SEVERITY AND MORPHOLOGICAL CLASSIFICATION OF ANAEMIA AMONG CHILDREN AGED 2- 59 MONTHS IN DAR ES SALAAM, TANZANIA: A CROSS SECTIONAL STUDY PROTOCOL.

Abstract

Abstract Background: Anaemia is a significant secondary clinical diagnosis in children under the age of five in most parts of developing world, including Tanzania. studies that assess clinical conditions associated with prenatal and postnatal era are highly relevant to global health as they tend to reflect patterns of significant health challenges across the entire human lifespan. Objective: To assess for morphological characteristics and severity of anaemia among under-five population seen at Dar es Salaam regional referral facilities in Tanzania. Design & Methods: A cross-sectional hospital based study will be conducted at Temeke Regional Referral and Mbagala Rangi Tatu district hospitals in Dar es Salaam, Tanzania. All children aged 2-59 months will be eligible to participate in the study. All children aged 2 – 59 months with anaemia will be the target population. The study will depend on a self-administered questionnaire with five distinct parts. Data analysis will commence with summarisation. Specifically, continuous data will be summarised using median (with inter-quartile range) and categorical data will be summarised using frequency (and proportion by %) Graphical tools will also be employed where by important correlations as well as +/- outliers will be assessed. Besides, univariate and bivariate statistics will be computed for all clinically relevant data. Main outcome measure will be severity and morphological classification of anaemia. Unless otherwise stated, an alpha-level of 5% will be used as a limit of type 1 error in findings. Written informed consent will be sought from the parent/guardian of each participant child prior to inclusion into the study.

Competing Interest Statement

The authors have declared no competing interest.

Funding Statement

The work was solely funded by the first author .No additional funding was received for this work

Author Declarations

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Yes

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

Name: Hubert Kairuki Memorial University Approval number: HKMU/IREC/27.10/150

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

Yes

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

Yes

I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.

Yes

Data Availability

No data is available for now. It is a protocol

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