Intrinsic differences in rod and cone membrane composition: implications for cone degeneration

Baylor DA (1987) Photoreceptor signals and vision. Proctor lecture. Invest Ophthalmol Vis Sci 2:34–49

Google Scholar 

Allikmets R (1997) A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy. Nat Genet 17:122

CAS  PubMed  Google Scholar 

Fujinami K, Lois N, Davidson AE et al (2013) A longitudinal study of Stargardt Disease: clinical and electrophysiologic assessment, progression, and genotype correlations. Am J Ophthalmol 155:1075–88

PubMed  Article  Google Scholar 

Rotenstreich Y, Fishman GA, Anderson RJ (2003) Visual acuity loss and clinical observations in a large series of patients with Stargardt disease. Ophthalmology 110:1151–8

PubMed  Article  Google Scholar 

Gomes NL, Greenstein VC, Carlson JN, Tsang SH, Smith RT, Carr RE, Hood DC, Chang S (2009) A comparison of fundus autofluorescence and retinal structure in patients with Stargardt disease. Invest Ophthalmol Vis Sci 50:3907–14

PubMed  Article  Google Scholar 

Molday LL, Rabin AR, Molday RS (2000) ABCR expression in foveal cone photoreceptors and its role in Stargardt macular dystrophy. Nat Genet 25:257–8

CAS  PubMed  Article  Google Scholar 

Cideciyan AV, Hood DC, Huang Y, Banin E, Li ZY, Stone EM, Milam AH, Jacobson SG (1998) Disease sequence from mutant rhodopsin allele to rod and cone photoreceptor degeneration in man. Proc Natl Acad Sci USA 95:7103–8

CAS  PubMed  PubMed Central  Article  Google Scholar 

Dubis AM, Hansen BR, Cooper RF, Beringer J, Dubra A, Carroll J (2012) Relationship between the foveal avascular zone and foveal pit morphology. Invest Ophthalmol Vis Sci 53:1628–36

PubMed  PubMed Central  Article  Google Scholar 

Chong NH, Keonin J, Luthert PJ, Frennesson CI, Weingeist DM, Wolf RL, Mullins RF, Hageman GS (2005) Decreased thickness and integrity of the macular elastic layer of Bruch’s membrane correspond to the distribution of lesions associated with age-related macular degeneration. Am J Pathol 166:241–51

PubMed  PubMed Central  Article  Google Scholar 

Mainster MA (1987) Light and macular degeneration: a biophysical and clinical perspective. Eye 1:304–10

PubMed  Article  Google Scholar 

Curcio CA, Sloan KR Jr, Packer O, Hendrickson AE, Kalina RE (1987) Distribution of cones in human and monkey retina: individual variability and radial asymmetry. Science 236:579–82

CAS  PubMed  Article  Google Scholar 

Cideciyan AV, Swider M, Aleman TS, Sumaroka A, Schwartz SB, Roman MI, Milam AH, Bennett J, Stone EM, Jacobson SG (2005) ABCA4-associated retinal degenerations spare structure and function of the human parapapillary retina. Invest Ophthalmol Vis Sci 46:4739–46

PubMed  Article  Google Scholar 

Burke TR, Fishman GA, Zernant J et al (2012) Retinal phenotypes in patients homozygous for the G1961E mutation in the ABCA4 gene. Invest Ophthalmol Vis Sci 53:4458–67

CAS  PubMed  PubMed Central  Article  Google Scholar 

Burke TR, Duncker T, Woods RL et al (2014) Quantitative fundus autofluorescence in recessive Stargardt disease. Invest Ophthalmol Vis Sci 55:2841–52

CAS  PubMed  PubMed Central  Article  Google Scholar 

Weng J, Mata NL, Azarian SM, Tzekov RT, Birch DG, Travis GH (1999) Insights into the function of Rim protein in photoreceptors and etiology of Stargardt’s disease from the phenotype in abcr knockout mice. Cell 98:13–23

CAS  PubMed  Article  Google Scholar 

Kim SR, Fishkin N, Kong J, Nakanishi K, Allikmets R, Sparrow JR (2004) Rpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E. Proc Natl Acad Sci U S A 101:11668–72

CAS  PubMed  PubMed Central  Article  Google Scholar 

Sparrow JR, Gregory-Roberts E, Yamamoto K, Blonska A, Ghosh SK, Ueda K, Zhou J (2012) The Bisretinoids of Retinal Pigment Epithelium. Prog Retin Eye Res 31:121–35

CAS  PubMed  Article  Google Scholar 

Beharry S, Zhong M, Molday RS (2004) N-retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR). J Biol Chem 279:53972–9

CAS  PubMed  Article  Google Scholar 

Kim HJ, Sparrow JR (2021) Bisretinoid phospholipid and vitamin A aldehyde: shining a light. J Lipid Res 62:100042

