Chitin powder enhances growth factor production and therapeutic effects of mesenchymal stem cells in a chronic kidney disease rat model

Caplan AI, Correa D. The MSC: an injury drugstore. Cell Stem Cell. 2011;9:11–5. https://doi.org/10.1016/j.stem.2011.06.008.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Sávio-Silva C, Soinski-Sousa PE, Balby-Rocha MTA, Lira ÁO, Rangel ÉB. Mesenchymal stem cell therapy in acute kidney injury (AKI): review and perspectives. Rev Assoc Med Bras. 2020;66:s45-54. https://doi.org/10.1590/1806-9282.66.S1.45.

Article  Google Scholar 

Kuppe C, Kramann R. Role of mesenchymal stem cells in kidney injury and fibrosis. Curr Opin Nephrol Hypertens. 2016;25:372–7. https://doi.org/10.1097/MNH.0000000000000230.

CAS  Article  PubMed  Google Scholar 

Griffin MD, Ryan AE, Alagesan S, Lohan P, Treacy O, Ritter T. Anti-donor immune responses elicited by allogeneic mesenchymal stem cells: what have we learned so far? Immunol Cell Biol. 2013;91:40–51. https://doi.org/10.1038/icb.2012.67.

CAS  Article  PubMed  Google Scholar 

Hori H, Iwamoto U, Niimi G, Shinzato M, Hiki Y, Tokushima Y, Kawaguchi K, Ohashi A, Nakai S, Yasutake M, Kitaguchi N. Appropriate nonwoven filters effectively capture human peripheral blood cells and mesenchymal stem cells, which show enhanced production of growth factors. J Artif Organs. 2015;18:55–63. https://doi.org/10.1007/s10047-014-0794-9.

CAS  Article  PubMed  Google Scholar 

Hori H, Shinzato M, Hiki Y, Nakai S, Niimi G, Nagao S, Kitaguchi N. Combination of nonwoven filters and mesenchymal stem cells reduced glomerulosclerotic lesions in rat chronic kidney disease models. Int J Clin Med. 2019;10:135–49. https://doi.org/10.4236/ijcm.2019.103014.

CAS  Article  Google Scholar 

Kang DH, Hughes J, Mazzali M, Schreiner GF, Johnson RJ. Impaired angiogenesis in the remnant kidney model: II. Vascular endothelial growth factor administration reduces renal fibrosis and stabilizes renal function. J Am Soc Nephrol. 2001;12:1448–57. https://doi.org/10.1681/ASN.V1271448.

CAS  Article  PubMed  Google Scholar 

Iliescu R, Fernandez SR, Kelsen S, Maric C, Chade AR. Role of renal microcirculation in experimental renovascular disease. Nephrol Dial Transplant. 2010;25:1079–87. https://doi.org/10.1093/ndt/gfp605.

CAS  Article  PubMed  Google Scholar 

Leonard EC, Friedrich JL, Basile DP. VEGF-121 preserves renal microvessel structure and ameliorates secondary renal disease following acute kidney injury. Am J Physiol Renal Physiol. 2008;295:F1648–57. https://doi.org/10.1152/ajprenal.00099.2008.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Gong R, Rifai A, Dworkin LD. Anti-inflammatory effect of hepatocyte growth factor in chronic kidney disease: targeting the inflamed vascular endothelium. J Am Soc Nephrol. 2006;17:2464–73. https://doi.org/10.1681/ASN.2006020185.

CAS  Article  PubMed  Google Scholar 

Oka M, Sekiya S, Sakiyama R, Shimizu T, Nitta K. Hepatocyte growth factor-secreting mesothelial cell sheets suppress progressive fibrosis in a rat model of CKD. J Am Soc Nephrol. 2019;30:261–76. https://doi.org/10.1681/ASN.2018050556.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Imafuku A, Oka M, Miyabe Y, Sekiya S, Nitta K, Shimizu T. Rat mesenchymal stromal cell sheets suppress renal fibrosis via microvascular protection. Stem Cells Transl Med. 2019;8:1330–41. https://doi.org/10.1002/sctm.19-0113.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Singh R, Shitiz K, Singh A. Chitin and chitosan: biopolymers for wound management. Int Wound J. 2017;14:1276–89. https://doi.org/10.1111/iwj.12797.

