Epiglottic abscess results from the coalescence of epiglottic infection or secondary infection of epiglottic mucocele [1]. Epiglottic abscess is a potentially emergent severe disease leading to airway compromise and fatality if not correctly diagnosed and treated. A systematic review shows that 51.9 % of 10,148 adult patients with epiglottitis are admitted to an intensive care unit (ICU) for airway monitoring or sepsis management [2]. Additionally, 10.9 % of the patients still have to secure airways, and 1.5 % die of the disease [2]. Epiglottic abscess also doubles hospital stay [3]. The epiglottic abscess is typically found on the vallecular surface of the epiglottis and may be extended to the adjacent anatomical sites and neck with a higher rate of airway obstruction [3]. Interventions, such as spinal needle aspiration, have been introduced to treat epiglottic abscess [4]. The efficacy of these interventions is still questionable, which demands more techniques and procedures to early and securely prevent serious complications. It would be better to have early surgical intervention to resolve patient symptoms and secure airway by transoral laser-assisted marsupialization of epiglotic abscess. This was a safe, simple, and reliable technique that guaranteed early recovery in 12 cases. Therefore, this article presents the procedures and pros and cons of this method for treating epiglottic abscess.