Higuchi K.a· Goto O.a· Takahashi A.b· Akimoto T.a,c· Habu T.a· Ishikawa Y.a· Kirita K.a· Koizumi E.a· Noda H.a· Onda T.a· Omori J.a· Akimoto N.a· Kaise M.a· Yahagi N.c· Oyama T.b· Iwakiri K.a

Author affiliations

aDepartment of Gastroenterology, Nippon Medical School, Graduate School of Medicine, Tokyo, Japan
bDepartment of Endoscopy, Saku Central Hospital Advanced Care Center, Saku, Japan
cDivision of Research and Department for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan

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Article / Publication Details

First-Page Preview

Received: June 01, 2022
Accepted: September 20, 2022
Published online: December 07, 2022

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 2

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: https://www.karger.com/DIG

Abstract

Introduction: Endoscopic suturing of a mucosal defect is expected to prevent postoperative bleeding after endoscopic submucosal dissection (ESD). Endoscopic suturing causes mucosal deformity, which may interfere with endoscopic surveillance thereafter. We retrospectively investigated long-term chronological changes in mucosal suturing by endoscopic suturing. Methods: Forty-three patients who underwent endoscopic hand suturing (EHS) after gastric ESD at three institutions were enrolled. First, our hypothesis that the suturing sites healed via inflammation, disappearance of mucosal inversion, and flattening was validated. Subsequently, the duration required to reach each healing step was evaluated. Results: A total of 137 follow-up endoscopies were assessed, in which all cases showed the hypothesized chronological course on the suturing sites. The 95th percentiles of the duration when showing the disappearance of the inflammatory change and the inverted change were 63 days and 15.5 months after the procedure, respectively. Discussion/Conclusion: The data show that the mucosal deformity induced by EHS disappeared within 16 months. Endoscopic suturing is thus considered to have a negligible effect on endoscopic surveillance following the procedure.

© 2022 S. Karger AG, Basel

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First-Page Preview

Received: June 01, 2022
Accepted: September 20, 2022
Published online: December 07, 2022

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 2

ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)

For additional information: https://www.karger.com/DIG

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