Article  PubMed  PubMed Central  Google Scholar 

Malafaya PB, Silva GA, Reis RL. Natural-origin polymers as carriers and scaffolds for biomolecules and cell delivery in tissue engineering applications. Adv Drug Deliv Rev. 2007;59:207–33. https://doi.org/10.1016/j.addr.2007.03.012.

CAS  Article  PubMed  Google Scholar 

Peter MG. Applications and environmental aspects of chitin and chitosan. J Macromol Sci A. 1995;32:629–40. https://doi.org/10.1080/10601329508010276.

Article  Google Scholar 

Tharanathan RN, Kittur FS. Chitin–the undisputed biomolecule of great potential. Crit Rev Food Sci Nutr. 2003;43:61–87. https://doi.org/10.1080/10408690390826455.

CAS  Article  PubMed  Google Scholar 

Sum Chow K, Khor E, Andrew ChweeAun Wan. Porous chitin matrices for tissue engineering: fabrication and in vitro cytotoxic assessment. J Polym Res. 2001;8:27–35. https://doi.org/10.1007/s10965-006-0132-x.

Article  Google Scholar 

Maeda Y, Jayakumar R, Nagahama H, Furuike T, Tamura H. Synthesis, characterization and bioactivity studies of novel beta-chitin scaffolds for tissue-engineering applications. Int J Biol Macromol. 2008;42:463–7. https://doi.org/10.1016/j.ijbiomac.2008.03.002.

CAS  Article  PubMed  Google Scholar 

Madhumathi K, Sudheesh Kumar PT, Kavya KC, Furuike T, Tamura H, Nair SV, Jayakumar R. Novel chitin/nanosilica composite scaffolds for bone tissue engineering applications. Int J Biol Macromol. 2009;45:289–92. https://doi.org/10.1016/j.ijbiomac.2009.06.009.

CAS  Article  PubMed  Google Scholar 

Peter M, Sudheesh Kumar PT, Binulal NS, Nair SV, Tamura H, Jayakumar R. Development of novel α-chitin/nanobioactive glass ceramic composite scaffolds for tissue engineering applications. Carbohydr Polym. 2009;78:926–31. https://doi.org/10.1016/j.carbpol.2009.07.016.

CAS  Article  Google Scholar 

Iwamoto U, Hori H, Takami Y, Tokushima Y, Shinzato M, Yasutake M, Kitaguchi N. A novel cell-containing device for regenerative medicine: biodegradable nonwoven filters with peripheral blood cells promote wound healing. J Artif Organs. 2015;18:315–21. https://doi.org/10.1007/s10047-015-0845-x.

CAS  Article  PubMed  Google Scholar 

Song IH, Jung KJ, Lee TJ, Kim JY, Sung EG, Bae YC, Park YH. Mesenchymal stem cells attenuate adriamycin-induced nephropathy by diminishing oxidative stress and inflammation via downregulation of the NF-kB. Nephrology (Carlton). 2018;23:483–92. https://doi.org/10.1111/nep.13047.

CAS  Article  Google Scholar 

Da Silva CA, Chalouni C, Williams A, Hartl D, Lee CG, Elias JA. Chitin is a size-dependent regulator of macrophage TNF and IL-10 production. J Immunol. 2009;182:3573–82. https://doi.org/10.4049/jimmunol.0802113.

CAS  Article  PubMed  Google Scholar 

Crisostomo PR, Wang Y, Markel TA, Wang M, Lahm T, Meldrum DR. Human mesenchymal stem cells stimulated by TNF-alpha, LPS, or hypoxia produce growth factors by an NF kappa B- but not JNK-dependent mechanism. Am J Physiol Cell Physiol. 2008;294:C675–82. https://doi.org/10.1152/ajpcell.00437.

