Initiative USBaJ. The Burden of Musculoskeletal Diseases in the United States (BMUS). Rosemont, IL; 2020.

Guglielmo D, Hootman JM, Boring MA, Murphy LB, Theis KA, Croft JB, et al. Symptoms of anxiety and depression among adults with arthritis - United States, 2015–2017. MMWR Morb Mortal Wkly Rep. 2018;67(39):1081–7.

Article  PubMed  PubMed Central  Google Scholar 

Murphy LB, Sacks JJ, Brady TJ, Hootman JM, Chapman DP. Anxiety and depression among US adults with arthritis: prevalence and correlates. Arthritis Care Res (Hoboken). 2012;64(7):968–76.

PubMed  Google Scholar 

Tunks ER, Crook J, Weir R. Epidemiology of chronic pain with psychological comorbidity: prevalence, risk, course, and prognosis. Can J Psychiatry. 2008;53(4):224–34.

Article  PubMed  Google Scholar 

Cheng AL, Schwabe M, Doering MM, Colditz GA, Prather H. The effect of psychological impairment on outcomes in patients with Prearthritic Hip Disorders: a systematic review and Meta-analysis. Am J Sports Med. 2019:363546519883246-.

Edwards RR, Klick B, Buenaver L, Max MB, Haythornthwaite JA, Keller RB, et al. Symptoms of distress as prospective predictors of pain-related sciatica treatment outcomes. Pain. 2007;130(1–2):47–55.

Article  PubMed  Google Scholar 

Lee H, Hübscher M, Moseley GL, Kamper SJ, Traeger AC, Mansell G, et al. How does pain lead to disability? A systematic review and meta-analysis of mediation studies in people with back and neck pain. Pain. 2015;156(6):988–97.

Article  PubMed  Google Scholar 

Alattas SA, Smith T, Bhatti M, Wilson-Nunn D, Donell S. Greater pre-operative anxiety, pain and poorer function predict a worse outcome of a total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. 2017;25(11):3403–10.

Article  PubMed  Google Scholar 

Zalikha AK, Karabon P, Hajj Hussein I, El-Othmani MM. Anxiety and Depression Impact on Inhospital Complications and Outcomes after total knee and hip arthroplasty: a propensity score-weighted retrospective analysis. J Am Acad Orthop Surg. 2021;29(20):873–84.

Article  PubMed  Google Scholar 

Henry JK, Barth K, Cororaton A, Hummel A, Cody EA, Mancuso CA, et al. Association of depression and anxiety with expectations and satisfaction in foot and ankle surgery. J Am Acad Orthop Surg. 2021;29(16):714–22.

Article  PubMed  Google Scholar 

Cronin KJ, Mair SD, Hawk GS, Thompson KL, Hettrich CM, Jacobs CA. Increased Health Care costs and opioid use in patients with anxiety and Depression Undergoing Rotator Cuff Repair. Arthroscopy. 2020;36(10):2655–60.

Article  PubMed  PubMed Central  Google Scholar 

Celestin J, Edwards RR, Jamison RN. Pretreatment psychosocial variables as predictors of outcomes following lumbar surgery and spinal cord stimulation: a systematic review and literature synthesis. Pain Med. 2009;10(4):639–53.

Article  PubMed  Google Scholar 

Knapp P, Layson JT, Mohammad W, Pizzimenti N, Markel DC. The Effects of Depression and anxiety on 90-day Readmission Rates after total hip and knee arthroplasty. Arthroplast Today. 2021;10:175–9.

Article  PubMed  PubMed Central  Google Scholar 

Miner H, Rijk L, Thomas J, Ring D, Reichel LM, Fatehi A. Mental-Health phenotypes and patient-reported outcomes in Upper-Extremity illness. J Bone Joint Surg Am. 2021;103(15):1411–6.

Article  PubMed  Google Scholar 

Centers for Medicare & Medicaid Services. Public Comment Summary Report: Clinician-Level and Clinician Group-Level Total Hip Arthroplasty (THA) and/or Total Knee Arthroplasty (TKA) Patient-Reporuted Outcome-Based Performance Measure (PRO-PM) 2022 [Available from: https://mmshub.cms.gov/sites/default/files/PC-Summary-THATKA-PROPM.pdf.

Siddiqi A, White PB, Mistry JB, Gwam CU, Nace J, Mont MA et al. Effect of Bundled payments and Health Care Reform as Alternative Payment Models in total joint arthroplasty: a clinical review. J Arthroplasty. 2017.

