
Obeng E (2020) Apoptosis (programmed cell death) and its signals-A review. Brazilian J Biology 81:1133–1143
Owumi SE, Najophe ES, Otunla MT (2022) 3-Indolepropionic acid prevented chlorpyrifos-induced hepatorenal toxicities in rats by improving anti-inflammatory, antioxidant, and pro-apoptotic responses and abating DNA damage. Environ Sci Pollut Res 29:74377–74393
Ozturk Kurt B, Ozdemir S (2023) Selenium heals the chlorpyrifos-induced oxidative damage and antioxidant enzyme levels in the rat tissues. Biol Trace Elem Res 201:1772–1780
留言 (0)