CAS  Article  PubMed  Google Scholar 

Bertani T, Poggi A, Pozzoni R, Delaini F, Sacchi G, Thoua Y, Mecca G, Remuzzi G, Donati MB. Adriamycin-induced nephrotic syndrome in rats: sequence of pathologic events. Lab Invest. 1982;46:16–23.

CAS  PubMed  Google Scholar 

Roselli S, Gribouval O, Boute N, Sich M, Benessy F, Attié T, Gubler MC, Antignac C. Podocin localizes in the kidney to the slit diaphragm area. Am J Pathol. 2002;160:131–9. https://doi.org/10.1016/S0002-9440(10)64357-X.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Zhu B, Wang Y, Jardine M, Jun M, Lv JC, Cass A, Liyanage T, Chen HY, Wang YJ, Perkovic V. Tripterygium preparations for the treatment of CKD: a systematic review and meta-analysis. Am J Kidney Dis. 2013;62:515–30. https://doi.org/10.1053/j.ajkd.2013.02.374.

CAS  Article  PubMed  Google Scholar 

Taylor A, Sharkey J, Harwood R, Scarfe L, Barrow M, Rosseinsky MJ, Adams DJ, Wilm B, Murray P. Multimodal imaging techniques show differences in homing capacity between mesenchymal stromal cells and macrophages in mouse renal injury models. Mol Imaging Biol. 2020;22:904–13. https://doi.org/10.1007/s11307-019-01458-8.

CAS  Article  PubMed  Google Scholar 

Ezquer F, Giraud-Billoud M, Carpio D, Cabezas F, Conget P, Ezquer M. Proregenerative microenvironment triggered by donor mesenchymal stem cells preserves renal function and structure in mice with severe diabetes mellitus. BioMed Res Int. 2015;2015: 164703. https://doi.org/10.1155/2015/164703.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Dai C, Saleem MA, Holzman LB, Mathieson P, Liu Y. Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria. Kidney Int. 2010;77:962–73. https://doi.org/10.1038/ki.2010.40.

CAS  Article  PubMed  PubMed Central  Google Scholar 

Zoja C, Garcia PB, Rota C, Conti S, Gagliardini E, Corna D, Zanchi C, Bigini P, Benigni A, Remuzzi G, Morigi M. Mesenchymal stem cell therapy promotes renal repair by limiting glomerular podocyte and progenitor cell dysfunction in adriamycin-induced nephropathy. Am J Physiol Renal Physiol. 2012;303:F1370–81. https://doi.org/10.1152/ajprenal.00057.2012.

CAS  Article  PubMed  Google Scholar 

Sukho P, Kirpensteijn J, Hesselink JW, van Osch GJ, Verseijden F, Bastiaansen-Jenniskens YM. Effect of cell seeding density and inflammatory cytokines on adipose tissue-derived stem cells: an in vitro study. Stem Cell Rev Rep. 2017;13:267–77. https://doi.org/10.1007/s12015-017-9719-3.

CAS  Article  PubMed  Google Scholar 

Burst VR, Gillis M, Pütsch F, Herzog R, Fischer JH, Heid P, Müller-Ehmsen J, Schenk K, Fries JW, Baldamus CA, Benzing T. Poor cell survival limits the beneficial impact of mesenchymal stem cell transplantation on acute kidney injury. Nephron Exp Nephrol. 2010;114:e107–16. https://doi.org/10.1159/000262318.

Article  PubMed  Google Scholar 

He N, Zhang L, Cui J, Li Z. Bone marrow vascular niche: home for hematopoietic stem cells. Bone Marrow Res. 2014;2014: 128436. https://doi.org/10.1155/2014/128436.

Article  PubMed  PubMed Central  Google Scholar 

Mias C, Trouche E, Seguelas MH, Calcagno F, Dignat-George F, Sabatier F, Piercecchi-Marti MD, Daniel L, Bianchi P, Calise D, Bourin P, Parini A, Cussac D. Ex vivo pretreatment with melatonin improves survival, proangiogenic/mitogenic activity, and efficiency of mesenchymal stem cells injected into ischemic kidney. Stem Cells. 2008;26:1749–57. https://doi.org/10.1634/stemcells.2007-1000.

CAS  Article  PubMed 

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