CAS  PubMed  PubMed Central  Article  Google Scholar 

Sparrow JR, Marsiglia M, Allikmets R, Tsang S, Lee W, Duncker T, Zernant J (2015) Flecks in recessive Stargardt disease: short-wavelength autofluorescence, near-infrared autofluorescence, and optical coherence tomography. Invest Ophthalmol Vis Sci 56:5029–39

PubMed  PubMed Central  Article  Google Scholar 

Fakin A, Robson AG, Fujinami K, Moore AT, Michaelides M, Pei-Wen Chiang J, Holder GE, Webster AR (2016) Phenotype and progression of retinal degeneration associated with nullizigosity of ABCA4. Invest Ophthalmol Vis Sci. 57:4668–78

CAS  PubMed  Article  Google Scholar 

Conley SM, Cai X, Makkia R, Wu Y, Sparrow JR, Naash MI (2012) Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt’s dystrophy. Biochim Biophys Acta 1822:1169–79

CAS  PubMed  Article  Google Scholar 

Mears AJ, Kondo M, Swain PK, Takada Y, Bush RA, Saunders TL, Sieving PA, Swaroop A (2001) Nrl is required for rod photoreceptor development. Nat Genet 29:447–52

CAS  PubMed  Article  Google Scholar 

Jeon CJ, Strettoi E, Masland RH (1998) The major cell populations of the mouse retina. J Neurosci 18:8936–8946

CAS  PubMed  PubMed Central  Article  Google Scholar 

Sandu C, Hicks D, Felder-Schmittbuhl MP (2011) Rat photoreceptor circadian oscillator strongly relies on lighting conditions. Eur J Neurosci 34:507–16

PubMed  Article  Google Scholar 

Molday RS, Hicks D, Molday L (1987) Peripherin. A rim-specific membrane protein of rod outer segment discs. Invest Ophthalmol Vis Sc 28:50–61

CAS  Google Scholar 

Bascom RA, Manara S, Collins L, Molday RS, Kalnins VI, McInnes RR (1992) Cloning of the cDNA for a novel photoreceptor membrane protein (rom-1) identifies a disk rim protein family implicated in human retinopathies. Neuron 8:1171–84

CAS  PubMed  Article  Google Scholar 

Papermaster DS (1982) Preparation of retinal rod outer segments. Methods Enzymol 81:48–52

CAS  PubMed  Article  Google Scholar 

Poincelot RP, Abrahamson EW (1970) Fatty acid composition of bovine rod outer segments and rhodopsin. Biochim Biophys Acta 202:382–5

CAS  PubMed  Article  Google Scholar 

Kwok MC, Holopainen JM, Molday LL, Foster LJ, Molday RS (2008) Proteomics of photoreceptor outer segments identifies a subset of SNARE and Rab proteins implicated in membrane vesicle trafficking and fusion. Mol Cell Proteomics 7:1053–66

CAS  PubMed  PubMed Central  Article  Google Scholar 

Jonas JB, Schneider U, Naumann GO (1992) Count and density of human retinal photoreceptors. Graefes Arch Clin Exp Ophthalmol 230:505–10

CAS  PubMed  Article  Google Scholar 

Johnson LV, Hageman GS, Blanks JC (1985) Restricted extracellular matrix domains ensheath cone photoreceptors in vertebrate retinae. Prog Clin Biol Res 190:33–44

CAS  PubMed  Google Scholar 

Hendrickson A, Hicks D (2002) Distribution and density of medium- and short-wavelength selective cones in the domestic pig retina. Exp Eye Res 74:435–44

CAS  PubMed  Article  Google Scholar 

Hicks D, Molday RS (1986) Differential immunogold-dextran labeling of bovine and frog rod and cone cells using monoclonal antibodies against bovine rhodopsin. Exp Eye Res 42:55–71

CAS  PubMed  Article  Google Scholar 

Roberts MR, Hendrickson A, McGuire CR, Reh TA (2005) Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina. Invest Ophthalmol Vis Sci 46:2897–904

PubMed  Article  Google Scholar 

Acar N, Berdeaux O, Grégoire S et al (2012) Lipid composition of the human eye: are red blood cells a good mirror of retinal and optic nerve fatty acids? PLoS One 7:e35102

CAS  PubMed  PubMed Central  Article  Google Scholar 

Berdeaux O, Juaneda P, Martine L, Cabaret S, Bretillon L, Acar N (2010) Identification and quantification of phosphatidylcholines containing very-long-chain polyunsaturated fatty acid in bovine and human retina using liquid chromatography/tandem mass spectrometry. J Chromatogr A 1217:7738–48

CAS  PubMed  Article  Google Scholar 

Folch J, Lees M, Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226:497–509

CAS  PubMed  Article  Google Scholar 

Morrison WR, Smith LM (1964) Preparation of fatty acid methyl esters and dimethylace

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