Introduction/Objective: To assess the performance of antenatal ultrasound markers in detecting neonatal coarctation of the aorta (CoA). Methods: We performed a retrospective study including fetuses with suspected CoA and no other cardiac abnormalities. Data obtained from antenatal ultrasounds included subjective assessment of ventricular and arterial asymmetry, appearance of aortic arch, presence of a persistent left superior vena cava (PLSVC), and objective Z-score measurements of the mitral (MV), tricuspid (TV), aortic (AV) and pulmonary (PV) valves. Performance of antenatal ultrasound markers in predicting postnatal CoA was then assessed. Results: Of the 83 fetuses referred for suspected CoA, 30 (36.1%) had confirmed CoA postnatally. The sensitivity and specificity for antenatal diagnosis were 83.3% (95%CI 65.3-94.4%) and 45.3% (95%CI 31.6-59.6%) respectively. Neonates with confirmed CoA had lower mean AV Z-scores (-2.1 vs -1.1, p=0.01), higher PV Z-scores (1.6 vs 0.8, p=0.03) and a lower AV/PV ratio (0.5 vs 0.6, p

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