Bao J. · Nunez C. · Elliott E. · Dinsmore N. · McRae J. · Morris A. · Blyth C.C. · Crawford N. · Kynaston A. · Marshall H. · Thorley B. · McIntyre P. · Britton P.N. · PAEDS investigators

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Article / Publication Details Abstract

Introduction: Acute flaccid paralysis (AFP) surveillance continues globally as part of the World Health Organization’s goal to eradicate poliomyelitis. The Australian Paediatric Surveillance Unit (APSU), Paediatric Active Enhanced Disease Surveillance (PAEDS) network, and National Enterovirus Reference Laboratory (NERL) collaborate in acute flaccid paralysis surveillance in Australia, capturing and reviewing cases of AFP for all etiologies in order to exclude poliovirus. . We aimed to describe the AFP epidemiology in childhood over an eleven year period. Methods: Data were reported nationally by paediatricians via prospective APSU surveillance, PAEDS surveillance nurses at five tertiary paediatric hospitals and NERL from 2007 to 2017. Children aged 0-15 years with AFP were included. We combined APSU, PAEDS and NERL datasets, analysed epidemiological trends and described clinical features and investigations for major diagnoses. Results: Of 590 AFP-compatible cases, 49% were male; 47% were aged 0-4 years, 9% aged

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