Ring D, Vranceanu AM. Editorial comment: Papers from the International Consortium for Mental and Social Health in Musculoskeletal Care. Clin Orthop Relat Res. 2022;480(2):246–7.

Article  PubMed  Google Scholar 

Vranceanu AM, Bakhshaie J, Reichman M, Ring D. A call for interdisciplinary collaboration to promote Musculoskeletal Health: the creation of the International Musculoskeletal Mental and Social Health Consortium (I-MESH). J Clin Psychol Med Settings. 2021.

Leo AJ, Schuelke MJ, Hunt DM, Metzler JP, Miller JP, Areán PA, et al. A Digital Mental Health intervention in an Orthopedic setting for patients with symptoms of Depression and/or anxiety: feasibility prospective cohort study. JMIR formative research. 2022;6(2):e34889.

Article  PubMed  PubMed Central  Google Scholar 

Leo AJ, Schuelke MJ, Hunt DM, Miller JP, Areán PA, Cheng AL. Digital Mental Health intervention plus Usual Care compared with Usual Care only and Usual Care Plus In-Person psychological counseling for orthopedic patients with symptoms of depression or anxiety: Cohort Study. JMIR formative research. 2022;6(5):e36203.

Article  PubMed  PubMed Central  Google Scholar 

Jacobs CA, Mace RA, Greenberg J, Popok PJ, Reichman M, Lattermann C, et al. Development of a mind body program for obese knee osteoarthritis patients with comorbid depression. Contemp Clin Trials Commun. 2021;21:100720.

Article  PubMed  PubMed Central  Google Scholar 

Bakhshaie J, Doorley J, Reichman M, Mace R, Laverty D, Matuszewski PE, et al. Optimizing the implementation of a multisite feasibility trial of a mind-body program in acute orthopedic trauma. Transl Behav Med. 2022;12(5):642–53.

Article  PubMed  PubMed Central  Google Scholar 

Vranceanu AM, Jacobs C, Lin A, Greenberg J, Funes CJ, Harris MB, et al. Results of a feasibility randomized controlled trial (RCT) of the Toolkit for Optimal Recovery (TOR): a live video program to prevent chronic pain in at-risk adults with orthopedic injuries. Pilot Feasibility Stud. 2019;5:30.

Article  PubMed  PubMed Central  Google Scholar 

Ring D. Mental and Social Health are Inseparable from Physical Health. J Bone Joint Surg Am. 2021;103(11):951–2.

Article  PubMed  Google Scholar 

Ring D. Priorities for advancing Mental and Social Health among People presenting for Care of Musculoskeletal symptoms: International Consortium for Mental and Social Health in Musculoskeletal Care. J Clin Psychol Med Settings. 2022.

Vranceanu AM, Beks RB, Guitton TG, Janssen SJ, Ring D. How do orthopaedic surgeons address psychological aspects of illness? The archives of bone and joint surgery. 2017;5(1):2–9.

Vranceanu AM, Bakhshaie J, Reichman M, Doorley J, Mace RA, Jacobs C, et al. Understanding barriers and facilitators to implementation of psychosocial care within orthopedic trauma centers: a qualitative study with multidisciplinary stakeholders from geographically diverse settings. Implement Sci Commun. 2021;2(1):102.

Article  PubMed  PubMed Central  Google Scholar 

Reichman M, Bakhshaie J, Grunberg VA, Doorley JD, Vranceanu AM. What are Orthopaedic Healthcare Professionals’ Attitudes toward addressing patient psychosocial factors? A mixed-methods investigation. Clin Orthop Relat Res. 2022;480(2):248–62.

Article  PubMed  Google Scholar 

Sagar I, Popok PJ, Reichman M, Lester EG, Doorley J, Bakhshaie J, et al. Orthopedic Providers’ Preferences for Education and Training on Psychosocial Clinical Research Initiatives: a qualitative investigation. J Patient Exp. 2022;9:23743735221092570.

PubMed  PubMed Central  Google Scholar 

Cheng AL, Leo AJ, Calfee RP, Dy CJ, Armbrecht MA, Abraham J. What are orthopaedic patients’ and clinical team members’ perspectives regarding whether and how to address Mental Health in the Orthopaedic Care setting? A qualitative investigation of patients with Neck or Back Pain. Clin Orthop Relat Res. 2022.

