Radical cystectomy (RC) remains the mainstay of treatment for muscle-invasive bladder cancer and is also gaining ground as a therapeutic option for high-risk non–muscle-invasive bladder cancer. Through the development of surgical technology and improvement in surgeons’ technique, this considerably morbid operation can be carried out completely robot assisted, in a safe and standardized manner. However, postoperative complications are inevitable [1]. The assessment of these complications is essential in order to minimize them, ensure patient safety, and improve care. The Clavien-Dindo classification (CDC) first described in 2004 was evaluated by the European Association of Urology (EAU) in 2018, and is now the main classification system for assessing perioperative morbidity and mortality [2], [3]. Although, the use of CDC helped a lot in minimizing systematic errors related to RC, the new techniques that surgeons try to implement in everyday practice (totally intracorporeal robotic-assisted urinary diversion), and the disparities of surgical competence and institutional quality of care may lead to under-reporting of complications. This study aims to systematically appraise the literature for RC complications and examine the factors that affect the occurrence of these incidents.