Available online 1 June 2023, 105500

Infection with XBB.1.5 is not associated with higher risk of admission or need for supplemental oxygen compared to other Omicron subvariants

Lack of vaccination and older age are associated with higher risk of admission

The rapidity with which SARS-CoV-2 XBB variants rose to predominance has been alarming. We used a large cohort of patients diagnosed with Omicron infections between September 2022 and mid-February 2023 to evaluate the likelihood of admission or need for supplemental oxygen in patients infected with XBB variants. Our data showed no significant association between XBB or XBB.1.5 infections and admissions. Older age groups, lack of vaccination, immunosuppression and underlying heart, kidney, and lung disease showed significant associations with hospitalization.

Omicron

XBB

XBB.1.5

COVID-19

admission

© 2023 The Author(s). Published by Elsevier B.V.