Global Burden of Disease Study 2013 Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the global burden of Disease Study 2013. Lancet. 2015;386(9995):743–800.

Article  PubMed Central  Google Scholar 

Centers for Disease Control and Prevention. National Ambulatory Medical Care Survey: 2010 Summary Table 2010. Accessed May 16., 2022. [Available from: https://www.cdc.gov/nchs/data/ahcd/namcs_summary/2010_namcs_web_tables.pdf].

Demyttenaere K, Bruffaerts R, Lee S, Posada-Villa J, Kovess V, Angermeyer MC, et al. Mental disorders among persons with chronic back or neck pain: results from the World Mental Health surveys. Pain. 2007;129(3):332–42.

Article  PubMed  Google Scholar 

Beleckas CM, Prather H, Guattery J, Wright M, Kelly M, Calfee RP. Anxiety in the orthopedic patient: using PROMIS to assess mental health. Qual Life Res. 2018.

Cella D, Yount S, Rothrock N, Gershon R, Cook K, Reeve B, et al. The patient-reported outcomes Measurement Information System (PROMIS): progress of an NIH Roadmap cooperative group during its first two years. Med Care. 2007;45(5 Suppl 1):3–S11.

Article  Google Scholar 

PROMIS, Depression. A brief guide to the PROMIS Depression instruments 2019 [updated February 28, 2019. Available from: http://www.healthmeasures.net/images/PROMIS/manuals/PROMIS_Depression_Scoring_Manual.pdf.

PROMIS, Anxiety. A brief guide to the PROMIS Anxiety instruments 2019 [updated March 1, 2019. Available from: http://www.healthmeasures.net/images/PROMIS/manuals/PROMIS_Anxiety_Scoring_Manual.pdf.

Harris PA, Taylor R, Minor BL, Elliott V, Fernandez M, O’Neal L, et al. The REDCap consortium: building an international community of software platform partners. J Biomed Inform. 2019;95:103208.

Article  PubMed  PubMed Central  Google Scholar 

Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377–81.

Article  PubMed  Google Scholar 

Baldry S, Wysa Receives FDA. Breakthrough Device Designation for AI-led Mental Health Conversational Agent: Business Wire; 2022 [Available from: https://www.businesswire.com/news/home/20220512005084/en/Wysa-Receives-FDA-Breakthrough-Device-Designation-for-AI-led-Mental-Health-Conversational-Agent.

Brooke J. SUS - a quick and dirty usability scale. Usability Eval Ind. 1996;189(194):4–7.

Google Scholar 

Usability.gov. System Usability Scale (SUS): U.S. General Services Administration. ; 2022 [Available from: https://www.usability.gov/how-to-and-tools/methods/system-usability-scale.html.

Firth J, Torous J, Nicholas J, Carney R, Rosenbaum S, Sarris J. Can smartphone mental health interventions reduce symptoms of anxiety? A meta-analysis of randomized controlled trials. J Affect Disord. 2017;218:15–22.

Article  PubMed  Google Scholar 

Karyotaki E, Efthimiou O, Miguel C, Bermpohl FMG, Furukawa TA, Cuijpers P, et al. Internet-based cognitive behavioral therapy for Depression: a systematic review and individual Patient Data Network Meta-analysis. JAMA psychiatry. 2021;78(4):361–71.

Article  PubMed  Google Scholar 

Cuijpers P, Donker T, Johansson R, Mohr DC, van Straten A, Andersson G. Self-guided psychological treatment for depressive symptoms: a meta-analysis. PLoS ONE. 2011;6(6):e21274.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Linardon J, Cuijpers P, Carlbring P, Messer M, Fuller-Tyszkiewicz M. The efficacy of app-supported smartphone interventions for mental health problems: a meta-analysis of randomized controlled trials. World psychiatry: official journal of the World Psychiatric Association (WPA). 2019;18(3):325–36.

Article  PubMed  Google Scholar 

Carlbring P, Andersson G, Cuijpers P, Riper H, Hedman-Lagerlöf E. Internet-based vs. face-to-face cognitive behavior therapy for psychiatric and somatic disorders: an updated systematic review and meta-analysis. Cogn Behav Ther. 2018;47(1):1–18.

Article  PubMed  Google Scholar 

Armontrout J, Torous J, Fisher M, Drogin E, Gutheil T. Mobile Mental Health: navigating New Rules and Regulations for Digital Tools. Curr psychiatry Rep. 2016;18(10):91.

Article  PubMed