Daniel Chung1, Colas Authié2 and Laure Blouin3 1SparingVision, Philadelphia, Pennsylvania 19103, USA 2StreetLab, Institut de la Vision, UMR 7210 CNRS - UPMC - INSERM - CHNO, 75012 Paris, France 3SparingVision, 75008 Paris, France Correspondence: daniel.chungsparingvision.com

In the field of clinical ophthalmology, many of the common visual function study end points do not effectively reflect the significant morbidity of inherited retinal diseases (IRDs) and its effect on the patient's quality of life. In the last decade, emphasis has been placed on the development and implementation of patient-performance or task-focused end points, that may have greater ability to demonstrate the improvement or preservation of the patient's quality of life provided by therapeutic interventions. This article reviews performance-based tools developed to assess functional vision, such as the multi-luminance mobility test (MLMT) or the functional low-vision observer-rated assessment (FLORA), and highlights some of the recent advancements used in clinical development for IRD or ocular interventional therapies.